Detailed information NTG1030331

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AB6M97_RS00270
• Genome accession: NZ_CP163514
• Coordinates: 52648..53562 (+)
• Length: 304 a.a.
• NCBI ID: WP_369350858.1
• Uniprot ID: -
• Organism: Streptococcus hillyeri strain S23-3001-1
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 47648..58562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB6M97_RS00245 (AB6M97_00245)	purE	47710..48198 (+)	489	WP_121835877.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
AB6M97_RS00250 (AB6M97_00250)	purK	48185..49255 (+)	1071	WP_121835878.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
AB6M97_RS00255 (AB6M97_00255)	-	49265..50470 (+)	1206	WP_121835879.1	AAA family ATPase	-
AB6M97_RS00260 (AB6M97_00260)	-	50457..51140 (+)	684	WP_121835880.1	hypothetical protein	-
AB6M97_RS00265 (AB6M97_00265)	purB	51164..52459 (+)	1296	WP_121835881.1	adenylosuccinate lyase	-
AB6M97_RS00270 (AB6M97_00270)	comR	52648..53562 (+)	915	WP_369350858.1	helix-turn-helix domain-containing protein	Regulator
AB6M97_RS00275 (AB6M97_00275)	-	53818..54048 (+)	231	WP_121835883.1	hypothetical protein	-
AB6M97_RS00280 (AB6M97_00280)	ruvB	54315..55316 (+)	1002	WP_121835884.1	Holliday junction branch migration DNA helicase RuvB	-
AB6M97_RS00285 (AB6M97_00285)	-	55788..56819 (+)	1032	WP_369350861.1	NADH:flavin oxidoreductase/NADH oxidase	-
AB6M97_RS00290 (AB6M97_00290)	-	57099..57422 (+)	324	WP_121835886.1	PadR family transcriptional regulator	-
AB6M97_RS00295 (AB6M97_00295)	-	57431..57754 (+)	324	WP_121835887.1	hypothetical protein	-
AB6M97_RS00300 (AB6M97_00300)	-	57736..58497 (+)	762	WP_121835888.1	hypothetical protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 36129.15 Da
• Isoelectric Point: 4.3941

>NTDB_id=1030331 AB6M97_RS00270 WP_369350858.1 52648..53562(+) (comR) [Streptococcus hillyeri strain S23-3001-1]
MLNGFGQKVRDLREGLHITREEFCGDETELSIRQLARIESGQSIPTLAKVEYIAQQLGVTVGSLTDGENLELPKRYKELK
YLILRTPTYLDEERLKVREEQFDEIFEEYYDKLPEAEQVLVDIVQARFEVFNSGNKEFGSSILEDYFEQVKKKKFYGIND
MALIDLYLICVLVENFDVEFYDEVTYNQFIQNLRNQGSYLNVEDLFFLNKIYLIICSVLVKKGDYAQLEDYLDELYHLIL
KSQDFQRMPLYYMYRWKYSLSYLDDKNSAEEFYAHAILFAEMTSDLYLVKKLKDEWKKNIGEEM

Nucleotide

• Length: 915 bp

>NTDB_id=1030331 AB6M97_RS00270 WP_369350858.1 52648..53562(+) (comR) [Streptococcus hillyeri strain S23-3001-1]
ATGCTAAATGGTTTTGGTCAAAAAGTAAGAGATTTACGTGAAGGTTTGCATATTACTCGAGAAGAGTTTTGTGGCGATGA
AACCGAGTTGTCTATTCGGCAATTAGCGCGTATTGAAAGTGGGCAGTCTATTCCAACGCTAGCTAAAGTAGAATACATTG
CTCAACAACTAGGAGTAACTGTAGGAAGTCTCACAGATGGAGAAAACTTAGAATTGCCCAAGAGATATAAGGAGTTAAAG
TACCTGATATTAAGAACTCCCACTTATCTAGACGAAGAGCGCTTAAAAGTTCGCGAAGAGCAATTTGATGAGATTTTTGA
GGAATATTATGATAAGTTGCCAGAAGCTGAACAAGTGTTAGTTGATATTGTACAAGCAAGATTTGAAGTTTTTAATAGTG
GCAATAAAGAGTTCGGATCAAGTATTCTAGAGGATTATTTTGAACAAGTAAAAAAGAAAAAATTTTATGGTATTAATGAT
ATGGCTTTAATTGATCTTTATCTGATTTGTGTGCTTGTTGAAAATTTTGATGTAGAATTTTATGATGAGGTCACTTATAA
TCAATTTATTCAAAATTTAAGGAATCAAGGATCATATTTAAATGTTGAGGATTTATTTTTCTTAAATAAAATTTATCTTA
TAATCTGCTCGGTATTGGTCAAAAAAGGAGACTATGCACAATTGGAGGATTATTTAGATGAGTTATATCACCTTATTTTA
AAAAGTCAGGATTTCCAACGAATGCCACTTTATTATATGTATCGTTGGAAATACAGTTTATCTTATTTAGATGATAAAAA
TAGTGCTGAAGAATTTTATGCGCACGCTATTCTTTTTGCAGAGATGACTAGTGATTTGTATTTAGTCAAAAAATTAAAAG
ATGAGTGGAAGAAGAATATCGGTGAGGAGATGTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (10-62)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	54.248	100	0.546
comR	Streptococcus pyogenes MGAS8232	49	98.684	0.484
comR	Streptococcus mutans UA159	45.485	98.355	0.447
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.238	96.711	0.437
comR	Streptococcus suis P1/7	39.59	96.382	0.382
comR	Streptococcus suis 05ZYH33	39.59	96.382	0.382