Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   AB6M99_RS08000 Genome accession   NZ_CP163513
Coordinates   1664973..1665635 (-) Length   220 a.a.
NCBI ID   WP_121835774.1    Uniprot ID   A0A3L9DNN5
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1645138..1665635 1664973..1665635 within 0


Gene organization within MGE regions


Location: 1645138..1665635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS07865 (AB6M99_07865) - 1645138..1645875 (-) 738 WP_121835751.1 helix-turn-helix domain-containing protein -
  AB6M99_RS07870 (AB6M99_07870) - 1646060..1646245 (+) 186 WP_121835752.1 helix-turn-helix transcriptional regulator -
  AB6M99_RS07875 (AB6M99_07875) - 1646335..1646568 (+) 234 WP_121835753.1 hypothetical protein -
  AB6M99_RS07880 (AB6M99_07880) - 1646737..1647045 (+) 309 WP_121835754.1 hypothetical protein -
  AB6M99_RS07885 (AB6M99_07885) - 1647026..1647232 (+) 207 WP_121835755.1 hypothetical protein -
  AB6M99_RS07890 (AB6M99_07890) - 1647219..1647698 (+) 480 WP_245962708.1 hypothetical protein -
  AB6M99_RS07895 (AB6M99_07895) - 1647691..1648098 (+) 408 WP_121835756.1 hypothetical protein -
  AB6M99_RS07900 (AB6M99_07900) - 1648227..1648490 (+) 264 WP_121835757.1 hypothetical protein -
  AB6M99_RS07905 (AB6M99_07905) - 1648920..1649150 (+) 231 WP_121835758.1 hypothetical protein -
  AB6M99_RS07910 (AB6M99_07910) - 1649135..1649329 (+) 195 WP_121835759.1 hypothetical protein -
  AB6M99_RS07915 (AB6M99_07915) - 1649343..1649681 (+) 339 WP_121835760.1 HTH domain-containing protein -
  AB6M99_RS07920 (AB6M99_07920) - 1649890..1650228 (+) 339 WP_142925595.1 hypothetical protein -
  AB6M99_RS07925 (AB6M99_07925) - 1650185..1651711 (+) 1527 WP_121835762.1 phage/plasmid primase, P4 family -
  AB6M99_RS07930 (AB6M99_07930) - 1652232..1652773 (+) 542 Protein_1547 site-specific integrase -
  AB6M99_RS07935 (AB6M99_07935) - 1653563..1654231 (+) 669 WP_121835765.1 Fic family protein -
  AB6M99_RS07940 (AB6M99_07940) - 1654853..1655005 (+) 153 WP_183121669.1 hypothetical protein -
  AB6M99_RS07945 (AB6M99_07945) - 1655024..1656526 (+) 1503 WP_369351206.1 ATP-binding cassette domain-containing protein -
  AB6M99_RS07950 (AB6M99_07950) - 1656542..1656712 (-) 171 WP_121835767.1 hypothetical protein -
  AB6M99_RS07955 (AB6M99_07955) - 1656729..1657283 (-) 555 WP_121835768.1 GNAT family N-acetyltransferase -
  AB6M99_RS07960 (AB6M99_07960) obgE 1657478..1658791 (-) 1314 WP_121835769.1 GTPase ObgE -
  AB6M99_RS07965 (AB6M99_07965) - 1659058..1659186 (-) 129 WP_083959937.1 DUF4044 domain-containing protein -
  AB6M99_RS07970 (AB6M99_07970) - 1659329..1660579 (+) 1251 WP_369350515.1 aminopeptidase -
  AB6M99_RS07975 (AB6M99_07975) asnA 1660692..1661684 (-) 993 WP_121835771.1 aspartate--ammonia ligase -
  AB6M99_RS07980 (AB6M99_07980) - 1661765..1662829 (-) 1065 WP_121835772.1 MmcQ/YjbR family DNA-binding protein -
  AB6M99_RS07990 (AB6M99_07990) rplS 1663228..1663575 (-) 348 WP_027971744.1 50S ribosomal protein L19 -
  AB6M99_RS07995 (AB6M99_07995) raiA 1664338..1664886 (-) 549 WP_121835773.1 ribosome-associated translation inhibitor RaiA -
  AB6M99_RS08000 (AB6M99_08000) comFC/cflB 1664973..1665635 (-) 663 WP_121835774.1 ComF family protein Machinery gene

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25328.41 Da        Isoelectric Point: 9.1466

>NTDB_id=1030302 AB6M99_RS08000 WP_121835774.1 1664973..1665635(-) (comFC/cflB) [Streptococcus hillyeri strain S23-3001-2]
MTCLICAAELKKRPSFQELLTLAPSKTLVCSACSSTFEKIAEQHCPLCYRYGESEVCSDCLYWQKQGKSVNHQAIYCYNT
AMKAYFSRYKFQGDYLLRKVFLNDLKLALKSYREYTLVPIPLSDKRKAERGFNQVTGLLDGTGLSYQELLIKREVKKQSD
KSRAERLQSQNPFELRFDKALPDKILLIDDIYTTGMTLQLAAQLFHEKGVKEIKTFSLAR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1030302 AB6M99_RS08000 WP_121835774.1 1664973..1665635(-) (comFC/cflB) [Streptococcus hillyeri strain S23-3001-2]
ATGACCTGTTTAATATGCGCAGCTGAGCTTAAAAAACGCCCTAGTTTTCAAGAACTATTAACCTTAGCTCCCTCTAAGAC
CCTGGTTTGCTCCGCTTGTTCCTCGACTTTTGAAAAAATAGCAGAGCAGCATTGCCCCTTGTGTTATAGATATGGGGAAA
GCGAGGTTTGTAGCGATTGTCTCTACTGGCAGAAGCAGGGAAAGTCGGTTAATCATCAGGCAATCTATTGCTACAATACT
GCCATGAAAGCCTATTTCAGTCGCTATAAATTTCAGGGTGATTATCTCTTACGAAAAGTATTTCTGAATGACTTAAAACT
TGCCTTGAAATCTTATCGCGAATATACTCTGGTTCCTATTCCATTAAGTGACAAGCGAAAGGCAGAGCGTGGTTTTAATC
AAGTAACAGGATTATTGGATGGTACTGGCTTATCTTATCAAGAATTATTGATAAAAAGAGAGGTAAAAAAGCAATCGGAT
AAATCTCGTGCAGAACGTTTGCAATCTCAAAATCCTTTTGAGTTAAGGTTCGATAAAGCTTTGCCTGATAAAATCCTTCT
CATAGATGACATTTATACAACTGGAATGACTTTACAGTTAGCAGCCCAGCTTTTTCATGAAAAAGGAGTGAAAGAAATAA
AAACATTTTCACTAGCACGCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L9DNN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae R6

50.455

100

0.505
  comFC/cflB Streptococcus pneumoniae Rx1

50.455

100

0.505
  comFC/cflB Streptococcus pneumoniae D39

50.455

100

0.505
  comFC/cflB Streptococcus mitis SK321

50.455

100

0.505
  comFC/cflB Streptococcus pneumoniae TIGR4

50.455

100

0.505
  comFC/cflB Streptococcus mitis NCTC 12261

50

100

0.5
  comFC Bacillus subtilis subsp. subtilis str. 168

36.245

100

0.377

Multiple sequence alignment