Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   AB6M99_RS05745 Genome accession   NZ_CP163513
Coordinates   1232740..1234047 (-) Length   435 a.a.
NCBI ID   WP_121834666.1    Uniprot ID   -
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1227740..1239047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS05720 (AB6M99_05720) - 1228229..1229506 (-) 1278 WP_121834670.1 pyrimidine-nucleoside phosphorylase -
  AB6M99_RS05725 (AB6M99_05725) - 1229661..1230254 (-) 594 WP_121834669.1 class I SAM-dependent methyltransferase -
  AB6M99_RS05730 (AB6M99_05730) coaA 1230502..1231422 (+) 921 WP_121834668.1 type I pantothenate kinase -
  AB6M99_RS05735 (AB6M99_05735) rpsT 1231457..1231723 (+) 267 WP_121834727.1 30S ribosomal protein S20 -
  AB6M99_RS05740 (AB6M99_05740) - 1231774..1232295 (+) 522 WP_121834667.1 AAA family ATPase -
  AB6M99_RS05745 (AB6M99_05745) ciaH 1232740..1234047 (-) 1308 WP_121834666.1 cell wall metabolism sensor histidine kinase WalK Regulator
  AB6M99_RS05750 (AB6M99_05750) ciaR 1234040..1234714 (-) 675 WP_121834665.1 response regulator transcription factor Regulator
  AB6M99_RS05755 (AB6M99_05755) - 1235021..1237552 (-) 2532 WP_121834664.1 M1 family metallopeptidase -
  AB6M99_RS05760 (AB6M99_05760) phoU 1237774..1238427 (-) 654 WP_121834663.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 49596.83 Da        Isoelectric Point: 7.4523

>NTDB_id=1030295 AB6M99_RS05745 WP_121834666.1 1232740..1234047(-) (ciaH) [Streptococcus hillyeri strain S23-3001-2]
MVKIVTLWRTDKENPKTFLRFLSVFTGIFFVMTVIILQVIRMGIYSSVDTSLTNAVASVDAYVNMAMTRNFYVNNTDTAV
IIEAFPNKEKPKEKMMNVDALFYDENGNLFNTADAFSNFSNVALNVKHLGKIIEGDTVSPYGQLESYHAITVAVDNASYP
QVKYATFLVSIKQIEESTKRSFTIIMTVMILFWFVSIGVSVYLAYWSRKPIVESYEKQKSFVENASHELRTPLAVLQNRL
ESLFRRPDSTVLENSENIASSLEEVRNMRLLTTNLLNLARRDDGLQLEITEISPTFFSDIFNNYQMIAEDAQKEFTSQNL
VNRSIKSDKTLLKQLMTILFDNAVKYTSDDGKIHFEVRTTDKHFYITAMDDGFGIKDEDKKKVFDRFYRVDKARTRQKGG
FGLGLSLAKQITDSLGGQITIKDNTPKGSIFEVKL

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=1030295 AB6M99_RS05745 WP_121834666.1 1232740..1234047(-) (ciaH) [Streptococcus hillyeri strain S23-3001-2]
ATGGTTAAAATCGTAACGTTGTGGCGAACAGATAAGGAAAATCCCAAAACCTTTTTAAGATTTCTATCTGTTTTTACCGG
CATTTTCTTTGTGATGACGGTTATTATTCTTCAAGTCATTCGGATGGGCATTTATTCGTCTGTTGATACCAGTCTGACAA
ATGCAGTGGCTTCGGTAGATGCATACGTTAATATGGCAATGACACGTAATTTTTATGTTAATAATACTGATACAGCAGTC
ATTATCGAAGCTTTTCCCAATAAGGAAAAACCCAAAGAGAAAATGATGAACGTGGATGCCCTCTTTTATGATGAGAATGG
TAATCTTTTTAATACAGCGGATGCTTTTTCCAATTTTTCTAATGTTGCCTTAAATGTCAAACATCTCGGAAAAATTATCG
AAGGAGATACAGTGAGTCCCTATGGTCAGCTTGAAAGCTATCATGCTATTACGGTAGCAGTTGATAATGCGAGTTATCCG
CAGGTTAAGTATGCAACATTTTTGGTCAGTATTAAACAAATTGAAGAGTCAACCAAACGCTCCTTCACCATCATTATGAC
GGTTATGATACTCTTTTGGTTTGTCTCTATAGGTGTGAGTGTCTATTTAGCCTATTGGTCTCGTAAGCCGATTGTAGAAA
GTTATGAGAAGCAAAAAAGTTTTGTTGAAAATGCCAGTCATGAATTGCGGACGCCTTTGGCAGTGTTACAAAATCGCTTA
GAGTCGCTGTTTAGAAGACCTGACTCGACGGTTTTGGAAAATAGTGAGAATATTGCATCCAGTTTGGAAGAAGTCAGAAA
TATGCGACTGTTAACAACGAATCTCCTTAACCTTGCACGTAGAGATGATGGTCTACAATTAGAAATAACAGAGATTTCAC
CAACTTTCTTTTCTGATATTTTTAACAATTATCAGATGATTGCTGAAGATGCCCAGAAGGAATTTACAAGTCAAAATCTT
GTTAATCGTAGTATTAAATCTGATAAAACTTTACTGAAACAATTGATGACAATTCTTTTTGATAATGCTGTGAAATATAC
CAGTGATGACGGAAAGATTCATTTTGAAGTGCGAACGACAGATAAACATTTTTATATCACAGCAATGGATGATGGTTTTG
GTATCAAAGATGAGGATAAAAAGAAAGTCTTTGATAGATTTTACCGTGTTGACAAGGCAAGAACACGTCAAAAAGGTGGT
TTTGGTTTAGGCTTGTCCTTGGCAAAACAAATTACAGATTCTCTTGGAGGACAAATCACAATAAAAGATAATACGCCAAA
AGGAAGCATTTTTGAAGTGAAGTTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(219-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.865

97.241

0.572
  ciaH Streptococcus pneumoniae Rx1

49.292

97.471

0.48
  ciaH Streptococcus pneumoniae D39

49.292

97.471

0.48
  ciaH Streptococcus pneumoniae R6

49.292

97.471

0.48
  ciaH Streptococcus pneumoniae TIGR4

49.292

97.471

0.48

Multiple sequence alignment