Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AB4X21_RS02535 Genome accession   NZ_CP163380
Coordinates   472888..473625 (+) Length   245 a.a.
NCBI ID   WP_151379282.1    Uniprot ID   -
Organism   Streptococcus sp. CP1998     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 467888..478625
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS02520 (AB4X21_02520) - 468220..469782 (-) 1563 WP_155127049.1 ABC transporter substrate-binding protein/permease -
  AB4X21_RS02525 (AB4X21_02525) - 469900..471807 (+) 1908 WP_369088135.1 DUF2207 domain-containing protein -
  AB4X21_RS02530 (AB4X21_02530) - 471916..472752 (+) 837 WP_003013906.1 undecaprenyl-diphosphate phosphatase -
  AB4X21_RS02535 (AB4X21_02535) mecA 472888..473625 (+) 738 WP_151379282.1 adaptor protein MecA Regulator
  AB4X21_RS02540 (AB4X21_02540) - 473622..474779 (+) 1158 WP_369088136.1 glycosyltransferase family 4 protein -
  AB4X21_RS02545 (AB4X21_02545) sufC 474914..475684 (+) 771 WP_003004238.1 Fe-S cluster assembly ATPase SufC -
  AB4X21_RS02550 (AB4X21_02550) sufD 475751..477013 (+) 1263 WP_369088137.1 Fe-S cluster assembly protein SufD -
  AB4X21_RS02555 (AB4X21_02555) - 477023..478249 (+) 1227 WP_369088138.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28280.92 Da        Isoelectric Point: 4.0867

>NTDB_id=1029409 AB4X21_RS02535 WP_151379282.1 472888..473625(+) (mecA) [Streptococcus sp. CP1998]
MKMKQISDSTIKITIQLEDLEERGMEIADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQQLDFEDLSDLPDMEELSRMTPDEFIKTLEKTISDKTKGDAEAIHHLEQEELRDNQEQDPTPESLVSQYIYYILRFSNI
QQAVAFSKTVSFPVDTSELYKMGSDYYLTVLIDTEDQPNQYPTWLLAIIREYADDSEVTRAVLQEHGHLLMVSGAIENLK
KVASL

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1029409 AB4X21_RS02535 WP_151379282.1 472888..473625(+) (mecA) [Streptococcus sp. CP1998]
ATGAAGATGAAGCAAATTAGTGATTCAACTATTAAAATCACAATCCAACTAGAAGACTTAGAAGAACGTGGGATGGAAAT
TGCTGATTTTCTTGTCCCGCAAGAAAAAACAGAAGAATTTTTCTACGCCATTTTGGATGAGCTCGAAATGCCAGAAAGCT
TCCTGGATAGCGGGATGCTGAGTTTTCGTGTTACACCAAAACCAGATAAATTGGATGTTTTTGTTACCAAATCAAAAATT
GACCAACAATTGGATTTTGAGGATTTGTCAGATCTTCCTGATATGGAAGAGTTGTCGCGCATGACGCCAGATGAATTTAT
CAAAACCTTGGAAAAAACAATCTCTGATAAGACAAAAGGGGATGCAGAAGCTATTCACCATTTGGAACAAGAAGAGTTAC
GTGACAATCAAGAACAAGATCCGACACCTGAATCACTAGTAAGTCAGTATATTTATTACATTTTGCGTTTTTCAAATATC
CAGCAAGCAGTTGCCTTTTCAAAAACGGTCAGCTTTCCAGTGGATACCTCTGAATTATACAAAATGGGATCCGATTATTA
TTTAACTGTCTTGATCGATACAGAGGATCAACCAAATCAATATCCAACCTGGTTACTTGCTATCATTCGGGAGTATGCGG
ATGATTCAGAAGTGACACGGGCAGTTCTGCAGGAACATGGTCATTTATTAATGGTGTCTGGTGCGATTGAGAATTTGAAG
AAAGTTGCTAGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.163

100

0.682
  mecA Streptococcus pneumoniae D39

68.163

100

0.682
  mecA Streptococcus pneumoniae R6

68.163

100

0.682
  mecA Streptococcus pneumoniae TIGR4

68.163

100

0.682
  mecA Streptococcus mutans UA159

49.798

100

0.502
  mecA Streptococcus thermophilus LMD-9

47.755

100

0.478
  mecA Streptococcus thermophilus LMG 18311

47.347

100

0.473

Multiple sequence alignment