Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   ABW635_RS07760 Genome accession   NZ_CP162310
Coordinates   1575503..1577416 (-) Length   637 a.a.
NCBI ID   WP_368401061.1    Uniprot ID   -
Organism   Streptococcus iniae strain ZQ2205     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1570503..1582416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABW635_RS07730 (ABW635_07730) tnpA 1570664..1571128 (+) 465 Protein_1462 IS200/IS605 family transposase -
  ABW635_RS07735 (ABW635_07735) - 1571264..1571620 (-) 357 WP_003101745.1 S1 RNA-binding domain-containing protein -
  ABW635_RS07740 (ABW635_07740) - 1571620..1573020 (-) 1401 WP_003101746.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ABW635_RS07745 (ABW635_07745) - 1573053..1573697 (-) 645 WP_003101747.1 response regulator transcription factor -
  ABW635_RS07750 (ABW635_07750) - 1573690..1574694 (-) 1005 WP_003101748.1 sensor histidine kinase -
  ABW635_RS07755 (ABW635_07755) liaF 1574691..1575386 (-) 696 WP_003101751.1 cell wall-active antibiotics response protein LiaF -
  ABW635_RS07760 (ABW635_07760) pknB 1575503..1577416 (-) 1914 WP_368401061.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ABW635_RS07765 (ABW635_07765) - 1577413..1578153 (-) 741 WP_003101757.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ABW635_RS07770 (ABW635_07770) rsmB 1578191..1579513 (-) 1323 WP_003101760.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ABW635_RS07775 (ABW635_07775) fmt 1579503..1580438 (-) 936 WP_003101762.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69460.21 Da        Isoelectric Point: 8.9521

>NTDB_id=1024877 ABW635_RS07760 WP_368401061.1 1575503..1577416(-) (pknB) [Streptococcus iniae strain ZQ2205]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYIQGADLKKFIQDNAPLSNTQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKTLPSIIDENPQVP
QALENVVIKATAKKLSDRYNSTFEMSRDLMTALSYNRSRERKLVFLDVESTKPLPKVTPTPAPKPTVAPVSPSNTTKQKQ
EAIADVPVKKKKSGRFFGTLLKIIFALFVIGVAFFAFLAFLVLTKPSTVKVPNVNGSSLAVAESELKSLGFKIGKVKEIE
SATVAEGNVVKTDPEAGTSKREGSKVDIYVSIGNQSFVMEDYKNQLYEDAVENLVNTYNVPRSKIKIERVVTSDYRKDMV
IAQSPSPGEKFNPKGKSKIVLSVASNDTVLMPTIVNYTYQDALAALKALGIDSKRVKAYYPDVNSATGFSKMPNPKSTMI
ISAQDPYAGVEISLSATSEISIYLYAEEPTANSSDTTTSSNSRSTASSSESHATSSSSSNPNAGTETNTDANVSPQN

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=1024877 ABW635_RS07760 WP_368401061.1 1575503..1577416(-) (pknB) [Streptococcus iniae strain ZQ2205]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGCCGCGGTGGTATGGCGGATGTTTA
CTTAGCCAATGACTTAATCTTAGATAATGAAGAAGTTGCAATTAAAGTTTTGCGAACCAATTATCAAACAGATCAAGTTG
CAGTAGCGCGTTTCCAAAGAGAAGCGCGAGCGATGGCAGAATTAAATCATCCCAACATTGTCGCTATTCGAGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATATCCAGGGCGCTGACCTTAAGAAATTTATTCAAGATAACGCTCC
TTTGTCTAACACCCAAGTTGTTAGAATCATGGAAGAAGTTTTATCTGCTATGACATTAGCCCACCAAAAAGGGATTGTTC
ATAGAGACTTGAAACCTCAAAATATTCTATTAACAAAGTCAGGTGTTGTCAAAGTTACAGACTTTGGTATTGCTGTAGCT
TTTGCTGAAACTAGTTTAACGCAGACAAATTCTATGTTAGGAAGTGTGCATTATTTATCACCAGAACAAGCCCGTGGTTC
AAAAGCCACCATTCAAAGTGATATTTATGCCATGGGAATTATGCTCTTTGAAATGTTAACAGGTCATATCCCATATGATG
GTGATAGTGCTGTTACAATTGCATTGCAGCATTTCCAAAAAACCCTTCCTTCAATTATTGACGAGAACCCGCAAGTTCCA
CAGGCTTTAGAAAATGTTGTTATTAAGGCAACTGCTAAAAAGTTAAGTGATCGTTACAATTCGACATTTGAAATGAGTCG
CGACCTAATGACTGCACTAAGTTATAATCGAAGCCGTGAACGCAAGTTAGTCTTTTTGGATGTTGAAAGCACAAAACCCT
TACCAAAAGTAACCCCGACCCCAGCACCAAAACCAACGGTAGCTCCGGTAAGTCCAAGTAATACCACTAAACAAAAACAA
GAAGCCATTGCTGATGTGCCTGTTAAGAAAAAAAAGAGTGGGCGTTTCTTTGGAACTTTATTAAAGATTATTTTTGCACT
ATTTGTTATCGGTGTTGCGTTTTTTGCCTTTCTTGCCTTTCTTGTCTTGACCAAGCCATCTACCGTAAAAGTTCCAAATG
TTAATGGAAGTAGTCTAGCGGTTGCTGAATCAGAGTTAAAATCTTTAGGGTTTAAGATTGGAAAAGTAAAAGAAATTGAG
AGTGCAACCGTTGCAGAAGGTAATGTTGTTAAAACAGATCCAGAAGCTGGAACTTCAAAACGCGAAGGCTCTAAGGTTGA
TATTTATGTTTCAATAGGTAATCAGAGTTTTGTGATGGAAGATTATAAAAATCAACTTTACGAAGATGCCGTTGAAAACC
TTGTTAACACCTACAATGTTCCAAGGTCGAAAATTAAAATTGAAAGAGTGGTAACATCCGACTATCGTAAGGATATGGTT
ATTGCCCAGTCACCTAGTCCAGGTGAGAAATTTAATCCCAAAGGAAAATCGAAGATTGTCCTCAGTGTGGCTAGTAATGA
CACAGTTTTAATGCCAACTATTGTTAACTATACTTATCAGGATGCCCTTGCAGCACTAAAAGCTTTAGGAATTGACAGTA
AGCGTGTCAAAGCTTATTATCCTGATGTTAACTCTGCTACTGGCTTTAGCAAGATGCCTAATCCAAAATCAACAATGATT
ATCAGCGCACAAGATCCATATGCAGGTGTAGAGATTTCCTTATCTGCTACTAGCGAGATTAGCATTTACCTTTATGCTGA
AGAACCAACAGCCAATAGTTCTGATACAACAACATCATCAAACAGTCGAAGTACAGCATCAAGTAGTGAGAGTCATGCCA
CAAGCAGCTCATCCTCTAACCCTAACGCAGGTACCGAAACAAACACCGATGCCAATGTATCACCTCAAAACTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-248)

PASTA domain (PASTA)

(509-585)

PASTA domain (PASTA)

(438-504)

PASTA domain (PASTA)

(369-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

63.559

92.622

0.589
  stkP/pknB Streptococcus salivarius strain HSISS4

63.258

90.581

0.573
  stkP Streptococcus pneumoniae TIGR4

56.893

80.848

0.46
  stkP Streptococcus pneumoniae D39

56.505

80.848

0.457
  stkP Streptococcus pneumoniae R6

56.505

80.848

0.457
  stkP Streptococcus pneumoniae Rx1

56.311

80.848

0.455

Multiple sequence alignment