Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AB1F57_RS13065 Genome accession   NZ_CP162268
Coordinates   2591983..2593167 (+) Length   394 a.a.
NCBI ID   WP_167786135.1    Uniprot ID   -
Organism   Streptococcus sp. ZY1909104     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2578456..2591791 2591983..2593167 flank 192


Gene organization within MGE regions


Location: 2578456..2593167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB1F57_RS12980 (AB1F57_12980) - 2578456..2579499 (-) 1044 WP_367985854.1 hypothetical protein -
  AB1F57_RS12985 (AB1F57_12985) - 2579728..2582172 (-) 2445 WP_367985855.1 SEC10/PgrA surface exclusion domain-containing protein -
  AB1F57_RS12990 (AB1F57_12990) - 2582327..2582662 (+) 336 WP_367985856.1 helix-turn-helix domain-containing protein -
  AB1F57_RS12995 (AB1F57_12995) - 2582684..2583535 (-) 852 WP_367985858.1 hypothetical protein -
  AB1F57_RS13000 (AB1F57_13000) - 2583731..2584141 (+) 411 WP_367985860.1 hypothetical protein -
  AB1F57_RS13005 (AB1F57_13005) - 2584134..2584373 (+) 240 WP_367985862.1 hypothetical protein -
  AB1F57_RS13010 (AB1F57_13010) - 2584406..2585809 (+) 1404 WP_367985863.1 FtsK/SpoIIIE domain-containing protein -
  AB1F57_RS13015 (AB1F57_13015) - 2585985..2587349 (+) 1365 WP_367985865.1 Rep family protein -
  AB1F57_RS13020 (AB1F57_13020) - 2587433..2588280 (+) 848 WP_367985866.1 IS630 family transposase -
  AB1F57_RS13025 (AB1F57_13025) - 2588306..2588572 (+) 267 WP_141600169.1 hypothetical protein -
  AB1F57_RS13030 (AB1F57_13030) - 2588569..2588904 (+) 336 WP_367985868.1 DUF771 domain-containing protein -
  AB1F57_RS13035 (AB1F57_13035) - 2588967..2590088 (+) 1122 WP_171997235.1 site-specific integrase -
  AB1F57_RS13055 (AB1F57_13055) - 2590606..2591283 (-) 678 WP_105138554.1 YoaK family protein -
  AB1F57_RS13060 (AB1F57_13060) rlmH 2591312..2591791 (-) 480 WP_105138553.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AB1F57_RS13065 (AB1F57_13065) htrA 2591983..2593167 (+) 1185 WP_167786135.1 trypsin-like peptidase domain-containing protein Regulator

Sequence

Protein


Download         Length: 394 a.a.        Molecular weight: 41331.27 Da        Isoelectric Point: 4.7643

>NTDB_id=1024721 AB1F57_RS13065 WP_167786135.1 2591983..2593167(+) (htrA) [Streptococcus sp. ZY1909104]
MKKYLKFIILFAFGFLGGISGYLVASSFQNPAAPQQAGSGETTISKVQYQNENSTTKAVEKVQDAVVSVINYQQPTPNSL
SSIFGTIESSDELAVAGEGSGVIYKKDGKDAYIVTNNHVIANAEKIDILLASGEKVSGQLVGADTYSDIAVIKIDAEKAH
SVAEFANSDSIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQTEDGQTISTNAIQTDTAINPGNSGGPLINIQGQ
VIGINSSKITSSSLANNGGVSIEGMGFAIPSNDAVSIINQLETNGKVVRPALGVHMVDLTDLSTSQLEKAGLANTDLTSG
VVVVSTQSGLPADGKLKTYDVITEINSKKIESKSDLHSALYKQKINDTITVTYYRQGKEEKVDIKLTHSTDDLS

Nucleotide


Download         Length: 1185 bp        

>NTDB_id=1024721 AB1F57_RS13065 WP_167786135.1 2591983..2593167(+) (htrA) [Streptococcus sp. ZY1909104]
ATGAAAAAGTATTTGAAATTTATCATTCTATTCGCCTTTGGTTTTCTAGGAGGAATCAGTGGCTATCTAGTTGCGTCCTC
TTTCCAAAATCCCGCAGCTCCACAGCAAGCGGGGTCTGGTGAAACCACCATCAGCAAAGTTCAGTATCAAAATGAGAATT
CAACAACCAAGGCTGTGGAAAAAGTACAGGATGCCGTAGTATCTGTCATCAATTACCAGCAGCCTACACCAAATAGCCTC
AGCTCTATTTTTGGTACTATTGAGAGCTCCGATGAGCTGGCCGTGGCAGGAGAGGGATCTGGTGTTATATATAAAAAAGA
TGGCAAGGATGCCTACATTGTCACCAACAATCACGTTATTGCCAATGCTGAAAAAATTGACATTCTCTTAGCATCTGGTG
AGAAAGTTAGTGGACAGCTAGTGGGAGCAGACACCTATTCAGATATAGCCGTTATCAAGATCGATGCTGAGAAAGCCCAC
TCTGTCGCTGAATTTGCCAATTCAGACAGCATTAAGGTCGGAGAAACAGCAATCGCTATCGGTAGTCCTTTAGGTAGTGT
TTACGCCAATACCGTCACCCAGGGCATTATTTCCAGCCTTAGCCGGACTGTCACTTCTCAAACAGAGGACGGACAAACCA
TCTCCACCAATGCAATCCAAACAGATACAGCCATTAACCCAGGTAATTCTGGTGGCCCCCTCATCAATATTCAGGGTCAG
GTTATCGGAATCAATTCAAGTAAGATAACTTCAAGTTCTCTGGCCAATAATGGTGGTGTCTCTATAGAAGGTATGGGATT
TGCGATTCCTTCAAATGACGCTGTTTCTATTATCAATCAATTAGAAACAAATGGTAAGGTAGTTCGTCCAGCCTTGGGCG
TTCACATGGTCGACTTGACCGATCTGTCAACCAGTCAATTAGAAAAAGCAGGTCTGGCAAATACAGATTTAACCTCAGGT
GTAGTAGTTGTTTCAACCCAGTCAGGCCTACCAGCTGATGGCAAATTAAAAACCTACGATGTCATTACTGAGATCAATAG
TAAGAAAATTGAGAGCAAGAGCGATTTACATAGTGCCCTTTACAAACAAAAAATTAACGACACGATTACAGTCACCTATT
ACCGTCAAGGCAAAGAAGAGAAGGTTGACATAAAGTTGACACACTCTACGGACGACCTTTCTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(290-386)

Trypsin-like peptidase domain (Trypsin_2)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

60.253

100

0.604
  htrA Streptococcus gordonii str. Challis substr. CH1

59.241

100

0.594
  htrA Streptococcus pneumoniae Rx1

56.997

99.746

0.569
  htrA Streptococcus pneumoniae D39

56.997

99.746

0.569
  htrA Streptococcus pneumoniae R6

56.997

99.746

0.569
  htrA Streptococcus pneumoniae TIGR4

56.997

99.746

0.569
  htrA Streptococcus mitis NCTC 12261

56.997

99.746

0.569

Multiple sequence alignment