Detailed information NTG1024691

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: AB1F57_RS04615
• Genome accession: NZ_CP162268
• Coordinates: 907965..908639 (+)
• Length: 224 a.a.
• NCBI ID: WP_105138222.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZY1909104
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 902965..913639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB1F57_RS04580 (AB1F57_04580)	-	904164..904673 (+)	510	WP_167785661.1	EbsA family protein	-
AB1F57_RS04585 (AB1F57_04585)	-	904641..904835 (-)	195	WP_105110914.1	ferredoxin	-
AB1F57_RS04590 (AB1F57_04590)	-	904884..905414 (+)	531	WP_105138224.1	SAG1386/EF1546 family surface-associated protein	-
AB1F57_RS04595 (AB1F57_04595)	cmk	905423..906100 (+)	678	WP_125265821.1	(d)CMP kinase	-
AB1F57_RS04600 (AB1F57_04600)	infC	906281..906802 (+)	522	WP_161943039.1	translation initiation factor IF-3	-
AB1F57_RS04605 (AB1F57_04605)	rpmI	906830..907030 (+)	201	WP_024375714.1	50S ribosomal protein L35	-
AB1F57_RS04610 (AB1F57_04610)	rplT	907083..907442 (+)	360	WP_105110910.1	50S ribosomal protein L20	-
AB1F57_RS04615 (AB1F57_04615)	ciaR	907965..908639 (+)	675	WP_105138222.1	response regulator transcription factor	Regulator
AB1F57_RS04620 (AB1F57_04620)	-	908629..909987 (+)	1359	WP_367986164.1	sensor histidine kinase	-
AB1F57_RS04625 (AB1F57_04625)	rpsT	910049..910297 (-)	249	WP_170239180.1	30S ribosomal protein S20	-
AB1F57_RS04630 (AB1F57_04630)	coaA	910356..911276 (-)	921	WP_105122582.1	type I pantothenate kinase	-
AB1F57_RS04635 (AB1F57_04635)	-	911385..911975 (+)	591	WP_105138219.1	class I SAM-dependent methyltransferase	-
AB1F57_RS04640 (AB1F57_04640)	-	911972..913249 (+)	1278	WP_367986165.1	pyrimidine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25555.23 Da
• Isoelectric Point: 4.2134

>NTDB_id=1024691 AB1F57_RS04615 WP_105138222.1 907965..908639(+) (ciaR) [Streptococcus sp. ZY1909104]
MIKILLVEDDVSLSNSVFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKDGFQVLKEIREKGISTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNDNQLEFGNVTVDLSTNMTYVDGSEIEFLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTVFADRLQTLRSVGYILKNDQ

Nucleotide

• Length: 675 bp

>NTDB_id=1024691 AB1F57_RS04615 WP_105138222.1 907965..908639(+) (ciaR) [Streptococcus sp. ZY1909104]
ATGATTAAAATATTGCTTGTTGAAGACGATGTAAGCCTATCTAATTCGGTGTTCGACTTTCTAGATGATTTTGCTGATGT
TATGCAGGTTTTTGATGGCGATGAGGGCCTCTATGAGGCAGAATCAGGTGTCTATGATCTGATTCTCTTGGACCTGATGT
TGCCAGAGAAGGATGGATTTCAGGTCTTAAAAGAAATCCGCGAAAAAGGAATTTCTACTCCGGTCCTGATTATGACGGCT
AAAGAAAGCTTGGATGATAAGGGCCACGGTTTTGAATTGGGGGCGGATGATTACCTGACCAAGCCATTTTATCTAGAGGA
GTTGAAGATGCGTATTCAGGCGCTTTTGAAGCGAGCTGGTAAATTCAATGATAATCAGCTAGAATTTGGCAATGTAACTG
TTGATTTGTCTACTAATATGACCTATGTGGACGGCAGTGAAATTGAGTTCCTAGGAAAAGAATTTGATTTACTGGTTTAT
TTCTTGCAAAACCAGAACGTTATTCTTCCTAAAACTCAAATTTTTGATCGTATTTGGGGCTTTGACAGCGATACGACCAT
CTCAGTAGTAGAGGTCTATGTTTCAAAAGTCCGAAAGAAATTAAAGGGAACGGTTTTCGCAGACCGTTTACAGACCTTAA
GAAGTGTAGGGTATATTTTGAAAAATGATCAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	86.607	100	0.866
ciaR	Streptococcus pneumoniae D39	86.607	100	0.866
ciaR	Streptococcus pneumoniae R6	86.607	100	0.866
ciaR	Streptococcus pneumoniae TIGR4	86.607	100	0.866
ciaR	Streptococcus mutans UA159	86.036	99.107	0.853
covR	Lactococcus lactis subsp. lactis strain DGCC12653	37.611	100	0.379
micA	Streptococcus pneumoniae Cp1015	34.615	100	0.362