Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQM62_RS03250 Genome accession   NZ_LS483418
Coordinates   634712..635374 (+) Length   220 a.a.
NCBI ID   WP_011922190.1    Uniprot ID   A0A0H3MVS9
Organism   Streptococcus suis strain NCTC10234     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 629712..640374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM62_RS03230 (NCTC10234_00627) - 630429..631358 (-) 930 WP_012775038.1 ABC transporter substrate-binding protein -
  DQM62_RS03235 (NCTC10234_00628) - 631371..632156 (-) 786 WP_011922762.1 ABC transporter ATP-binding protein -
  DQM62_RS03240 (NCTC10234_00629) - 632308..633753 (-) 1446 WP_011922188.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  DQM62_RS03245 (NCTC10234_00630) - 633900..634649 (+) 750 WP_012775039.1 lysophospholipid acyltransferase family protein -
  DQM62_RS03250 (NCTC10234_00631) comEA/celA/cilE 634712..635374 (+) 663 WP_011922190.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQM62_RS03255 (NCTC10234_00632) comEC/celB 635358..637595 (+) 2238 WP_012775040.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQM62_RS09960 (NCTC10234_00633) - 637612..637737 (+) 126 Protein_569 IS982 family transposase -
  DQM62_RS03260 (NCTC10234_00634) - 637920..638576 (+) 657 WP_011922763.1 CBS domain-containing protein -
  DQM62_RS03265 (NCTC10234_00635) - 638670..639497 (+) 828 WP_011922194.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23410.01 Da        Isoelectric Point: 4.0676

>NTDB_id=1024019 DQM62_RS03250 WP_011922190.1 634712..635374(+) (comEA/celA/cilE) [Streptococcus suis strain NCTC10234]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQASSSQEQTEETSTEESEELSQLTVDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSPEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVNDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1024019 DQM62_RS03250 WP_011922190.1 634712..635374(+) (comEA/celA/cilE) [Streptococcus suis strain NCTC10234]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTTTTAATATTCAGCCAACCTGCTAAGTCTGATCAAACAGGACTGACAGATTTTCCTCAAACCGAGCAAG
CTTCTAGCAGTCAGGAGCAGACGGAGGAAACCAGTACAGAAGAGAGTGAGGAGCTCAGCCAGCTAACCGTTGATGTCAAA
GGAGCGGTGGAAAAGCCTGGGTTATATACTTTAGAAGCTGGTGCGCGTGTCAATGACGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTAGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCTCCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCAAACGGTGGCTTCAAGTCGGTGAACGACCTCAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(157-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MVS9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae D39

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae R6

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis SK321

46.637

100

0.473
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

37.788

98.636

0.373
  comEA Bacillus subtilis subsp. subtilis str. 168

37.559

96.818

0.364

Multiple sequence alignment