Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   AB2M33_RS07120 Genome accession   NZ_CP161921
Coordinates   1489225..1491384 (+) Length   719 a.a.
NCBI ID   WP_188884863.1    Uniprot ID   -
Organism   Lactobacillus gasseri strain MG4644     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1484225..1496384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB2M33_RS07095 udk 1484661..1485296 (-) 636 WP_367719157.1 uridine kinase -
  AB2M33_RS07100 - 1485458..1486825 (+) 1368 Protein_1350 MFS transporter -
  AB2M33_RS07105 - 1486968..1487108 (+) 141 WP_049149917.1 hypothetical protein -
  AB2M33_RS07110 - 1487099..1488418 (+) 1320 WP_223225710.1 GHKL domain-containing protein -
  AB2M33_RS07115 - 1488415..1489212 (+) 798 WP_188884862.1 LytTR family DNA-binding domain-containing protein -
  AB2M33_RS07120 comA 1489225..1491384 (+) 2160 WP_188884863.1 peptide cleavage/export ABC transporter Regulator
  AB2M33_RS07125 - 1491395..1491987 (+) 593 Protein_1355 hypothetical protein -
  AB2M33_RS07130 - 1492037..1492321 (+) 285 WP_188884864.1 bacteriocin immunity protein -
  AB2M33_RS07135 - 1492590..1492823 (+) 234 WP_095669891.1 hypothetical protein -
  AB2M33_RS07140 - 1493064..1494455 (-) 1392 WP_367719033.1 IS3 family transposase -
  AB2M33_RS07145 - 1494656..1494937 (+) 282 WP_049150795.1 hypothetical protein -
  AB2M33_RS07150 - 1495358..1495756 (+) 399 WP_049150798.1 hypothetical protein -
  AB2M33_RS07155 - 1495884..1496198 (+) 315 WP_049150799.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 719 a.a.        Molecular weight: 81193.51 Da        Isoelectric Point: 8.5460

>NTDB_id=1023137 AB2M33_RS07120 WP_188884863.1 1489225..1491384(+) (comA) [Lactobacillus gasseri strain MG4644]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKAAQKFNFKTEAVKADMSLFDENS
IQYPFIAHVLKQGELLHYYVVLKNAKNYLVIADPDPSVSVVKMPKDRFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNILGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPVYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSENTRYRRIDSQFVDYLKKTFKYSKTENLQTALKTFIQ
LSLNVIVLWVGAKVVMQGQLSIGQLMTFNALLAYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVKSEFNQKTTIEDRKL
LEGNIEYKNVDYRYGYGTDVLKDINLKINQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVILNGHATSEINKHTLRSY
VNYVPQTPYIFSGTVKENLLLGSRPDITEEDVIKACQIAGIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDRTIIFIAHRLAIAERADKVVVIDRGQIVEEGSHSELMSKPGFYYDLVKG

Nucleotide


Download         Length: 2160 bp        

>NTDB_id=1023137 AB2M33_RS07120 WP_188884863.1 1489225..1491384(+) (comA) [Lactobacillus gasseri strain MG4644]
ATGTTATTCAAATATAAATCCGTATACGTGCCACAAGTGGATGAGATGGATTGTGGTGTTGCTTGTTTAGCAATGATCTT
AAAGCAATATCATTCTCGCGTATCTTTAGCACATTTACGTCATGAAGCTCGTACTAATCTTGAAGGCACAACTGCTTTAG
GACTAGTGAAGGCAGCACAAAAATTTAATTTCAAAACAGAAGCCGTAAAAGCAGATATGTCTTTATTTGATGAGAATAGT
ATTCAATATCCTTTTATTGCCCACGTCCTAAAACAAGGAGAACTACTTCATTATTATGTAGTTCTTAAAAATGCTAAGAA
TTATTTAGTAATTGCAGATCCCGATCCATCAGTTAGTGTGGTAAAGATGCCTAAAGATAGGTTTGCTCAAGAATGGACAG
GGATTGCACTCTTTATGGTTCCTAACGAAGACTTTGAACCAATCAAAGAAAAGAAAAATAATTTATGGTCTCTCTTTCCG
TATATGTTTAAACAAAAGCGGCTAATGATTAACATCATTCTAGCCGCTTTATTAATGACCATAATTAGTATTTGCAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTACATTCCAGATGGAACCTATCAGACTCTTTCGATCTTAGCTGTTGGACTAT
TAATTGCTTATGTCTTTAATTCAATTTTTTCTTATGGACAGAACTTTTTATTAAATATTTTAGGTCAAAGATTAAGTATT
GATCTAAATCTGCAATACATCAGGCATATTTTTGAATTACCAATGGAATTCTTTGTAACAAGAAGAACGGGTGAAATTAC
TTCGCGTTTTTCTGATGCAAGTAGAATTATTGACGCTTTGGCAAGTACAGTTATTTCGCTCTTCTTAGATCTCTCAATTG
TGATTGTGATGGGATTAGTCTTAGCAGCACAAAATATGACATTATTTGGGATTACATTATTAGCTTTACCAGTATATGCA
GTTGTAATTTTAGGGTTTACTAAAAAGTTCGAAAAACTAAATAATGAACAAATGGAGAGTAATGCGGTTCTTAGTTCTTC
TGTAATTGAAGATATTCAAGGAATTGAAACTATTAAAGCTTTAAATAGTGAGAATACAAGATATAGAAGAATCGATAGTC
AGTTTGTAGATTACTTAAAAAAAACTTTTAAATACAGCAAAACTGAGAACTTGCAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTGTTCTTTGGGTTGGTGCAAAAGTTGTAATGCAAGGGCAATTGAGCATTGGTCAGTTGATGAC
TTTTAATGCGTTGCTGGCATATTTTATTGATCCACTGCAAAATATTATTAATCTGCAACCGCGACTTCAATCAGCTAGTG
TTGCTCAAAATCGATTAAATGAGGTCTATCAAGTAAAAAGTGAATTCAATCAGAAGACTACTATTGAAGATCGTAAGCTC
CTAGAAGGAAATATTGAATATAAGAATGTGGATTATCGCTATGGTTATGGCACAGATGTCTTAAAAGATATTAATCTAAA
AATTAACCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGATCTGGAAAATCAACAATGGTTAAGTTGTTAGTAGATT
TTTTTTCGCCAAGTAAGGGTCAAGTCATTTTAAATGGCCATGCAACAAGTGAAATTAATAAGCATACGTTGCGGTCATAT
GTGAATTATGTACCTCAAACTCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTGTTGTTAGGATCTAGACCAGATAT
CACTGAAGAAGATGTAATAAAGGCTTGTCAGATTGCTGGGATTGACCAAGAAATAGCTAATCTACCACTGCAATTTGAAA
CAAAATTAGATGAAAATGCCAAAATTTTATCTGGCGGACAAAAGCAAAGGCTAACTATTGCTCGGGCATTATTATCTCCT
GCAAAGGTATTTATCTTTGATGAAGTAACAAGTGGCTTAGATACAATTACCGAGAAGAGAGTAGTTGATAATTTGATGAA
GCTAAAGGATAGGACAATTATTTTTATCGCACATCGCCTGGCAATTGCAGAACGAGCAGATAAGGTTGTTGTGATTGATC
GTGGCCAGATAGTTGAAGAAGGCAGCCACAGCGAATTGATGAGTAAGCCTGGCTTTTATTATGACTTAGTGAAGGGATAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-143)

ABC transporter transmembrane region (ABC_membrane)

(169-439)

ABC transporter (ABC_tran)

(501-651)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

57.303

99.026

0.567
  comA Streptococcus mitis SK321

57.022

99.026

0.565
  comA Streptococcus pneumoniae Rx1

56.882

99.026

0.563
  comA Streptococcus pneumoniae D39

56.882

99.026

0.563
  comA Streptococcus pneumoniae R6

56.882

99.026

0.563
  comA Streptococcus pneumoniae TIGR4

56.742

99.026

0.562
  comA Streptococcus gordonii str. Challis substr. CH1

55.337

99.026

0.548
  comA/nlmT Streptococcus mutans UA159

53.324

98.331

0.524

Multiple sequence alignment