Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AB1395_RS01360 Genome accession   NZ_CP161815
Coordinates   254386..255144 (+) Length   252 a.a.
NCBI ID   WP_316606713.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SS-15     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 249386..260144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB1395_RS01335 (AB1395_01335) - 250659..251162 (-) 504 WP_218653972.1 phosphatidylglycerophosphatase A -
  AB1395_RS01340 (AB1395_01340) - 251366..252682 (+) 1317 WP_218653973.1 FAD-containing oxidoreductase -
  AB1395_RS01345 (AB1395_01345) - 252691..253047 (+) 357 WP_367783617.1 DUF2200 domain-containing protein -
  AB1395_RS01350 (AB1395_01350) - 253252..253809 (+) 558 WP_367783619.1 DUF1697 domain-containing protein -
  AB1395_RS01355 (AB1395_01355) - 253810..254307 (+) 498 WP_367783621.1 phosphatase PAP2 family protein -
  AB1395_RS01360 (AB1395_01360) mecA 254386..255144 (+) 759 WP_316606713.1 adaptor protein MecA Regulator
  AB1395_RS01365 (AB1395_01365) - 255145..256302 (+) 1158 WP_316606712.1 MraY family glycosyltransferase -
  AB1395_RS01370 (AB1395_01370) sufC 256410..257180 (+) 771 WP_104967221.1 Fe-S cluster assembly ATPase SufC -
  AB1395_RS01375 (AB1395_01375) - 257193..257708 (+) 516 WP_316606711.1 GNAT family N-acetyltransferase -
  AB1395_RS01380 (AB1395_01380) sufD 257712..258974 (+) 1263 WP_316606710.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 28865.46 Da        Isoelectric Point: 4.1858

>NTDB_id=1022576 AB1395_RS01360 WP_316606713.1 254386..255144(+) (mecA) [Streptococcus pluranimalium strain SS-15]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKNSGMLSFRVTPKKDRLDVFVTKSEI
DKDLNFDDLAALGDVSQMSPDEFFKTLEKSMLEKGDTEAHEKLKQMEEIVESAMTEQASEADLADESTEDNAEQDNYTHY
VLQFPMLKDAVAFSKAIDFDIEASELYKFNGSYYITILVSLENKPAYYADLVHARLLEHSRGGQKTRAYLQEHGVRLLEG
YAVADLEGIKVV

Nucleotide


Download         Length: 759 bp        

>NTDB_id=1022576 AB1395_RS01360 WP_316606713.1 254386..255144(+) (mecA) [Streptococcus pluranimalium strain SS-15]
ATGGAAATGAAACAAATTAGCGAAACAACGCTAAAAATCACGATTAGTATGGAAGATTTGGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTTATTCCTCAAGAAAAAACGGAAGAATTTTTCTATTCCGTGATGGACGAACTTGATTTACCAGATAACT
TCAAAAATAGTGGCATGTTGAGTTTTCGAGTGACACCTAAGAAAGATCGATTAGATGTTTTTGTAACCAAGTCTGAAATT
GATAAGGATTTAAACTTTGATGATTTAGCAGCCTTGGGTGATGTCTCTCAAATGTCTCCGGATGAATTCTTTAAGACATT
AGAAAAATCAATGTTGGAGAAGGGAGACACTGAAGCTCACGAGAAGTTAAAACAAATGGAAGAAATCGTGGAATCTGCGA
TGACAGAGCAAGCATCAGAAGCAGACTTAGCAGATGAATCGACTGAAGATAATGCTGAACAAGACAATTATACGCACTAT
GTGTTACAGTTTCCCATGCTGAAAGATGCCGTTGCTTTTTCAAAAGCGATTGACTTTGATATAGAAGCATCAGAACTGTA
TAAATTCAATGGCAGTTACTATATTACTATCTTGGTCAGTCTAGAAAATAAGCCCGCTTATTATGCCGACTTGGTTCACG
CTCGCTTGTTGGAGCACAGTCGTGGTGGTCAAAAAACAAGAGCCTATCTGCAAGAGCATGGCGTCCGTTTGCTTGAAGGC
TATGCAGTGGCTGATTTAGAAGGTATCAAGGTGGTCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

59.839

98.81

0.591
  mecA Streptococcus thermophilus LMD-9

55.906

100

0.563
  mecA Streptococcus thermophilus LMG 18311

55.118

100

0.556
  mecA Streptococcus pneumoniae Rx1

50

100

0.5
  mecA Streptococcus pneumoniae D39

50

100

0.5
  mecA Streptococcus pneumoniae R6

50

100

0.5
  mecA Streptococcus pneumoniae TIGR4

49.603

100

0.496

Multiple sequence alignment