Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   DQM54_RS10445 Genome accession   NZ_LS483375
Coordinates   2104703..2106061 (-) Length   452 a.a.
NCBI ID   WP_111724244.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC3165     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2099703..2111061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM54_RS10430 (NCTC3165_02076) - 2100178..2101371 (-) 1194 WP_111724241.1 ATP-grasp domain-containing protein -
  DQM54_RS10435 (NCTC3165_02077) purD 2101431..2102690 (-) 1260 WP_111724242.1 phosphoribosylamine--glycine ligase -
  DQM54_RS10440 (NCTC3165_02078) lytF 2102935..2104584 (+) 1650 WP_111724243.1 GBS Bsp-like repeat-containing protein Regulator
  DQM54_RS10445 (NCTC3165_02079) comB 2104703..2106061 (-) 1359 WP_111724244.1 competence pheromone export protein ComB Regulator
  DQM54_RS10450 (NCTC3165_02080) comA 2106071..2108224 (-) 2154 WP_111724245.1 peptide cleavage/export ABC transporter ComA Regulator
  DQM54_RS10455 (NCTC3165_02081) - 2108926..2109135 (-) 210 WP_111724246.1 hypothetical protein -
  DQM54_RS10465 (NCTC3165_02083) - 2109997..2110500 (-) 504 WP_111724247.1 hypothetical protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 49835.12 Da        Isoelectric Point: 6.1758

>NTDB_id=1021344 DQM54_RS10445 WP_111724244.1 2104703..2106061(-) (comB) [Streptococcus gordonii strain NCTC3165]
MNEQFLESAEFYQKRYHNFASCLIVPSLILLVFLVGFSMLAKKEITISSRASVEASRVLAQIQSTSNQAIIANHLAENKE
VKKGDLLIQYAVEGEGAQEQKFSSQLDLLKDQKGKLETLRSSLESGRNQFTEPDSYGYEQSFKDYQNQVASMTSSVNQQN
ATIASQNAAASQSQAELGGVISDVDSKLNDYRNLKNAIQSGVGIDASHPLYSLYQSYRDQLSLAEDKTTAQSQIVAQLDG
QISQLEATAATYRVQYAGAGAQQAYASNLSSQLASLKAQYLVKVGQELTTLTQQILEAESNLKLQETVSKRGQILAEMDG
LLHLNPEVQGSTLVAEGTALAQIYPKITSERKIKIVTYVSSKDVSTIKNGDKVRFITADDANKQMILTSQISSIDANATQ
TKQGNFFKVECEMAVSKDQAKKLRYGLEGKFVMVTGQKTYFSYYMEKFFNLG

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=1021344 DQM54_RS10445 WP_111724244.1 2104703..2106061(-) (comB) [Streptococcus gordonii strain NCTC3165]
ATGAATGAACAATTTTTAGAAAGTGCAGAGTTTTATCAGAAACGTTATCATAATTTTGCTAGTTGTTTAATTGTGCCAAG
TCTTATTTTACTAGTATTTCTAGTTGGTTTTTCCATGCTGGCTAAAAAGGAAATTACGATTTCTAGCCGTGCTTCTGTAG
AAGCTAGCCGAGTGCTAGCTCAGATTCAGTCGACTAGTAACCAGGCTATCATTGCGAATCATTTGGCAGAAAATAAGGAG
GTCAAAAAAGGAGACCTGTTAATTCAGTATGCAGTAGAAGGAGAGGGAGCTCAGGAACAGAAGTTTTCCAGCCAGCTTGA
CTTACTCAAAGATCAAAAGGGCAAACTAGAAACTTTGCGTTCCAGTTTAGAAAGCGGGCGTAATCAATTCACTGAGCCAG
ATAGTTATGGCTACGAACAAAGCTTTAAAGACTACCAGAATCAAGTAGCGAGTATGACTAGTTCTGTGAATCAGCAAAAT
GCTACGATTGCTTCACAAAATGCAGCGGCCAGTCAGTCTCAGGCGGAACTGGGCGGTGTTATCAGTGATGTGGATAGCAA
ACTAAATGACTATCGAAACTTGAAAAATGCCATTCAAAGTGGGGTAGGTATAGACGCATCGCACCCTCTTTACTCCTTGT
ATCAGTCCTATCGTGATCAGTTGAGTTTGGCAGAGGATAAGACTACGGCTCAAAGTCAGATTGTAGCTCAATTAGATGGG
CAAATTTCTCAATTAGAAGCAACAGCTGCGACTTATCGTGTCCAATATGCTGGTGCAGGCGCTCAACAAGCCTATGCTAG
CAATTTATCTAGTCAGTTGGCTTCACTGAAAGCTCAGTATCTGGTCAAGGTAGGACAAGAATTGACCACTCTGACTCAGC
AAATCTTGGAAGCCGAGAGCAATCTTAAACTTCAAGAAACAGTCTCTAAGCGAGGTCAGATTTTGGCTGAAATGGATGGC
TTGCTTCACTTAAATCCAGAAGTACAAGGATCTACTCTAGTGGCAGAAGGAACAGCTTTGGCTCAGATTTATCCTAAAAT
CACCAGTGAACGAAAAATCAAAATTGTCACATATGTCTCTTCCAAGGATGTATCTACTATTAAAAATGGAGATAAGGTGC
GCTTTATCACAGCTGATGATGCTAACAAACAAATGATTTTGACATCCCAAATTTCCAGTATTGACGCCAATGCTACTCAA
ACCAAACAAGGAAATTTCTTTAAAGTAGAATGCGAAATGGCTGTTAGTAAAGATCAAGCTAAGAAGCTCCGCTATGGCTT
GGAAGGTAAATTCGTCATGGTAACTGGGCAAAAGACTTATTTCAGCTATTATATGGAGAAGTTTTTTAATCTTGGTTGA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(314-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

98.23

100

0.982
  comB Streptococcus pneumoniae Rx1

56.222

99.558

0.56
  comB Streptococcus pneumoniae D39

56.222

99.558

0.56
  comB Streptococcus pneumoniae R6

56.222

99.558

0.56
  comB Streptococcus mitis NCTC 12261

56

99.558

0.558
  comB Streptococcus pneumoniae TIGR4

55.778

99.558

0.555
  comB Streptococcus mitis SK321

55.333

99.558

0.551