Detailed information
Bioinformatically predicted
Overview
| Name | vicR | Type | Regulator |
| Locus tag | ABZ559_RS07855 | Genome accession | NZ_CP160400 |
| Coordinates | 1541025..1541735 (-) | Length | 236 a.a. |
| NCBI ID | WP_018375892.1 | Uniprot ID | - |
| Organism | Streptococcus sp. ZY19097 | ||
| Function | repress comCDE expression; repress comX expression (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1518839..1547226 | 1541025..1541735 | within | 0 |
Gene organization within MGE regions
Location: 1518839..1547226
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABZ559_RS07725 (ABZ559_07725) | - | 1518839..1518982 (-) | 144 | WP_367005817.1 | hypothetical protein | - |
| ABZ559_RS07730 (ABZ559_07730) | - | 1518985..1519347 (-) | 363 | WP_367005819.1 | excisionase | - |
| ABZ559_RS07735 (ABZ559_07735) | - | 1519598..1520800 (-) | 1203 | WP_367005822.1 | IS110 family transposase | - |
| ABZ559_RS07740 (ABZ559_07740) | - | 1521225..1521644 (-) | 420 | WP_367005825.1 | ORF6C domain-containing protein | - |
| ABZ559_RS07745 (ABZ559_07745) | - | 1521641..1522567 (-) | 927 | WP_367005827.1 | DUF3102 domain-containing protein | - |
| ABZ559_RS07750 (ABZ559_07750) | - | 1522560..1522763 (-) | 204 | WP_367005830.1 | helix-turn-helix transcriptional regulator | - |
| ABZ559_RS07755 (ABZ559_07755) | - | 1522931..1523107 (+) | 177 | Protein_1523 | DUF1508 domain-containing protein | - |
| ABZ559_RS07760 (ABZ559_07760) | - | 1523280..1523798 (+) | 519 | WP_367005833.1 | hypothetical protein | - |
| ABZ559_RS07765 (ABZ559_07765) | - | 1524035..1525237 (-) | 1203 | WP_367005835.1 | IS110 family transposase | - |
| ABZ559_RS07770 (ABZ559_07770) | - | 1525392..1525724 (-) | 333 | WP_367005837.1 | hypothetical protein | - |
| ABZ559_RS07775 (ABZ559_07775) | - | 1525790..1525987 (-) | 198 | WP_367005839.1 | XRE family transcriptional regulator | - |
| ABZ559_RS07780 (ABZ559_07780) | - | 1526068..1526388 (+) | 321 | WP_367005842.1 | hypothetical protein | - |
| ABZ559_RS07785 (ABZ559_07785) | - | 1526733..1526939 (-) | 207 | WP_367005845.1 | hypothetical protein | - |
| ABZ559_RS07790 (ABZ559_07790) | - | 1527104..1527862 (+) | 759 | WP_367005848.1 | XRE family transcriptional regulator | - |
| ABZ559_RS07795 (ABZ559_07795) | - | 1528067..1528918 (+) | 852 | WP_367005850.1 | Abi family protein | - |
| ABZ559_RS07800 (ABZ559_07800) | - | 1529120..1530176 (+) | 1057 | Protein_1532 | IS630 family transposase | - |
| ABZ559_RS07805 (ABZ559_07805) | - | 1530299..1531402 (+) | 1104 | WP_367007646.1 | tyrosine-type recombinase/integrase | - |
| ABZ559_RS07810 (ABZ559_07810) | eno | 1531379..1532677 (-) | 1299 | WP_018375899.1 | surface-displayed alpha-enolase | - |
| ABZ559_RS07815 (ABZ559_07815) | - | 1532884..1533333 (+) | 450 | WP_367005853.1 | DUF1694 domain-containing protein | - |
| ABZ559_RS07820 (ABZ559_07820) | - | 1533489..1534493 (-) | 1005 | WP_367005855.1 | sugar transferase | - |
| ABZ559_RS07825 (ABZ559_07825) | - | 1534885..1535988 (-) | 1104 | WP_367005858.1 | glycerate kinase | - |
| ABZ559_RS07830 (ABZ559_07830) | - | 1536046..1536546 (+) | 501 | WP_018375895.1 | NUDIX domain-containing protein | - |
| ABZ559_RS07835 (ABZ559_07835) | - | 1536753..1536940 (+) | 188 | Protein_1539 | IS110 family transposase | - |
| ABZ559_RS07840 (ABZ559_07840) | - | 1537180..1538382 (-) | 1203 | WP_367005859.1 | IS110 family transposase | - |
| ABZ559_RS07845 (ABZ559_07845) | vicX | 1538861..1539670 (-) | 810 | WP_273403598.1 | MBL fold metallo-hydrolase | Regulator |
| ABZ559_RS07850 (ABZ559_07850) | vicK | 1539671..1541032 (-) | 1362 | WP_277291577.1 | cell wall metabolism sensor histidine kinase VicK | Regulator |
| ABZ559_RS07855 (ABZ559_07855) | vicR | 1541025..1541735 (-) | 711 | WP_018375892.1 | response regulator YycF | Regulator |
| ABZ559_RS07860 (ABZ559_07860) | - | 1541996..1542760 (+) | 765 | WP_273403603.1 | amino acid ABC transporter ATP-binding protein | - |
| ABZ559_RS07865 (ABZ559_07865) | - | 1542773..1543576 (+) | 804 | WP_367005861.1 | transporter substrate-binding domain-containing protein | - |
| ABZ559_RS07870 (ABZ559_07870) | - | 1543591..1544289 (+) | 699 | WP_273403609.1 | amino acid ABC transporter permease | - |
| ABZ559_RS07875 (ABZ559_07875) | - | 1544302..1544949 (+) | 648 | WP_018375888.1 | amino acid ABC transporter permease | - |
| ABZ559_RS07880 (ABZ559_07880) | - | 1545373..1546429 (-) | 1057 | Protein_1548 | IS630 family transposase | - |
| ABZ559_RS07885 (ABZ559_07885) | - | 1546594..1547226 (-) | 633 | WP_273403614.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 236 a.a. Molecular weight: 27122.04 Da Isoelectric Point: 4.7662
>NTDB_id=1020942 ABZ559_RS07855 WP_018375892.1 1541025..1541735(-) (vicR) [Streptococcus sp. ZY19097]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGREALEKFKEEEPDLIVLDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAESNNANNISEISVGDLQILPDAFVAKKHGEEIE
LTHREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDVPSRPEYILTRRGVGYFMKVYD
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGREALEKFKEEEPDLIVLDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAESNNANNISEISVGDLQILPDAFVAKKHGEEIE
LTHREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDVPSRPEYILTRRGVGYFMKVYD
Nucleotide
Download Length: 711 bp
>NTDB_id=1020942 ABZ559_RS07855 WP_018375892.1 1541025..1541735(-) (vicR) [Streptococcus sp. ZY19097]
ATGAAAAAGATTCTAATCGTAGATGACGAAAAACCAATTTCAGATATTATTAAGTTTAATTTGACCAAGGAAGGTTACGA
TACCGTGACCGCTTTTGATGGTCGTGAAGCTTTGGAGAAATTTAAAGAAGAAGAGCCAGACTTAATCGTCTTGGATTTAA
TGTTACCAGAGCTTGATGGTTTGGAAGTGGCCAAAGAAGTTCGAAAAACTAGCCATATTCCAATCATTATGCTTTCTGCC
AAAGATAGTGAGTTTGATAAAGTTATTGGACTTGAAATTGGTGCAGATGATTATGTGACTAAACCTTTTTCAAACCGTGA
ATTGTTAGCGCGTGTGAAGGCTCATTTGCGTCGAACAGAGACAATTGAGACAGCCGTTGCAGAAAGCAATAACGCTAATA
ATATCTCAGAAATTAGCGTGGGAGATTTGCAAATTTTACCAGACGCTTTTGTTGCAAAGAAGCATGGTGAGGAAATTGAG
TTAACTCATCGTGAATTTGAGTTGCTCTTCCATTTGGCGACTCATATGGGGCAAGTAATGACACGTGAGCACTTACTTGA
AACTGTCTGGGGTTACGATTATTTTGGAGATGTGCGTACTGTTGATGTGACTGTTCGACGTTTACGTGAAAAAATTGAAG
ATGTCCCTAGTCGCCCAGAGTATATTTTGACTCGTCGTGGTGTGGGCTATTTTATGAAAGTATATGACTAA
ATGAAAAAGATTCTAATCGTAGATGACGAAAAACCAATTTCAGATATTATTAAGTTTAATTTGACCAAGGAAGGTTACGA
TACCGTGACCGCTTTTGATGGTCGTGAAGCTTTGGAGAAATTTAAAGAAGAAGAGCCAGACTTAATCGTCTTGGATTTAA
TGTTACCAGAGCTTGATGGTTTGGAAGTGGCCAAAGAAGTTCGAAAAACTAGCCATATTCCAATCATTATGCTTTCTGCC
AAAGATAGTGAGTTTGATAAAGTTATTGGACTTGAAATTGGTGCAGATGATTATGTGACTAAACCTTTTTCAAACCGTGA
ATTGTTAGCGCGTGTGAAGGCTCATTTGCGTCGAACAGAGACAATTGAGACAGCCGTTGCAGAAAGCAATAACGCTAATA
ATATCTCAGAAATTAGCGTGGGAGATTTGCAAATTTTACCAGACGCTTTTGTTGCAAAGAAGCATGGTGAGGAAATTGAG
TTAACTCATCGTGAATTTGAGTTGCTCTTCCATTTGGCGACTCATATGGGGCAAGTAATGACACGTGAGCACTTACTTGA
AACTGTCTGGGGTTACGATTATTTTGGAGATGTGCGTACTGTTGATGTGACTGTTCGACGTTTACGTGAAAAAATTGAAG
ATGTCCCTAGTCGCCCAGAGTATATTTTGACTCGTCGTGGTGTGGGCTATTTTATGAAAGTATATGACTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| vicR | Streptococcus mutans UA159 |
88.983 |
100 |
0.89 |
| micA | Streptococcus pneumoniae Cp1015 |
77.682 |
98.729 |
0.767 |
| covR | Lactococcus lactis subsp. lactis strain DGCC12653 |
47.414 |
98.305 |
0.466 |
| covR | Streptococcus salivarius strain HSISS4 |
46.552 |
98.305 |
0.458 |
| scnR | Streptococcus mutans UA159 |
37.975 |
100 |
0.381 |