Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ABZ559_RS03105 Genome accession   NZ_CP160400
Coordinates   610037..610777 (+) Length   246 a.a.
NCBI ID   WP_367007204.1    Uniprot ID   -
Organism   Streptococcus sp. ZY19097     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 605037..615777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABZ559_RS03080 (ABZ559_03080) mutY 605532..606674 (-) 1143 WP_367007201.1 A/G-specific adenine glycosylase -
  ABZ559_RS03085 (ABZ559_03085) - 606947..607432 (-) 486 WP_367007202.1 LemA family protein -
  ABZ559_RS03090 (ABZ559_03090) rpsF 608586..608876 (+) 291 WP_018376394.1 30S ribosomal protein S6 -
  ABZ559_RS03095 (ABZ559_03095) ssbA 608888..609397 (+) 510 WP_367007203.1 single-stranded DNA-binding protein Machinery gene
  ABZ559_RS03100 (ABZ559_03100) rpsR 609435..609674 (+) 240 WP_000068664.1 30S ribosomal protein S18 -
  ABZ559_RS03105 (ABZ559_03105) comE/blpR 610037..610777 (+) 741 WP_367007204.1 LytTR family DNA-binding domain-containing protein Regulator
  ABZ559_RS03110 (ABZ559_03110) - 610774..612081 (+) 1308 WP_367007205.1 GHKL domain-containing protein -
  ABZ559_RS03115 (ABZ559_03115) - 612389..612454 (+) 66 Protein_600 YSIRK-type signal peptide-containing protein -
  ABZ559_RS03120 (ABZ559_03120) - 612478..612591 (+) 114 WP_367007616.1 SH3 domain-containing protein -
  ABZ559_RS03125 (ABZ559_03125) - 612607..613281 (+) 675 WP_367007206.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28662.01 Da        Isoelectric Point: 6.8417

>NTDB_id=1020923 ABZ559_RS03105 WP_367007204.1 610037..610777(+) (comE/blpR) [Streptococcus sp. ZY19097]
MLNIFVLEDDLIQQSRIENAINKALVKNKWKVRAINISGKPEQLLEAAKERGCHQLFFLDIQIDKDDKRGFKMAQQIRSN
DPQAVIVFVTTHSEFLPLTFQYKVAALDFIDKLADEEEYVGRIESAIEVALSHMGNSVAEDSFTFETSQAVIQVPFHKIL
YFETSETIHKVILHTKNEQIEFYGRLSQIEKVDERLYKCHKSFVVNPENITKIDKESGIVYFENGERCFVSKLKRKKLIE
KMREMR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=1020923 ABZ559_RS03105 WP_367007204.1 610037..610777(+) (comE/blpR) [Streptococcus sp. ZY19097]
ATGTTAAATATTTTTGTTTTAGAAGATGATCTTATCCAACAATCTCGGATAGAAAATGCCATAAATAAAGCACTTGTAAA
GAACAAGTGGAAAGTGCGTGCGATTAATATCTCTGGGAAACCAGAACAATTATTAGAGGCTGCAAAAGAACGAGGTTGTC
ATCAATTATTTTTCCTTGATATTCAAATTGATAAAGATGATAAAAGGGGCTTCAAAATGGCTCAGCAAATTAGGAGTAAC
GACCCGCAAGCAGTTATTGTATTCGTAACAACGCATTCGGAGTTTTTACCCCTAACCTTTCAATACAAGGTCGCGGCTTT
GGATTTTATAGACAAATTAGCTGATGAAGAAGAGTATGTAGGACGCATAGAGTCAGCTATTGAAGTAGCTTTAAGTCATA
TGGGAAATAGCGTAGCTGAAGACTCTTTTACATTTGAAACCTCTCAAGCTGTTATTCAAGTTCCTTTTCATAAAATCCTT
TATTTTGAGACATCCGAGACAATTCATAAGGTTATCTTGCACACTAAAAATGAACAGATTGAATTTTATGGGCGATTATC
GCAAATTGAAAAAGTAGATGAGCGGCTTTACAAATGCCATAAATCGTTTGTTGTTAATCCAGAAAATATCACTAAAATAG
ACAAAGAATCTGGAATAGTATACTTTGAAAACGGAGAGAGGTGCTTTGTCTCCAAATTAAAACGGAAAAAATTGATTGAG
AAAATGAGGGAGATGCGGTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.301

97.154

0.508
  comE/comE1 Streptococcus equinus JB1

48.56

98.78

0.48
  comE/comE2 Streptococcus equinus JB1

38.211

100

0.382
  agrA Staphylococcus aureus N315

37.603

98.374

0.37

Multiple sequence alignment