Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ABZ559_RS00760 Genome accession   NZ_CP160400
Coordinates   157414..158163 (+) Length   249 a.a.
NCBI ID   WP_367006858.1    Uniprot ID   -
Organism   Streptococcus sp. ZY19097     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 152414..163163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABZ559_RS00735 (ABZ559_00735) - 152505..152624 (-) 120 WP_018374973.1 putative metal homeostasis protein -
  ABZ559_RS00740 (ABZ559_00740) - 153213..153812 (-) 600 WP_317335338.1 VanZ family protein -
  ABZ559_RS00745 (ABZ559_00745) - 153938..154678 (-) 741 WP_317335337.1 amino acid ABC transporter ATP-binding protein -
  ABZ559_RS00750 (ABZ559_00750) - 154678..156237 (-) 1560 WP_367006856.1 ABC transporter substrate-binding protein/permease -
  ABZ559_RS00755 (ABZ559_00755) - 156446..157285 (+) 840 WP_273415228.1 undecaprenyl-diphosphate phosphatase -
  ABZ559_RS00760 (ABZ559_00760) mecA 157414..158163 (+) 750 WP_367006858.1 adaptor protein MecA Regulator
  ABZ559_RS00765 (ABZ559_00765) - 158165..159325 (+) 1161 WP_367006859.1 MraY family glycosyltransferase -
  ABZ559_RS00770 (ABZ559_00770) sufC 159433..160203 (+) 771 WP_018374965.1 Fe-S cluster assembly ATPase SufC -
  ABZ559_RS00775 (ABZ559_00775) sufD 160240..161502 (+) 1263 WP_367006861.1 Fe-S cluster assembly protein SufD -
  ABZ559_RS00780 (ABZ559_00780) - 161504..162736 (+) 1233 WP_026217069.1 cysteine desulfurase -
  ABZ559_RS00785 (ABZ559_00785) sufU 162723..163163 (+) 441 WP_018374962.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 28951.59 Da        Isoelectric Point: 4.1534

>NTDB_id=1020906 ABZ559_RS00760 WP_367006858.1 157414..158163(+) (mecA) [Streptococcus sp. ZY19097]
MEMKQISETTLKITISMEDLEEHGMELKDFLLPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRIDVFVTKSEL
NKDLNFEDLSEFGDVSNMSPEDFFKTLEQSMRSKGDTEAHEKLEKIEEMVEAAISETQADEKLSEEEEINPTEYVHYVLD
FANLEDVISFSKAIDFEVEASELYKQADRYHMTILLSLIDKPSYYANVMYARLLEHATPGTKTRAYLQEHGVQLLLENAV
ENLRLIELV

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1020906 ABZ559_RS00760 WP_367006858.1 157414..158163(+) (mecA) [Streptococcus sp. ZY19097]
ATGGAAATGAAACAAATTAGCGAAACAACGCTGAAGATTACGATTAGTATGGAAGACTTGGAAGAACATGGTATGGAGCT
TAAAGATTTCTTGTTACCACAGGAGAAAACTGAGGAATTTTTCTATACAGTAATGGATGAACTTGATCTCCCTGACAATT
TTAAAAATAGCGGTATGTTGAGCTTTCGAGTAACACCACGCAAGGATCGCATTGATGTCTTTGTGACCAAGTCTGAACTG
AATAAGGATTTGAATTTTGAAGATTTGTCTGAGTTTGGGGATGTTTCCAACATGTCTCCAGAAGATTTTTTCAAGACTTT
AGAGCAATCTATGCGCTCCAAGGGTGACACTGAGGCGCATGAAAAGCTTGAAAAAATTGAAGAAATGGTGGAAGCGGCTA
TCAGTGAAACTCAGGCAGATGAAAAGTTGTCTGAAGAAGAGGAAATCAACCCTACAGAGTATGTTCATTACGTCTTGGAT
TTTGCAAACTTGGAGGATGTTATCTCCTTTTCAAAGGCTATTGATTTTGAAGTAGAGGCTTCTGAACTTTATAAGCAAGC
TGATCGTTACCATATGACTATTTTGCTTAGTTTGATTGACAAACCAAGTTATTATGCTAATGTGATGTACGCTCGTCTAT
TGGAGCACGCCACTCCTGGAACGAAGACACGTGCCTATTTACAAGAACATGGTGTACAACTCCTACTAGAGAATGCTGTT
GAAAATTTACGTTTAATTGAATTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.073

98.795

0.663
  mecA Streptococcus thermophilus LMD-9

60.816

98.394

0.598
  mecA Streptococcus thermophilus LMG 18311

60

98.394

0.59
  mecA Streptococcus pneumoniae Rx1

49.004

100

0.494
  mecA Streptococcus pneumoniae D39

49.004

100

0.494
  mecA Streptococcus pneumoniae R6

49.004

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.004

100

0.494

Multiple sequence alignment