Detailed information NTG1020546

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: DQM58_RS02780
• Genome accession: NZ_LS483363
• Coordinates: 505691..507844 (-)
• Length: 717 a.a.
• NCBI ID: WP_003062135.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 500691..512844

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM58_RS02760 (NCTC9414_00556)	comE/blpR	501955..502704 (+)	750	WP_046159788.1	response regulator transcription factor	Regulator
DQM58_RS02765 (NCTC9414_00557)	-	502705..504039 (+)	1335	WP_111681558.1	GHKL domain-containing protein	-
DQM58_RS02770 (NCTC9414_00558)	-	504100..504225 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQM58_RS02775 (NCTC9414_00559)	-	504316..505680 (-)	1365	WP_012766651.1	bacteriocin secretion accessory protein	-
DQM58_RS02780 (NCTC9414_00560)	comA/nlmT	505691..507844 (-)	2154	WP_003062135.1	peptide cleavage/export ABC transporter	Regulator
DQM58_RS02785 (NCTC9414_00561)	-	508131..508358 (+)	228	WP_002992018.1	Blp family class II bacteriocin	-
DQM58_RS02790 (NCTC9414_00562)	-	508371..508571 (+)	201	WP_003060803.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
DQM58_RS02800 (NCTC9414_00564)	-	508866..509060 (+)	195	WP_002990768.1	hypothetical protein	-
DQM58_RS02805 (NCTC9414_00565)	-	509108..509389 (+)	282	WP_046159519.1	hypothetical protein	-
DQM58_RS02810 (NCTC9414_00566)	-	509583..509993 (+)	411	WP_012766654.1	hypothetical protein	-
DQM58_RS02815	-	510240..510487 (+)	248	Protein_486	hypothetical protein	-
DQM58_RS11305	-	510461..510586 (+)	126	WP_324291849.1	CPBP family glutamic-type intramembrane protease	-
DQM58_RS02820	-	510561..510767 (+)	207	WP_161806819.1	CPBP family intramembrane glutamic endopeptidase	-
DQM58_RS02825 (NCTC9414_00567)	-	511150..511914 (+)	765	WP_172452853.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80558.51 Da
• Isoelectric Point: 7.0109

>NTDB_id=1020546 DQM58_RS02780 WP_003062135.1 505691..507844(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS

Nucleotide

• Length: 2154 bp

>NTDB_id=1020546 DQM58_RS02780 WP_003062135.1 505691..507844(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTTTTTGCAACTCGCAGAACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTTCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGTA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.867	99.721	0.727
comA	Streptococcus mitis NCTC 12261	67.647	99.582	0.674
comA	Streptococcus mitis SK321	67.227	99.582	0.669
comA	Streptococcus pneumoniae Rx1	67.227	99.582	0.669
comA	Streptococcus pneumoniae D39	67.227	99.582	0.669
comA	Streptococcus pneumoniae R6	67.227	99.582	0.669
comA	Streptococcus pneumoniae TIGR4	66.947	99.582	0.667
comA	Streptococcus gordonii str. Challis substr. CH1	66.017	100	0.661