Detailed information NTG1018529

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: DQL34_RS01285
• Genome accession: NZ_LS483339
• Coordinates: 233860..234609 (+)
• Length: 249 a.a.
• NCBI ID: WP_100273348.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain NCTC12958
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 228860..239609

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL34_RS11245 (NCTC12958_00264)	-	229425..229595 (+)	171	WP_167740656.1	hypothetical protein	-
DQL34_RS01260	-	229682..229789 (+)	108	WP_081247985.1	LPXTG cell wall anchor domain-containing protein	-
DQL34_RS01265 (NCTC12958_00265)	-	229876..230616 (-)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
DQL34_RS01270 (NCTC12958_00266)	-	230616..232166 (-)	1551	WP_011680665.1	ABC transporter substrate-binding protein/permease	-
DQL34_RS01275 (NCTC12958_00267)	-	232369..233223 (+)	855	WP_011680666.1	undecaprenyl-diphosphate phosphatase	-
DQL34_RS01280	-	233275..233583 (-)	309	WP_306496352.1	DUF3021 family protein	-
DQL34_RS01285 (NCTC12958_00268)	mecA	233860..234609 (+)	750	WP_100273348.1	adaptor protein MecA	Regulator
DQL34_RS01290 (NCTC12958_00269)	-	234613..235770 (+)	1158	WP_100262326.1	glycosyltransferase family 4 protein	-
DQL34_RS01295 (NCTC12958_00270)	sufC	235931..236701 (+)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
DQL34_RS01300 (NCTC12958_00271)	sufD	236738..238000 (+)	1263	WP_011680669.1	Fe-S cluster assembly protein SufD	-
DQL34_RS01305 (NCTC12958_00272)	-	238054..239286 (+)	1233	WP_046206385.1	cysteine desulfurase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29116.68 Da
• Isoelectric Point: 4.0182

>NTDB_id=1018529 DQL34_RS01285 WP_100273348.1 233860..234609(+) (mecA) [Streptococcus thermophilus strain NCTC12958]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEELEKTLKEVDETMTDPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=1018529 DQL34_RS01285 WP_100273348.1 233860..234609(+) (mecA) [Streptococcus thermophilus strain NCTC12958]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTACCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCTTGAAAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGATCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAACTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterProScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMD-9	98.394	100	0.984
mecA	Streptococcus thermophilus LMG 18311	97.59	100	0.976
mecA	Streptococcus mutans UA159	59.016	97.992	0.578
mecA	Streptococcus pneumoniae Rx1	46.988	100	0.47
mecA	Streptococcus pneumoniae D39	46.988	100	0.47
mecA	Streptococcus pneumoniae R6	46.988	100	0.47
mecA	Streptococcus pneumoniae TIGR4	46.988	100	0.47