Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   DQL34_RS01120 Genome accession   NZ_LS483339
Coordinates   198832..200193 (-) Length   453 a.a.
NCBI ID   WP_111679175.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain NCTC12958     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 193832..205193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS01100 (NCTC12958_00224) - 196096..196437 (+) 342 WP_024404826.1 LytR/AlgR family response regulator transcription factor -
  DQL34_RS01105 (NCTC12958_00225) comE/blpR 196439..197179 (+) 741 WP_111679174.1 response regulator transcription factor Regulator
  DQL34_RS01110 (NCTC12958_00226) - 197190..198530 (+) 1341 WP_039671036.1 sensor histidine kinase -
  DQL34_RS01115 (NCTC12958_00227) - 198578..198733 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQL34_RS01120 (NCTC12958_00228) comB 198832..200193 (-) 1362 WP_111679175.1 bacteriocin secretion accessory protein Regulator
  DQL34_RS01125 (NCTC12958_00229) - 200205..202359 (-) 2155 Protein_175 peptide cleavage/export ABC transporter -
  DQL34_RS01130 (NCTC12958_00231) - 202657..202914 (+) 258 WP_039671027.1 Blp family class II bacteriocin -
  DQL34_RS01135 (NCTC12958_00232) - 202931..203110 (+) 180 WP_111679177.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DQL34_RS01140 - 203712..205062 (+) 1351 Protein_178 IS3 family transposase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 50325.41 Da        Isoelectric Point: 5.2958

>NTDB_id=1018528 DQL34_RS01120 WP_111679175.1 198832..200193(-) (comB) [Streptococcus thermophilus strain NCTC12958]
MNPNLFKSAEFYQRRYHNFATHLIVPLILLVGFLLTFSLFAQKEVTVTSRGEITPTTIIASIQSTSNNPITTNNLANNKL
VKKNELIIQYAETMESSQKQALETQLATLNRQKTGLETLKESLSQGTNLFTGEDEFGYINTFNNFITQSQDIELGISKTN
AEVSNQAALAGNTIAAIDTQINQIYHQIAEYEELRQAITNRQTSLSADNPHQATLNNFLAQSQQDSQTGLTDQYLSQINQ
SISGLESSIASLNIQRAGTGSVATYDNSFVTKVEVLRTQFLQSASQQLTTLETQITELVAQLEQASVRLENNTITAPETG
VIHLNSEFEGKSLIPSGSEIAQIYPNINQTKEFLITYYVTSEHVALLKEKQDVRLSLEKVGNQSITVVGKIKSIDKTATK
TEEGNLFKVTALAQLSDKHSDVIQYGLQGRVTSIIAKKTYFDYYKDKILSNHD

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=1018528 DQL34_RS01120 WP_111679175.1 198832..200193(-) (comB) [Streptococcus thermophilus strain NCTC12958]
ATGAACCCTAATTTGTTCAAAAGTGCTGAATTTTACCAGCGGCGCTACCATAATTTTGCGACACACTTAATTGTCCCCTT
GATATTATTAGTCGGCTTTCTTCTAACCTTCTCCCTTTTTGCCCAAAAGGAGGTTACCGTCACATCAAGAGGTGAAATTA
CTCCGACGACAATCATCGCTTCCATCCAATCCACCAGCAATAACCCTATCACAACCAATAATCTAGCCAATAACAAGCTG
GTTAAAAAGAATGAGCTCATCATCCAATACGCTGAAACTATGGAGAGTTCCCAAAAACAAGCCCTTGAAACCCAGCTAGC
CACTCTAAATAGACAGAAAACTGGACTTGAAACCCTCAAAGAAAGCCTGTCACAGGGAACGAACCTCTTTACAGGGGAGG
ACGAATTTGGCTATATCAATACTTTTAACAACTTTATCACCCAGTCACAGGACATCGAACTAGGAATTTCCAAAACCAAT
GCAGAGGTGAGTAACCAGGCCGCCCTAGCAGGTAATACCATTGCTGCGATTGACACGCAAATCAATCAAATCTATCACCA
AATAGCAGAATACGAGGAGCTTCGTCAAGCCATTACCAATAGACAGACCAGTTTATCAGCTGACAATCCACACCAAGCCA
CCTTAAACAATTTCTTAGCCCAATCCCAACAAGACTCCCAGACAGGATTAACTGATCAATACCTTTCTCAAATCAACCAA
AGTATCTCAGGGCTAGAATCATCCATAGCTAGTCTGAACATCCAACGAGCTGGAACTGGCTCTGTTGCAACCTATGATAA
CAGCTTTGTAACAAAGGTTGAGGTCCTAAGAACACAGTTTTTACAATCGGCCTCTCAGCAGCTGACCACCCTTGAAACGC
AAATCACAGAGCTAGTGGCACAGCTAGAGCAAGCATCCGTCCGACTAGAAAACAATACCATTACAGCTCCTGAAACAGGG
GTAATCCATCTCAATAGTGAGTTTGAAGGAAAGTCTTTGATTCCAAGCGGTAGTGAAATCGCTCAGATTTACCCCAATAT
CAATCAAACCAAAGAATTCCTCATTACTTACTACGTGACTTCAGAACATGTCGCCTTACTCAAAGAAAAACAAGACGTGC
GCCTGAGCTTAGAAAAAGTTGGCAACCAAAGCATCACTGTTGTTGGAAAAATTAAGTCTATCGATAAAACTGCTACTAAA
ACTGAGGAGGGGAATCTTTTCAAAGTTACTGCCTTGGCTCAACTATCCGACAAGCATAGCGACGTCATCCAGTACGGTCT
CCAGGGTCGAGTCACAAGTATCATTGCCAAGAAGACTTACTTTGATTACTACAAGGATAAAATTTTATCCAACCATGATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

38.444

99.338

0.382
  comB Streptococcus pneumoniae D39

38.444

99.338

0.382
  comB Streptococcus pneumoniae R6

38.444

99.338

0.382
  comB Streptococcus pneumoniae TIGR4

38.222

99.338

0.38
  comB Streptococcus mitis SK321

37.639

99.117

0.373
  comB Streptococcus mitis NCTC 12261

37.639

99.117

0.373