Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DQL34_RS01105 Genome accession   NZ_LS483339
Coordinates   196439..197179 (+) Length   246 a.a.
NCBI ID   WP_111679174.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain NCTC12958     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 191439..202179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS01075 (NCTC12958_00219) - 191732..192628 (+) 897 WP_111679168.1 restriction endonuclease -
  DQL34_RS01080 (NCTC12958_00220) - 192969..193331 (+) 363 WP_111679170.1 SAG1252 family conjugative relaxosome accessory protein -
  DQL34_RS01085 (NCTC12958_00221) - 193334..193699 (+) 366 WP_039671039.1 plasmid mobilization protein -
  DQL34_RS01090 (NCTC12958_00222) - 193686..195569 (+) 1884 WP_111679172.1 SAG1250 family conjugative relaxase -
  DQL34_RS01100 (NCTC12958_00224) - 196096..196437 (+) 342 WP_024404826.1 LytR/AlgR family response regulator transcription factor -
  DQL34_RS01105 (NCTC12958_00225) comE/blpR 196439..197179 (+) 741 WP_111679174.1 response regulator transcription factor Regulator
  DQL34_RS01110 (NCTC12958_00226) - 197190..198530 (+) 1341 WP_039671036.1 sensor histidine kinase -
  DQL34_RS01115 (NCTC12958_00227) - 198578..198733 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQL34_RS01120 (NCTC12958_00228) comB 198832..200193 (-) 1362 WP_111679175.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28890.15 Da        Isoelectric Point: 7.2201

>NTDB_id=1018527 DQL34_RS01105 WP_111679174.1 196439..197179(+) (comE/blpR) [Streptococcus thermophilus strain NCTC12958]
MNIFIIEDDFMQQARIEKIITKLLEKHNIVPKKFEISGKPHQLLQAIEEKGVHQLFFLDIEIKEDELKGLQVAKQIREID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGVTEFESRIEAALLHTHNKDNSAVSDDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLVQCHRSFAINPRNVVKVDRNEKQIYFPNGATCFISRQKLESTLAV
IDRLHR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=1018527 DQL34_RS01105 WP_111679174.1 196439..197179(+) (comE/blpR) [Streptococcus thermophilus strain NCTC12958]
ATGAATATCTTTATAATAGAAGATGATTTTATGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAAAACCTCATCAGCTACTTCAAGCAATAGAAGAAAAAGGAGTACATC
AGCTCTTCTTTTTAGATATTGAGATTAAGGAAGACGAACTAAAAGGACTTCAAGTCGCTAAACAAATTAGAGAGATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTATCTGCCTTGGA
CTATATTGACAAAGAGCTTGGAGTTACCGAATTTGAATCGCGAATAGAAGCAGCTTTACTTCATACTCACAATAAGGACA
ATAGCGCCGTATCGGATGATTCATTCTATTTTAAGTCCAAATATGCTCAAGTACAATACCCATTCAATGAAGTGTACTAC
ATCGAGACTTCTCCCCGCCCTCATCGTGTTATCCTTTATACCAAGACAGACCGAATGGAGTTCACAGCAAGTTTGTCAGA
CATTTTGAAACAAGATAAACGACTTGTACAATGTCATCGTTCGTTTGCAATCAATCCGAGGAATGTTGTTAAAGTGGATA
GAAATGAAAAACAGATCTACTTTCCTAATGGAGCCACCTGTTTTATTTCAAGGCAAAAGCTAGAATCAACTTTAGCTGTT
ATTGATAGACTGCATAGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.306

98.374

0.524
  comE/comE1 Streptococcus equinus JB1

41.841

97.154

0.407