Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   ABG809_RS08055 Genome accession   NZ_CP159893
Coordinates   1646684..1647409 (-) Length   241 a.a.
NCBI ID   WP_003101290.1    Uniprot ID   A0A3L8GIX6
Organism   Streptococcus iniae strain QMA0177     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641684..1652409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABG809_RS08020 (ABG809_08020) - 1641998..1642609 (-) 612 WP_016356076.1 phosphate ABC transporter ATP-binding protein -
  ABG809_RS08025 (ABG809_08025) pstA 1642612..1643427 (-) 816 WP_003101283.1 phosphate ABC transporter permease PstA -
  ABG809_RS08030 (ABG809_08030) pstC 1643420..1644283 (-) 864 WP_003101285.1 phosphate ABC transporter permease subunit PstC -
  ABG809_RS08035 (ABG809_08035) - 1644346..1645221 (-) 876 WP_003101287.1 substrate-binding domain-containing protein -
  ABG809_RS08040 (ABG809_08040) covS 1645375..1645626 (-) 252 WP_367561173.1 sensor histidine kinase Regulator
  ABG809_RS08045 (ABG809_08045) - 1645605..1645805 (-) 201 WP_367561174.1 hypothetical protein -
  ABG809_RS08050 (ABG809_08050) - 1645823..1646614 (-) 792 WP_367561175.1 histidine kinase dimerization/phospho-acceptor domain-containing protein -
  ABG809_RS08055 (ABG809_08055) vicR 1646684..1647409 (-) 726 WP_003101290.1 response regulator transcription factor Regulator
  ABG809_RS08060 (ABG809_08060) - 1647505..1647888 (-) 384 WP_003101292.1 VOC family protein -
  ABG809_RS08065 (ABG809_08065) - 1648081..1648224 (+) 144 WP_003101294.1 SPJ_0845 family protein -
  ABG809_RS08070 (ABG809_08070) - 1648224..1649129 (+) 906 WP_003101296.1 permease -
  ABG809_RS08075 (ABG809_08075) - 1649126..1649941 (+) 816 WP_003101297.1 TIGR03943 family protein -
  ABG809_RS08080 (ABG809_08080) - 1650013..1650639 (-) 627 WP_003101299.1 NAD(P)-dependent oxidoreductase -
  ABG809_RS08085 (ABG809_08085) - 1650777..1650926 (-) 150 WP_003101301.1 hypothetical protein -
  ABG809_RS08090 (ABG809_08090) - 1650926..1652302 (-) 1377 WP_003101303.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 28088.34 Da        Isoelectric Point: 5.1365

>NTDB_id=1016668 ABG809_RS08055 WP_003101290.1 1646684..1647409(-) (vicR) [Streptococcus iniae strain QMA0177]
MKKTVLLVDDEEHILRLLDYHLSKEGFSIDTATDGRSALKLAETESYDFILLDIMLPQLDGIEVCKRIRAKNSKTPIMMV
SAKGEEFDKVLALELGADDYMTKPFSPRELLARVKAILRRTGKDDSQQEEFGFADQRFLVNDLVIYPERNEVYKEQDLIS
LTPKEYELLMYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDDPKNPEMIKTIRGYGYQFKEMKDATK
S

Nucleotide


Download         Length: 726 bp        

>NTDB_id=1016668 ABG809_RS08055 WP_003101290.1 1646684..1647409(-) (vicR) [Streptococcus iniae strain QMA0177]
ATGAAAAAGACAGTTTTATTAGTAGACGACGAAGAGCACATCTTACGTTTATTAGACTATCATCTCAGCAAGGAAGGCTT
TAGTATTGACACAGCAACAGATGGCAGATCAGCACTAAAATTAGCTGAAACAGAAAGTTATGACTTCATTTTGTTAGACA
TCATGTTGCCCCAATTGGACGGTATTGAGGTCTGTAAACGTATCAGAGCTAAAAATAGTAAGACCCCTATTATGATGGTA
TCAGCTAAAGGGGAAGAATTTGACAAGGTCCTAGCCTTAGAACTAGGAGCTGATGATTACATGACAAAACCCTTTAGTCC
AAGGGAATTGCTGGCGCGTGTAAAAGCTATTTTAAGACGAACAGGAAAAGACGACAGCCAACAAGAAGAGTTTGGCTTCG
CTGACCAGCGATTCTTGGTCAATGACTTGGTCATTTACCCTGAAAGAAATGAAGTTTACAAAGAGCAAGACTTGATTTCC
TTAACCCCAAAAGAGTATGAACTGTTAATGTATTTAGTCAAACATCCCAATATGACCTTAACAAGAGAACGACTTTTAGA
ACGGATTTGGGGGTATGACTTTGGCCAAGAAACACGTTTAGTAGATGTTCATATTGGAAAATTAAGAGACAAAATTGAAG
ATGATCCTAAAAATCCAGAGATGATTAAAACAATCAGGGGCTATGGCTATCAGTTTAAGGAGATGAAGGATGCTACAAAA
TCTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GIX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

51.293

96.266

0.494
  micA Streptococcus pneumoniae Cp1015

48.918

95.851

0.469
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.194

98.34

0.415
  covR Streptococcus salivarius strain HSISS4

39.316

97.095

0.382

Multiple sequence alignment