Detailed information NTG1016659

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: ABG809_RS06020
• Genome accession: NZ_CP159893
• Coordinates: 1224361..1225035 (+)
• Length: 224 a.a.
• NCBI ID: WP_003099507.1
• Uniprot ID: -
• Organism: Streptococcus iniae strain QMA0177
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1219361..1230035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABG809_RS06000 (ABG809_06000)	pstB	1219361..1220164 (+)	804	WP_003099499.1	phosphate ABC transporter ATP-binding protein PstB	-
ABG809_RS06005 (ABG809_06005)	pstB	1220176..1220934 (+)	759	WP_003099501.1	phosphate ABC transporter ATP-binding protein PstB	-
ABG809_RS06010 (ABG809_06010)	phoU	1220989..1221642 (+)	654	WP_003099503.1	phosphate signaling complex protein PhoU	-
ABG809_RS06015 (ABG809_06015)	-	1221704..1224240 (+)	2537	Protein_1135	M1 family metallopeptidase	-
ABG809_RS06020 (ABG809_06020)	ciaR	1224361..1225035 (+)	675	WP_003099507.1	response regulator transcription factor	Regulator
ABG809_RS06025 (ABG809_06025)	ciaH	1225028..1226338 (+)	1311	WP_003099509.1	cell wall metabolism sensor histidine kinase WalK	Regulator
ABG809_RS06030 (ABG809_06030)	rpsT	1226510..1226752 (-)	243	WP_220701811.1	30S ribosomal protein S20	-
ABG809_RS06035 (ABG809_06035)	coaA	1226812..1227732 (-)	921	WP_003099512.1	type I pantothenate kinase	-
ABG809_RS06040 (ABG809_06040)	-	1227991..1228588 (+)	598	Protein_1140	class I SAM-dependent methyltransferase	-
ABG809_RS06045 (ABG809_06045)	-	1228575..1229851 (+)	1277	Protein_1141	pyrimidine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25562.41 Da
• Isoelectric Point: 4.3757

>NTDB_id=1016659 ABG809_RS06020 WP_003099507.1 1224361..1225035(+) (ciaR) [Streptococcus iniae strain QMA0177]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGFYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KESLDDKGHGFDLGADDYLTKPFYLEELKMRIQALLKRTGKMTTSQLSYGNISIDTERNMVKVGDTTIELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVDNLQTLRSVGYILKTNG

Nucleotide

• Length: 675 bp

>NTDB_id=1016659 ABG809_RS06020 WP_003099507.1 1224361..1225035(+) (ciaR) [Streptococcus iniae strain QMA0177]
ATGATAAAAATATTACTTGTTGAAGATGATTTAAGTTTATCTAATTCGATTTTTGATTTTTTAGATGATTTTGCTGATGT
TATGCAGGTTTTTGATGGAGATGAAGGTTTTTATGAGGCTGAAAGTGGTGTTTATGATCTTATTCTCCTGGACTTAATGT
TACCTGAAAAAAATGGTTTTCAAGTCCTAAAAGAATTAAGAGAAAAAGACATCAAAACGCCTGTTCTTATTATGACTGCT
AAAGAAAGTCTTGACGATAAAGGGCATGGCTTTGACCTTGGAGCTGATGACTACCTAACCAAACCATTTTATTTAGAGGA
GCTAAAAATGCGTATTCAAGCCCTCTTGAAACGAACTGGTAAGATGACTACCAGTCAGCTATCTTATGGGAATATCAGTA
TTGATACTGAACGAAATATGGTAAAAGTCGGAGACACTACCATTGAGCTTCTTGGAAAAGAGTATGATTTACTCATTTAT
CTCCTTCAAAATCAAAATGTTATTTTACCTAAATCACAGATTTTTGACCGTATATGGGGATTCGACAGTGATACCACAAT
ATCAGTTGTAGAGGTTTATGTTTCAAAAATCAGAAAAAAACTAAAAGGGACAGATTTTGTAGACAACCTTCAAACGCTTA
GAAGTGTCGGATACATCTTAAAAACAAATGGCTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae D39	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae R6	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae TIGR4	84.615	98.661	0.835
ciaR	Streptococcus mutans UA159	84.163	98.661	0.83
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.767	100	0.393
covR	Streptococcus salivarius strain HSISS4	36.726	100	0.371