Detailed information NTG1011384

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ABR328_RS08995
• Genome accession: NZ_CP158462
• Coordinates: 1679578..1681770 (+)
• Length: 730 a.a.
• NCBI ID: WP_016372265.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei strain TCI727
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1674578..1686770

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABR328_RS08960 (ABR328_08960)	-	1674673..1674846 (+)	174	WP_016365869.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
ABR328_RS08965 (ABR328_08965)	-	1674885..1675058 (+)	174	WP_003599800.1	bacteriocin	-
ABR328_RS08970 (ABR328_08970)	-	1675332..1675571 (-)	240	WP_016372262.1	hypothetical protein	-
ABR328_RS08975 (ABR328_08975)	-	1676118..1676315 (+)	198	WP_003661762.1	hypothetical protein	-
ABR328_RS08980 (ABR328_08980)	-	1676677..1677483 (-)	807	WP_016372263.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
ABR328_RS08985 (ABR328_08985)	-	1677488..1678606 (-)	1119	WP_016372264.1	GHKL domain-containing protein	-
ABR328_RS08990 (ABR328_08990)	-	1678975..1679112 (+)	138	WP_003571414.1	hypothetical protein	-
ABR328_RS08995 (ABR328_08995)	comA	1679578..1681770 (+)	2193	WP_016372265.1	peptide cleavage/export ABC transporter	Regulator
ABR328_RS09000 (ABR328_09000)	-	1681781..1683160 (+)	1380	WP_350345693.1	bacteriocin secretion accessory protein	-
ABR328_RS09005 (ABR328_09005)	-	1683334..1683683 (+)	350	Protein_1625	hypothetical protein	-
ABR328_RS09010 (ABR328_09010)	-	1683756..1684067 (+)	312	WP_003580849.1	hypothetical protein	-
ABR328_RS09015 (ABR328_09015)	-	1684373..1685728 (+)	1356	WP_003567335.1	threonine/serine exporter family protein	-
ABR328_RS09020 (ABR328_09020)	-	1685829..1686124 (+)	296	Protein_1628	bacteriocin immunity protein	-
ABR328_RS09025 (ABR328_09025)	-	1686317..1686601 (+)	285	WP_003599758.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81315.60 Da
• Isoelectric Point: 7.2448

>NTDB_id=1011384 ABR328_RS08995 WP_016372265.1 1679578..1681770(+) (comA) [Lacticaseibacillus paracasei strain TCI727]
MIKYNIKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQLRKED
KGSLFAFVPMLARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVNTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=1011384 ABR328_RS08995 WP_016372265.1 1679578..1681770(+) (comA) [Lacticaseibacillus paracasei strain TCI727]
ATGATCAAATACAACATAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAATTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGCTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTCGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCACCAGAACCGCAATATCAACTACGCAAAGAGGAT
AAAGGCAGTCTTTTTGCGTTTGTGCCGATGCTGGCGCGGCAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGCCTCATCCTCGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCTATTATCGAAGACTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCTGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGAACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCCATC
AGTGATGTTGATCTAACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCTGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCTG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGGAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTAACCATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGATCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (510-662)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.635	98.356	0.577
comA	Streptococcus pneumoniae Rx1	58.078	98.356	0.571
comA	Streptococcus pneumoniae D39	58.078	98.356	0.571
comA	Streptococcus pneumoniae R6	58.078	98.356	0.571
comA	Streptococcus mitis SK321	57.939	98.356	0.57
comA	Streptococcus pneumoniae TIGR4	57.66	98.356	0.567
comA	Streptococcus gordonii str. Challis substr. CH1	57.103	98.356	0.562
comA/nlmT	Streptococcus mutans UA159	54.986	98.904	0.544