Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   H1W90_RS08090 Genome accession   NZ_LR822033
Coordinates   1565996..1567363 (-) Length   455 a.a.
NCBI ID   WP_084829837.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1048     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1560996..1572363
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W90_RS08065 (STHERMO_1798) - 1561400..1561654 (-) 255 WP_054571825.1 Blp family class II bacteriocin -
  H1W90_RS10450 (STHERMO_1799) - 1561905..1562306 (-) 402 WP_011226490.1 hypothetical protein -
  H1W90_RS08070 (STHERMO_1802) - 1563274..1563480 (-) 207 WP_084829836.1 bacteriocin class II family protein -
  H1W90_RS08075 (STHERMO_1803) comE/blpR 1563731..1564462 (+) 732 WP_180481100.1 LytR/AlgR family response regulator transcription factor Regulator
  H1W90_RS10150 comD/blpH 1564999..1565802 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  H1W90_RS08085 (STHERMO_1805) - 1565820..1565981 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1W90_RS08090 (STHERMO_1806) comB 1565996..1567363 (-) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator
  H1W90_RS08095 (STHERMO_1807) comA/nlmT 1567379..1569532 (-) 2154 WP_180481101.1 peptide cleavage/export ABC transporter Regulator
  H1W90_RS08100 (STHERMO_1812) - 1570546..1572291 (-) 1746 WP_180481102.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50399.10 Da        Isoelectric Point: 4.7492

>NTDB_id=1010963 H1W90_RS08090 WP_084829837.1 1565996..1567363(-) (comB) [Streptococcus thermophilus isolate STH_CIRM_1048]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLESRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1010963 H1W90_RS08090 WP_084829837.1 1565996..1567363(-) (comB) [Streptococcus thermophilus isolate STH_CIRM_1048]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAAGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.246

99.121

0.389
  comB Streptococcus pneumoniae D39

39.246

99.121

0.389
  comB Streptococcus pneumoniae R6

39.246

99.121

0.389
  comB Streptococcus pneumoniae TIGR4

38.581

99.121

0.382
  comB Streptococcus mitis SK321

37.916

99.121

0.376
  comB Streptococcus mitis NCTC 12261

37.916

99.121

0.376

Multiple sequence alignment