Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   H1W90_RS10150 Genome accession   NZ_LR822033
Coordinates   1564999..1565802 (+) Length   267 a.a.
NCBI ID   WP_224103634.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1048     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1559999..1570802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W90_RS08065 (STHERMO_1798) - 1561400..1561654 (-) 255 WP_054571825.1 Blp family class II bacteriocin -
  H1W90_RS10450 (STHERMO_1799) - 1561905..1562306 (-) 402 WP_011226490.1 hypothetical protein -
  H1W90_RS08070 (STHERMO_1802) - 1563274..1563480 (-) 207 WP_084829836.1 bacteriocin class II family protein -
  H1W90_RS08075 (STHERMO_1803) comE/blpR 1563731..1564462 (+) 732 WP_180481100.1 LytR/AlgR family response regulator transcription factor Regulator
  H1W90_RS10150 comD/blpH 1564999..1565802 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  H1W90_RS08085 (STHERMO_1805) - 1565820..1565981 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1W90_RS08090 (STHERMO_1806) comB 1565996..1567363 (-) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator
  H1W90_RS08095 (STHERMO_1807) comA/nlmT 1567379..1569532 (-) 2154 WP_180481101.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30835.17 Da        Isoelectric Point: 4.8309

>NTDB_id=1010991 H1W90_RS10150 WP_224103634.1 1564999..1565802(+) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_1048]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=1010991 H1W90_RS10150 WP_224103634.1 1564999..1565802(+) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_1048]
ATGTATCTTGAAAACACTACTCACTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGAAAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAGAAAAATCTCCAGCTAG
AGAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGTCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAATACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGATTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCATAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363