Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ABPD34_RS02690 Genome accession   NZ_CP158359
Coordinates   538533..539795 (-) Length   420 a.a.
NCBI ID   WP_029237456.1    Uniprot ID   A0A1X4JLK3
Organism   Weissella cibaria strain CXO-1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 533533..544795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABPD34_RS02665 pnuC 533734..534531 (-) 798 WP_010372047.1 nicotinamide riboside transporter PnuC -
  ABPD34_RS02670 rpoE 534737..535330 (-) 594 WP_010372050.1 DNA-directed RNA polymerase subunit delta -
  ABPD34_RS02675 yidA 535411..536247 (-) 837 WP_010372054.1 sugar-phosphatase -
  ABPD34_RS02680 - 536293..537651 (-) 1359 WP_010372056.1 HD domain-containing protein -
  ABPD34_RS02685 - 537757..538194 (+) 438 WP_010372059.1 DUF1934 domain-containing protein -
  ABPD34_RS02690 htrA 538533..539795 (-) 1263 WP_029237456.1 trypsin-like peptidase domain-containing protein Regulator
  ABPD34_RS02695 - 539910..540710 (-) 801 WP_010372065.1 MBL fold metallo-hydrolase -
  ABPD34_RS02700 yycI 540812..541624 (-) 813 WP_010372067.1 two-component system regulatory protein YycI -
  ABPD34_RS02705 yycH 541624..542949 (-) 1326 WP_010372070.1 two-component system activity regulator YycH -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 42751.56 Da        Isoelectric Point: 4.9746

>NTDB_id=1010899 ABPD34_RS02690 WP_029237456.1 538533..539795(-) (htrA) [Weissella cibaria strain CXO-1]
MKKTSTTKIAIIGIVAGLVGGGAAAGGVTYLNNAGTFSTVTTGKTTPVKVSNSNVKGESDATKAFNKVSGAVVSVINLQK
QQSLSDSGSLFGGLFGGDESSSSDSKSTDSSDLQTASEGSGVVYKKDGNTAYIVTNNHVVSGSNALQVLLSDGTKLTATL
VGTDEQTDLAVLKINASKVSEVADFANSSKIEPGQSVLAIGSPLGSEYATSVTEGIISATKREVDATNENGDSLGKATVI
QTDAAINPGNSGGPLVNLAGQVVGINSMKLASSTDGTSVEGMGFAIPANTVVNIINELEKNGKVERPALGVSMVDLSNVS
TTDQSTILKLPTSVSGGVVVISTEDGSAAATAGLKKYDVITKIDDTEVTGSGDLRDALYKHKVGDTIKVTYYRDGKQKTT
DVKLTKTTSSLSTKSEANQN

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=1010899 ABPD34_RS02690 WP_029237456.1 538533..539795(-) (htrA) [Weissella cibaria strain CXO-1]
ATGAAAAAGACATCAACCACAAAAATAGCAATTATCGGGATTGTTGCCGGGCTAGTCGGCGGTGGTGCCGCTGCTGGTGG
CGTAACTTACCTGAATAATGCCGGCACTTTTTCAACAGTTACGACTGGTAAGACGACACCGGTGAAGGTAAGTAACTCGA
ACGTGAAGGGCGAATCTGATGCAACGAAGGCCTTTAACAAGGTGTCGGGCGCAGTTGTGTCAGTGATTAACTTGCAAAAG
CAACAATCACTTTCAGACAGCGGCTCATTATTTGGTGGGTTGTTTGGTGGTGATGAGTCATCGTCAAGTGATAGCAAGTC
AACAGATTCATCAGACCTTCAAACGGCTTCTGAGGGATCAGGAGTGGTTTACAAGAAGGATGGTAACACGGCTTATATCG
TCACGAACAACCACGTGGTTTCAGGGTCAAACGCGTTGCAAGTCTTGTTGAGCGATGGGACTAAGCTGACGGCGACGTTG
GTTGGTACTGATGAGCAAACTGATTTGGCTGTGTTGAAGATTAATGCAAGCAAGGTATCAGAGGTAGCTGACTTTGCTAA
CTCAAGTAAGATTGAGCCGGGACAATCAGTTTTGGCCATCGGGTCACCATTGGGATCAGAGTATGCGACGTCAGTGACAG
AAGGAATCATTTCAGCAACGAAGCGTGAAGTCGATGCCACAAATGAGAATGGTGATTCACTCGGTAAGGCCACGGTTATC
CAAACGGACGCGGCAATTAATCCCGGAAATTCAGGTGGCCCATTGGTAAACTTGGCCGGTCAAGTCGTTGGTATCAACTC
AATGAAGTTGGCATCGTCAACTGACGGTACGTCGGTTGAAGGAATGGGATTTGCGATTCCGGCTAATACGGTAGTCAACA
TCATTAACGAGTTGGAGAAGAATGGAAAGGTTGAACGACCAGCTTTGGGCGTTTCAATGGTTGATTTGAGTAACGTCTCA
ACGACGGATCAATCAACAATCTTGAAGTTGCCAACCAGCGTTTCAGGTGGTGTCGTGGTCATCAGTACTGAAGATGGTTC
AGCAGCAGCGACTGCGGGCTTGAAGAAGTACGATGTGATTACCAAGATTGACGATACTGAGGTTACTGGTTCTGGTGACT
TGCGAGATGCTTTGTATAAGCACAAGGTTGGTGACACGATTAAGGTAACTTACTACCGCGATGGTAAGCAAAAGACGACT
GACGTGAAATTGACGAAGACGACGAGCTCATTATCAACGAAGTCAGAAGCAAATCAAAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(194-409)

PDZ domain (PDZ_2)

(307-404)

Trypsin-like peptidase domain (Trypsin_2)

(119-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X4JLK3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

49.637

98.333

0.488
  htrA Streptococcus mutans UA159

50.646

92.143

0.467
  htrA Streptococcus mitis NCTC 12261

48.13

95.476

0.46
  htrA Streptococcus pneumoniae TIGR4

51.676

85.238

0.44
  htrA Streptococcus pneumoniae D39

51.676

85.238

0.44
  htrA Streptococcus pneumoniae Rx1

51.676

85.238

0.44
  htrA Streptococcus pneumoniae R6

51.676

85.238

0.44

Multiple sequence alignment