Detailed information NTG1009908

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: Q6165_RS13585
• Genome accession: NZ_CP158131
• Coordinates: 2714821..2715708 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN51
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2709821..2720708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q6165_RS13555 (Q6165_13545)	-	2709840..2709932 (+)	93	WP_010956583.1	hypothetical protein	-
Q6165_RS13560 (Q6165_13550)	-	2710040..2710537 (-)	498	WP_001065268.1	glutathione peroxidase	-
Q6165_RS13565 (Q6165_13555)	-	2710547..2710807 (-)	261	WP_001791974.1	hypothetical protein	-
Q6165_RS13570 (Q6165_13560)	-	2711189..2711302 (-)	114	Protein_2634	hypothetical protein	-
Q6165_RS13575 (Q6165_13565)	-	2711961..2713961 (-)	2001	WP_000776750.1	ABC transporter permease	-
Q6165_RS13580 (Q6165_13570)	-	2713958..2714713 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
Q6165_RS13585 (Q6165_13575)	braS	2714821..2715708 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
Q6165_RS13590 (Q6165_13580)	braR	2715719..2716384 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
Q6165_RS13595 (Q6165_13585)	-	2716410..2716610 (-)	201	WP_000604730.1	hypothetical protein	-
Q6165_RS13600 (Q6165_13590)	-	2716808..2718232 (+)	1425	WP_000953755.1	alkaline phosphatase	-
Q6165_RS13605 (Q6165_13595)	-	2718292..2718393 (-)	102	WP_000731976.1	SE2200 family small protein	-
Q6165_RS13610 (Q6165_13600)	-	2718515..2718970 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
Q6165_RS13615 (Q6165_13605)	-	2719215..2719976 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1009908 Q6165_RS13585 WP_000143425.1 2714821..2715708(-) (braS) [Staphylococcus aureus strain BSN51]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1009908 Q6165_RS13585 WP_000143425.1 2714821..2715708(-) (braS) [Staphylococcus aureus strain BSN51]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1