Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ABKA15_RS07245 Genome accession   NZ_CP157941
Coordinates   1476832..1478133 (-) Length   433 a.a.
NCBI ID   WP_106387857.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_010     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1471832..1483133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA15_RS07215 (ABKA15_07210) - 1472587..1473150 (-) 564 WP_049512409.1 YutD-like domain-containing protein -
  ABKA15_RS07220 (ABKA15_07215) sepM 1473290..1474345 (-) 1056 WP_049512407.1 SepM family pheromone-processing serine protease Regulator
  ABKA15_RS07225 (ABKA15_07220) coaD 1474326..1474823 (-) 498 WP_049512405.1 pantetheine-phosphate adenylyltransferase -
  ABKA15_RS07230 (ABKA15_07225) rsmD 1474813..1475361 (-) 549 WP_185952239.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ABKA15_RS07235 (ABKA15_07230) raiA 1475550..1476092 (-) 543 WP_106387855.1 ribosome-associated translation inhibitor RaiA -
  ABKA15_RS07240 (ABKA15_07235) comFC/cflB 1476170..1476835 (-) 666 WP_106387856.1 ComF family protein Machinery gene
  ABKA15_RS07245 (ABKA15_07240) comFA/cflA 1476832..1478133 (-) 1302 WP_106387857.1 DEAD/DEAH box helicase Machinery gene
  ABKA15_RS07250 (ABKA15_07245) - 1478190..1478825 (+) 636 WP_106387858.1 YigZ family protein -
  ABKA15_RS07255 (ABKA15_07250) cysK 1478924..1479853 (+) 930 WP_106387859.1 cysteine synthase A -
  ABKA15_RS07260 (ABKA15_07255) - 1480444..1481295 (-) 852 WP_059221073.1 DNA adenine methylase -
  ABKA15_RS07265 (ABKA15_07260) - 1481288..1483105 (-) 1818 WP_106079176.1 hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 48962.91 Da        Isoelectric Point: 8.6871

>NTDB_id=1009131 ABKA15_RS07245 WP_106387857.1 1476832..1478133(-) (comFA/cflA) [Streptococcus sp. KHUD_010]
MTELQDCLGRIFTKSQLSPELQLQAQTVAGMVEEKGKISCNRCGQVIDKEKHQLPIGAYYCRFCLILGRVRSDEDLYYFP
QEEFPKANVLKWQGKLTVFQAKVSQGLVEAVAKRKNSLVHAVTGAGKTEMIYQVVAQVINQGGAVCLASPRIDVCLELYR
RLKVDFTCDISLLHGESEAYSRSPLVIATTHQLLKFYQTFDLLIVDEVDAFPYVDNPMLYHAVHQAVKVEGTKIFLTATS
TDELDKKVAKGELTRLSLPRRFHGNPLIVPQKIWLADFQKYLGQKKLVPKLRQFIQKQRKTSFPLLIFASEIKKGQEFAE
ILQSTFPNEKVGFVASTTENRLEIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSMD
RPTGELIFFHDGATMAIEKAIKEIQEMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1009131 ABKA15_RS07245 WP_106387857.1 1476832..1478133(-) (comFA/cflA) [Streptococcus sp. KHUD_010]
ATGACGGAATTACAAGATTGTTTAGGTCGTATTTTTACCAAAAGTCAACTGTCACCAGAATTGCAATTGCAAGCACAAAC
CGTAGCTGGAATGGTAGAAGAAAAAGGGAAAATAAGTTGCAATCGCTGTGGACAAGTCATTGACAAAGAAAAACACCAAT
TGCCAATAGGTGCTTATTATTGTAGGTTTTGCTTGATCTTAGGAAGGGTCAGAAGTGATGAAGATCTTTACTATTTTCCA
CAGGAAGAATTTCCTAAAGCGAATGTCTTGAAATGGCAAGGGAAGTTGACAGTATTCCAAGCCAAGGTTTCTCAAGGACT
TGTAGAGGCGGTTGCTAAACGAAAAAATAGCTTGGTTCACGCAGTCACGGGAGCCGGAAAGACGGAAATGATTTATCAAG
TAGTAGCACAAGTCATCAATCAAGGTGGTGCCGTCTGCTTGGCTAGCCCCAGAATTGATGTCTGCTTAGAACTTTATCGC
AGACTGAAAGTAGATTTTACCTGTGATATTTCACTCCTGCACGGTGAATCAGAAGCATACTCCCGCAGTCCTCTCGTGAT
TGCTACAACGCATCAGCTTCTTAAATTTTATCAAACCTTTGATCTTCTTATCGTTGATGAAGTAGATGCCTTTCCTTATG
TGGACAATCCGATGCTTTATCATGCGGTTCATCAGGCAGTTAAAGTAGAGGGAACGAAGATTTTCTTAACAGCAACTTCC
ACAGATGAGTTGGACAAAAAAGTGGCTAAAGGAGAATTAACTCGTTTGAGTCTTCCTAGACGTTTTCATGGGAATCCTTT
GATTGTTCCTCAAAAAATTTGGTTGGCAGATTTTCAAAAATATCTTGGTCAAAAGAAGCTAGTTCCTAAGTTAAGACAGT
TTATTCAAAAGCAGAGAAAAACAAGCTTTCCACTTCTTATTTTTGCTTCTGAGATTAAAAAGGGGCAGGAATTTGCAGAG
ATTCTTCAAAGCACTTTTCCTAATGAAAAAGTTGGCTTTGTAGCCTCGACGACTGAAAATCGACTGGAAATTGTAGAGAA
ATTTCGTCAAAAAGAAATCACGATTTTGGTAACGACGACGATTTTGGAGCGTGGGGTGACTTTTCCTTGCGTGGATGTTT
TCGTGGTAGAAGCCAACCACCGTCTGTTTAGTCGCAGCGCTCTGGTACAAATCGCTGGACGCGTCGGTCGCAGTATGGAT
CGACCGACAGGCGAGTTAATCTTTTTTCATGACGGTGCGACTATGGCGATAGAAAAAGCGATTAAAGAAATTCAGGAGAT
GAATCAGGAGGCTGGTTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(108-245)

Helicase conserved C-terminal domain (Helicase_C)

(291-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae D39

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae R6

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae TIGR4

71.262

98.845

0.704
  comFA/cflA Streptococcus mitis NCTC 12261

71.127

98.383

0.7
  comFA/cflA Streptococcus mitis SK321

70.423

98.383

0.693
  comFA Lactococcus lactis subsp. cremoris KW2

55.276

91.917

0.508
  comFA Latilactobacillus sakei subsp. sakei 23K

39.679

100

0.4
  comFA Bacillus subtilis subsp. subtilis str. 168

39.259

93.533

0.367

Multiple sequence alignment