Detailed information NTG1009129

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ABKA15_RS07220
• Genome accession: NZ_CP157941
• Coordinates: 1473290..1474345 (-)
• Length: 351 a.a.
• NCBI ID: WP_049512407.1
• Uniprot ID: A0A7L8W760
• Organism: Streptococcus sp. KHUD_010
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1468290..1479345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKA15_RS07195 (ABKA15_07190)	cclA/cilC	1468543..1469202 (+)	660	WP_186832755.1	A24 family peptidase	Machinery gene
ABKA15_RS07200 (ABKA15_07195)	trpB	1469362..1470558 (-)	1197	WP_264341044.1	tryptophan synthase subunit beta	-
ABKA15_RS07205 (ABKA15_07200)	-	1470943..1471473 (-)	531	WP_186832757.1	VanZ family protein	-
ABKA15_RS07210 (ABKA15_07205)	rlmN	1471466..1472548 (-)	1083	WP_350015333.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ABKA15_RS07215 (ABKA15_07210)	-	1472587..1473150 (-)	564	WP_049512409.1	YutD-like domain-containing protein	-
ABKA15_RS07220 (ABKA15_07215)	sepM	1473290..1474345 (-)	1056	WP_049512407.1	SepM family pheromone-processing serine protease	Regulator
ABKA15_RS07225 (ABKA15_07220)	coaD	1474326..1474823 (-)	498	WP_049512405.1	pantetheine-phosphate adenylyltransferase	-
ABKA15_RS07230 (ABKA15_07225)	rsmD	1474813..1475361 (-)	549	WP_185952239.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ABKA15_RS07235 (ABKA15_07230)	raiA	1475550..1476092 (-)	543	WP_106387855.1	ribosome-associated translation inhibitor RaiA	-
ABKA15_RS07240 (ABKA15_07235)	comFC/cflB	1476170..1476835 (-)	666	WP_106387856.1	ComF family protein	Machinery gene
ABKA15_RS07245 (ABKA15_07240)	comFA/cflA	1476832..1478133 (-)	1302	WP_106387857.1	DEAD/DEAH box helicase	Machinery gene
ABKA15_RS07250 (ABKA15_07245)	-	1478190..1478825 (+)	636	WP_106387858.1	YigZ family protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38352.19 Da
• Isoelectric Point: 10.0691

>NTDB_id=1009129 ABKA15_RS07220 WP_049512407.1 1473290..1474345(-) (sepM) [Streptococcus sp. KHUD_010]
MEKPRNKFKKWPIIAIAGLILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEAKKANPKAKTNYETAL
EAAKKIKTNMKIVPVKTLQDAIDYLKDTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=1009129 ABKA15_RS07220 WP_049512407.1 1473290..1474345(-) (sepM) [Streptococcus sp. KHUD_010]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAATAGCAGGGCTGATTTTGCTTTTCTTATCTTTTGT
GGTTCCCTTGCCTTATTATATTGAGGTGCCGGGTGGTGCAGCAGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTACAACTTTGTAACGGTTGGAATTCAGCATGCGACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACACCTTTTACAGATATTTATTCGGCGAAGGATTTGACTGGCGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACATCGCAAAACCTAGCTAAATACCAAGGATTGAAAAAAGCTGGCAAAGATATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGCATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GACAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTTGGAGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAATCTGCTACAGGTAAAATCATCAAACTTGAAAATGGGAAAAACGGGATTGGTATTAGCT
TGATCGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACAGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGTAGAAATATTGCTGGGACAGGCTCAAT
TGACCGCGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCAAAAAATGGTGCAGAAATTT
TCTTTGCACCAAATAATCCAGTTACTAAGGAAGCTAAAAAAGCTAATCCTAAAGCGAAAACTAACTATGAGACCGCTTTG
GAAGCTGCTAAAAAAATTAAGACCAATATGAAAATTGTACCCGTGAAAACTTTACAAGATGCCATTGATTACCTCAAGGA
CACAAAGAAGTCGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (133-197)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-300)

3D structure

• AlphaFold DB: A0A7L8W760

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	64.244	98.006	0.63