Detailed information NTG1007474

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: ABKJ27_RS07700
• Genome accession: NZ_CP157578
• Coordinates: 1598056..1598793 (-)
• Length: 245 a.a.
• NCBI ID: WP_410011634.1
• Uniprot ID: -
• Organism: Streptococcus sp. KHUD_011
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1593056..1603793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKJ27_RS07660 (ABKJ27_07675)	-	1593164..1593853 (-)	690	WP_410011629.1	CPBP family intramembrane glutamic endopeptidase	-
ABKJ27_RS07665 (ABKJ27_07680)	-	1593882..1594202 (-)	321	WP_000645118.1	hypothetical protein	-
ABKJ27_RS07670 (ABKJ27_07685)	-	1594217..1594444 (-)	228	WP_410011630.1	ComC/BlpC family peptide pheromone/bacteriocin	-
ABKJ27_RS07675 (ABKJ27_07690)	-	1594465..1594650 (-)	186	WP_410012148.1	hypothetical protein	-
ABKJ27_RS07680 (ABKJ27_07695)	-	1595012..1595416 (-)	405	WP_410011631.1	immunity protein	-
ABKJ27_RS07685 (ABKJ27_07700)	-	1595869..1595988 (-)	120	WP_410011632.1	PncF family bacteriocin immunity protein	-
ABKJ27_RS07690	-	1596268..1596459 (-)	192	WP_247932365.1	hypothetical protein	-
ABKJ27_RS07695 (ABKJ27_07710)	-	1596693..1598042 (-)	1350	WP_410011633.1	sensor histidine kinase	-
ABKJ27_RS07700 (ABKJ27_07715)	comE/blpR	1598056..1598793 (-)	738	WP_410011634.1	response regulator transcription factor	Regulator
ABKJ27_RS07705 (ABKJ27_07720)	-	1599089..1599418 (+)	330	WP_084947397.1	helicase BlpT	-
ABKJ27_RS07710 (ABKJ27_07725)	-	1599480..1600529 (-)	1050	WP_410011635.1	ABC transporter permease	-
ABKJ27_RS07715 (ABKJ27_07730)	pptA	1600526..1601257 (-)	732	WP_000889954.1	ABC transporter ATP-binding protein	Regulator
ABKJ27_RS07720 (ABKJ27_07735)	-	1601325..1601735 (+)	411	WP_410011636.1	HIT family protein	-
ABKJ27_RS07725 (ABKJ27_07740)	-	1601745..1602032 (+)	288	WP_410011637.1	hypothetical protein	-
ABKJ27_RS07730 (ABKJ27_07745)	dnaJ	1602321..1603457 (-)	1137	WP_001066308.1	molecular chaperone DnaJ	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28726.90 Da
• Isoelectric Point: 6.3923

>NTDB_id=1007474 ABKJ27_RS07700 WP_410011634.1 1598056..1598793(-) (comE/blpR) [Streptococcus sp. KHUD_011]
MRIFVLEDDFSQQTRIEATIEKLLKEHQITPSSFAVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVRLDKKEKLLFFPNGGSCMIARYKVREVSEA
INNLH

Nucleotide

• Length: 738 bp

>NTDB_id=1007474 ABKJ27_RS07700 WP_410011634.1 1598056..1598793(-) (comE/blpR) [Streptococcus sp. KHUD_011]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAGCAGACTAGGATTGAAGCGACGATTGAGAAACTCTTGAAGGAACA
TCAGATCACTCCCAGTTCTTTTGCGGTCTTTGGTAAGCCAGATCAACTGCTGGCAGAGGTGCATGAGAAGGGAGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGGCTAGAAGTGGCTAGAAAGATTCGGGATCGAGAT
CCCTATGCCCTGATTGTCTTTGTGACAACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGGCCTTGTCGGCAGAGGAGTTTGAATCTCGTATCGAAACAGCCCTTCTCTATGCCAATAGTCAAGACA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAGTATCCTTTTAAAGAGGTTTATTAT
CTTGAAACATCGCCCAGAGCTCATCGTGTTATTCTCTATACCAAGACAGACAGACTGGAATTTACAGCCAGTTTAGAGGA
GGTTTTCAAGCAGGAACCCCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATTAATCCTGCCAATGTAGTTCGTTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCTAATGGCGGAAGCTGTATGATTGCGCGTTATAAGGTCAGAGAAGTGTCTGAAGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-241)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.321	99.184	0.539
comE/comE1	Streptococcus equinus JB1	42.616	96.735	0.412
comE/comE2	Streptococcus equinus JB1	39.256	98.776	0.388
comE	Streptococcus infantis strain Atu-4	36.179	100	0.363