Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ABKJ27_RS06040 Genome accession   NZ_CP157578
Coordinates   1300634..1301371 (-) Length   245 a.a.
NCBI ID   WP_410011516.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1295634..1306371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS06025 (ABKJ27_06040) msrB 1297289..1298227 (-) 939 WP_410011513.1 peptide-methionine (R)-S-oxide reductase MsrB -
  ABKJ27_RS06030 (ABKJ27_06045) thrB 1298325..1299194 (-) 870 WP_410011514.1 homoserine kinase -
  ABKJ27_RS06035 (ABKJ27_06050) - 1299196..1300482 (-) 1287 WP_410011515.1 homoserine dehydrogenase -
  ABKJ27_RS06040 (ABKJ27_06055) mecA 1300634..1301371 (-) 738 WP_410011516.1 adaptor protein MecA Regulator
  ABKJ27_RS06045 (ABKJ27_06060) - 1301562..1302596 (-) 1035 WP_410011517.1 prephenate dehydratase -
  ABKJ27_RS06050 (ABKJ27_06065) - 1302589..1304058 (-) 1470 WP_410011518.1 O-antigen polysaccharide polymerase Wzy family protein -
  ABKJ27_RS06055 (ABKJ27_06070) - 1304074..1305060 (-) 987 WP_410011519.1 glycosyltransferase family 2 protein -
  ABKJ27_RS06060 (ABKJ27_06075) - 1305062..1306165 (-) 1104 WP_410011520.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28480.32 Da        Isoelectric Point: 4.0236

>NTDB_id=1007468 ABKJ27_RS06040 WP_410011516.1 1300634..1301371(-) (mecA) [Streptococcus sp. KHUD_011]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPESFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEVESKKEPYIYYILSFT
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1007468 ABKJ27_RS06040 WP_410011516.1 1300634..1301371(-) (mecA) [Streptococcus sp. KHUD_011]
ATGAAAATGAAACAAATTAGTGATACAACTTTGAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGCATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTAGATGAGTTAGAGATGCCTGAAAGCT
TTTTGGATACAGGTATGTTGAGCTTCCGTGTGACTCCAAAACCGGATAAGGTCGATGTTTTTGTAACTAAATCAAAGATT
GACCAAAATCTAGATTTTGAAGATTTATCGGATTTACCAGATATGGAAGAATTGGCTCAAATGTCGCCAGATGAATTTAT
CAAAACCTTGGAAAAAAGCATCGCAGATAAAACCAAGGATGATATCGAAGCGATTCAATCTCTAGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAGGAGCAGGCTGAACAAGAAGTTGAAAGCAAGAAAGAGCCGTACATCTATTACATCCTTTCTTTTACA
AAATTGGCTGACTTGGTGGCTTTTGCCAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAATGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGTTGTTGGCTCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGCTCAGTCTTGCAGGAGTATGGTCAAGTCTTGATGAATCACGACGCAGTGCTCAAT
CTGCAAAAGATTGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

97.959

100

0.98
  mecA Streptococcus pneumoniae D39

97.959

100

0.98
  mecA Streptococcus pneumoniae R6

97.959

100

0.98
  mecA Streptococcus pneumoniae TIGR4

97.551

100

0.976
  mecA Streptococcus mutans UA159

48.571

100

0.486
  mecA Streptococcus thermophilus LMD-9

46.586

100

0.473
  mecA Streptococcus thermophilus LMG 18311

46.185

100

0.469

Multiple sequence alignment