Detailed information
Bioinformatically predicted
Overview
| Name | comA/nlmT | Type | Regulator |
| Locus tag | ABKJ27_RS04750 | Genome accession | NZ_CP157578 |
| Coordinates | 1025622..1027775 (-) | Length | 717 a.a. |
| NCBI ID | WP_247933197.1 | Uniprot ID | - |
| Organism | Streptococcus sp. KHUD_011 | ||
| Function | transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1015370..1059501 | 1025622..1027775 | within | 0 |
Gene organization within MGE regions
Location: 1015370..1059501
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABKJ27_RS04680 (ABKJ27_04690) | - | 1015370..1016011 (+) | 642 | WP_410011428.1 | peptidylprolyl isomerase | - |
| ABKJ27_RS04685 (ABKJ27_04695) | - | 1016021..1017106 (+) | 1086 | WP_410011429.1 | DNA primase | - |
| ABKJ27_RS04690 (ABKJ27_04700) | - | 1017157..1017390 (+) | 234 | WP_000152419.1 | DUF5965 family protein | - |
| ABKJ27_RS04695 (ABKJ27_04705) | - | 1017387..1017770 (+) | 384 | WP_153224488.1 | DUF5945 family protein | - |
| ABKJ27_RS04700 (ABKJ27_04710) | - | 1017808..1018083 (+) | 276 | WP_410011430.1 | hypothetical protein | - |
| ABKJ27_RS04705 (ABKJ27_04715) | - | 1018628..1018813 (+) | 186 | WP_219137295.1 | bacteriocin class II family protein | - |
| ABKJ27_RS04710 (ABKJ27_04720) | - | 1018828..1018992 (+) | 165 | WP_219137294.1 | Blp family class II bacteriocin | - |
| ABKJ27_RS04715 (ABKJ27_04725) | tnpA | 1019338..1019589 (+) | 252 | Protein_927 | IS200/IS605 family transposase | - |
| ABKJ27_RS04720 (ABKJ27_04730) | - | 1020286..1020684 (-) | 399 | WP_219137293.1 | hypothetical protein | - |
| ABKJ27_RS04725 (ABKJ27_04735) | - | 1020885..1021217 (+) | 333 | WP_219137292.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| ABKJ27_RS04730 (ABKJ27_04740) | - | 1021228..1021968 (+) | 741 | WP_410011431.1 | response regulator transcription factor | - |
| ABKJ27_RS04735 (ABKJ27_04745) | - | 1021979..1023304 (+) | 1326 | WP_219137290.1 | GHKL domain-containing protein | - |
| ABKJ27_RS04740 (ABKJ27_04750) | - | 1023466..1023795 (-) | 330 | Protein_932 | IS5/IS1182 family transposase | - |
| ABKJ27_RS04745 (ABKJ27_04755) | - | 1024252..1025610 (-) | 1359 | WP_247933196.1 | bacteriocin secretion accessory protein | - |
| ABKJ27_RS04750 (ABKJ27_04760) | comA/nlmT | 1025622..1027775 (-) | 2154 | WP_247933197.1 | peptide cleavage/export ABC transporter | Regulator |
| ABKJ27_RS04755 (ABKJ27_04765) | - | 1028081..1028254 (+) | 174 | WP_219137287.1 | Blp family class II bacteriocin | - |
| ABKJ27_RS04760 (ABKJ27_04770) | - | 1028294..1028494 (+) | 201 | WP_219137286.1 | bacteriocin BlpI | - |
| ABKJ27_RS04765 (ABKJ27_04775) | - | 1029611..1030693 (+) | 1083 | WP_410011432.1 | LPXTG cell wall anchor domain-containing protein | - |
| ABKJ27_RS04770 (ABKJ27_04780) | - | 1031104..1032000 (-) | 897 | WP_219137284.1 | tyrosine-type recombinase/integrase | - |
| ABKJ27_RS04775 (ABKJ27_04785) | - | 1032091..1032669 (+) | 579 | WP_049532747.1 | hypothetical protein | - |
| ABKJ27_RS04780 (ABKJ27_04790) | - | 1032670..1033916 (-) | 1247 | Protein_940 | hypothetical protein | - |
| ABKJ27_RS04785 (ABKJ27_04795) | tnpA | 1034387..1034851 (+) | 465 | WP_410011433.1 | IS200/IS605 family transposase | - |
| ABKJ27_RS04790 (ABKJ27_04800) | - | 1035011..1035296 (+) | 286 | Protein_942 | hypothetical protein | - |
| ABKJ27_RS04795 (ABKJ27_04805) | - | 1035350..1037626 (-) | 2277 | WP_410011434.1 | S8 family peptidase | - |
| ABKJ27_RS04800 (ABKJ27_04810) | - | 1037629..1038753 (-) | 1125 | WP_049493780.1 | AAA family ATPase | - |
| ABKJ27_RS04805 (ABKJ27_04815) | - | 1039268..1039627 (+) | 360 | WP_061370830.1 | SAG1252 family conjugative relaxosome accessory protein | - |
| ABKJ27_RS04810 (ABKJ27_04820) | - | 1039637..1040002 (+) | 366 | WP_410011435.1 | MobC family plasmid mobilization relaxosome protein | - |
| ABKJ27_RS04815 (ABKJ27_04825) | - | 1039989..1041851 (+) | 1863 | WP_410011436.1 | SAG1250 family conjugative relaxase | - |
| ABKJ27_RS04820 (ABKJ27_04830) | - | 1041895..1042743 (-) | 849 | WP_025169843.1 | helix-turn-helix domain-containing protein | - |
| ABKJ27_RS04825 (ABKJ27_04840) | - | 1043387..1044244 (+) | 858 | WP_410011437.1 | helix-turn-helix domain-containing protein | - |
| ABKJ27_RS04830 (ABKJ27_04845) | - | 1044527..1045507 (+) | 981 | WP_000114485.1 | radical SAM protein | - |
| ABKJ27_RS04835 (ABKJ27_04850) | - | 1045500..1046057 (+) | 558 | WP_410011438.1 | CYTH domain-containing protein | - |
| ABKJ27_RS04840 (ABKJ27_04855) | - | 1046044..1047267 (+) | 1224 | WP_314414889.1 | hypothetical protein | - |
| ABKJ27_RS04845 (ABKJ27_04860) | - | 1047260..1048453 (+) | 1194 | WP_075228606.1 | ATP-grasp domain-containing protein | - |
| ABKJ27_RS04850 (ABKJ27_04865) | - | 1048473..1049687 (+) | 1215 | WP_410011439.1 | acetyl-CoA carboxylase biotin carboxylase subunit family protein | - |
| ABKJ27_RS04855 (ABKJ27_04870) | - | 1050112..1051323 (+) | 1212 | WP_075228604.1 | MFS transporter | - |
| ABKJ27_RS04860 (ABKJ27_04875) | - | 1052011..1052232 (+) | 222 | WP_000286248.1 | helix-turn-helix domain-containing protein | - |
| ABKJ27_RS04865 (ABKJ27_04880) | - | 1052535..1052768 (+) | 234 | WP_075228603.1 | DNA-binding protein | - |
| ABKJ27_RS04870 (ABKJ27_04885) | - | 1052853..1054361 (+) | 1509 | WP_088777677.1 | tyrosine-type recombinase/integrase | - |
| ABKJ27_RS04875 (ABKJ27_04890) | ylqF | 1054443..1055294 (+) | 852 | WP_000201324.1 | ribosome biogenesis GTPase YlqF | - |
| ABKJ27_RS04880 (ABKJ27_04895) | - | 1055281..1056060 (+) | 780 | WP_410011440.1 | ribonuclease HII | - |
| ABKJ27_RS04885 (ABKJ27_04900) | - | 1056077..1057627 (+) | 1551 | WP_410011441.1 | chloride channel protein | - |
| ABKJ27_RS04890 (ABKJ27_04905) | xerS | 1058431..1059501 (+) | 1071 | WP_020903340.1 | tyrosine recombinase XerS | - |
Sequence
Protein
Download Length: 717 a.a. Molecular weight: 80653.92 Da Isoelectric Point: 8.4367
>NTDB_id=1007458 ABKJ27_RS04750 WP_247933197.1 1025622..1027775(-) (comA/nlmT) [Streptococcus sp. KHUD_011]
MTSYKRTFIPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAKEMNFETRAIQADMSLFETEDL
PYPFIVHVNKEGKLQHYYVVYQNIKKYLIIGDPDPTVKVTKMTKERFASEWTGVAIFLAPSPSYKPHKDKKNGLMSFLPL
IFKQRSLIFYIILASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIIGSVLLVQNTNLFLLSLISVPIYII
IIFAFMKPFEKMNNDVMQSNSMVSSAIIEDINGVETIKSLTSEEIRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNIVILWFGAQIVMTGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFKNTQTLTDSPFL
AGDICFEDISYKYGFGRDTLNNINLSIKQGDKVSIVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKMIDKKVLRQHI
NYLPQQAYIFSGSILENLTLGANQMISQEDIIKACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIENLMAMTDKTIIFVAHRLSISERTNQVIVLNQGKVIETGSHQELMSKQGFYHHLFSK
MTSYKRTFIPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAKEMNFETRAIQADMSLFETEDL
PYPFIVHVNKEGKLQHYYVVYQNIKKYLIIGDPDPTVKVTKMTKERFASEWTGVAIFLAPSPSYKPHKDKKNGLMSFLPL
IFKQRSLIFYIILASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIIGSVLLVQNTNLFLLSLISVPIYII
IIFAFMKPFEKMNNDVMQSNSMVSSAIIEDINGVETIKSLTSEEIRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNIVILWFGAQIVMTGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFKNTQTLTDSPFL
AGDICFEDISYKYGFGRDTLNNINLSIKQGDKVSIVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKMIDKKVLRQHI
NYLPQQAYIFSGSILENLTLGANQMISQEDIIKACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIENLMAMTDKTIIFVAHRLSISERTNQVIVLNQGKVIETGSHQELMSKQGFYHHLFSK
Nucleotide
Download Length: 2154 bp
>NTDB_id=1007458 ABKJ27_RS04750 WP_247933197.1 1025622..1027775(-) (comA/nlmT) [Streptococcus sp. KHUD_011]
ATGACATCTTACAAACGAACCTTTATCCCTCAAATCGACGCTAGGGACTGTGGAGTCGCCGCTTTAGCGTCTATTGCAAA
GTTTTATGGTTCTGACTATTCCTTAGCTCATTTGCGAGAACTAGCTAAAACAAATAAAGAAGGAACGACTGCTCTTGGTA
TCGTCAAAGCAGCCAAAGAAATGAATTTTGAAACAAGAGCTATCCAAGCGGATATGAGCCTCTTTGAAACGGAAGACTTA
CCTTATCCATTTATCGTTCATGTTAATAAAGAGGGCAAACTACAACACTACTACGTTGTCTATCAAAATATAAAAAAATA
TCTTATCATTGGTGATCCTGATCCTACTGTCAAAGTAACAAAAATGACCAAAGAGAGATTTGCTTCCGAATGGACAGGTG
TAGCTATCTTTCTGGCTCCATCTCCCAGCTATAAACCTCATAAGGATAAAAAAAATGGTTTGATGAGCTTTCTCCCCTTA
ATTTTCAAGCAACGCTCACTTATTTTTTATATCATTTTAGCTAGTCTCTTGGTGACTCTTATCAATATTGGTGGCTCATA
CTATCTTCAAGGAATTTTAGATGAATATATTCCTAATCAGATGAAATCAACTCTTGGCATTATCTCCATTGGACTGATTA
TCACCTATATACTTCAACAGATGATGAGTTTCTCACGAGATTACCTCTTGACCGTACTTAGTCAGCGATTAAGTATTGAT
GTGATTCTCTCCTATATTCGCCACATCTTTGAACTTCCTATGTCCTTCTTTGCGACACGGCGAACCGGTGAGGTCATCTC
TCGTTTTACAGATGCCAATTCAATCATTGACGCTCTCGCTTCGACGATTTTGTCACTCTTCCTTGATGTCTCTATATTGT
TCATTATTGGTAGTGTACTTTTGGTACAAAACACCAACCTCTTCCTTCTCTCACTAATATCAGTTCCTATTTACATCATC
ATTATTTTTGCTTTTATGAAGCCCTTTGAAAAGATGAATAACGATGTAATGCAGAGCAATTCCATGGTAAGCTCTGCTAT
TATTGAAGATATCAATGGTGTAGAAACCATCAAATCCCTAACTAGTGAAGAAATTCGATACCAAAAGATTGATAGCGAAT
TCGTGGATTATTTGGACAAATCTTTCAAACTCAGTAAATATTCTATCCTACAGAGCAGCCTTAAACAGGGAGCTCAACTC
ATACTGAATATTGTTATTTTGTGGTTTGGTGCTCAGATAGTTATGACAGGTAAAATTTCCGTTGGACAATTGATTACGTT
TAACACACTCTTATCTTACTTTACTAATCCCTTGGAAAATATCATCAACCTCCAAACAAAACTTCAGTCTGCAAAGGTAG
CCAACAACCGTCTTAATGAAGTTTACTTAGTCGAATCTGAGTTCAAAAATACTCAGACCTTAACTGATTCACCGTTTCTG
GCTGGTGATATTTGTTTTGAAGACATTTCATATAAATATGGTTTTGGACGCGACACCCTAAATAACATAAATCTATCTAT
CAAACAAGGTGATAAGGTCAGTATAGTGGGAATTAGCGGATCAGGGAAAACGACCTTGGCTAAAATGATTGTCAACTTCT
TTGAACCTTACAAGGGACGAATCACTATTAACAACAATGATCTCAAAATGATTGATAAAAAGGTTCTTCGACAACACATC
AACTACCTACCTCAACAAGCTTATATTTTTAGTGGATCAATCTTAGAAAACCTAACCTTGGGAGCTAATCAAATGATTAG
TCAAGAAGATATTATCAAAGCCTGTGAGATAGCAGAAATTCGCCAAGACATCGAACAAATGCCTATGGGATACCAAACAG
AACTATCAGATGGAGCTGGATTATCAGGTGGTCAAAAACAACGGATTGCTTTGGCTAGAGCATTACTGACTAAAGCTCCT
GTACTTATTCTTGATGAAGCAACTAGCGGACTTGATGTTTTAACTGAAAAAAAGGTTATTGAAAATTTGATGGCCATGAC
TGACAAGACCATCATCTTTGTTGCCCATCGTCTTAGTATATCTGAACGAACTAACCAAGTCATTGTCCTTAACCAAGGGA
AAGTTATAGAGACTGGCTCTCATCAAGAATTGATGAGCAAACAAGGTTTCTATCATCATCTATTTAGCAAATAA
ATGACATCTTACAAACGAACCTTTATCCCTCAAATCGACGCTAGGGACTGTGGAGTCGCCGCTTTAGCGTCTATTGCAAA
GTTTTATGGTTCTGACTATTCCTTAGCTCATTTGCGAGAACTAGCTAAAACAAATAAAGAAGGAACGACTGCTCTTGGTA
TCGTCAAAGCAGCCAAAGAAATGAATTTTGAAACAAGAGCTATCCAAGCGGATATGAGCCTCTTTGAAACGGAAGACTTA
CCTTATCCATTTATCGTTCATGTTAATAAAGAGGGCAAACTACAACACTACTACGTTGTCTATCAAAATATAAAAAAATA
TCTTATCATTGGTGATCCTGATCCTACTGTCAAAGTAACAAAAATGACCAAAGAGAGATTTGCTTCCGAATGGACAGGTG
TAGCTATCTTTCTGGCTCCATCTCCCAGCTATAAACCTCATAAGGATAAAAAAAATGGTTTGATGAGCTTTCTCCCCTTA
ATTTTCAAGCAACGCTCACTTATTTTTTATATCATTTTAGCTAGTCTCTTGGTGACTCTTATCAATATTGGTGGCTCATA
CTATCTTCAAGGAATTTTAGATGAATATATTCCTAATCAGATGAAATCAACTCTTGGCATTATCTCCATTGGACTGATTA
TCACCTATATACTTCAACAGATGATGAGTTTCTCACGAGATTACCTCTTGACCGTACTTAGTCAGCGATTAAGTATTGAT
GTGATTCTCTCCTATATTCGCCACATCTTTGAACTTCCTATGTCCTTCTTTGCGACACGGCGAACCGGTGAGGTCATCTC
TCGTTTTACAGATGCCAATTCAATCATTGACGCTCTCGCTTCGACGATTTTGTCACTCTTCCTTGATGTCTCTATATTGT
TCATTATTGGTAGTGTACTTTTGGTACAAAACACCAACCTCTTCCTTCTCTCACTAATATCAGTTCCTATTTACATCATC
ATTATTTTTGCTTTTATGAAGCCCTTTGAAAAGATGAATAACGATGTAATGCAGAGCAATTCCATGGTAAGCTCTGCTAT
TATTGAAGATATCAATGGTGTAGAAACCATCAAATCCCTAACTAGTGAAGAAATTCGATACCAAAAGATTGATAGCGAAT
TCGTGGATTATTTGGACAAATCTTTCAAACTCAGTAAATATTCTATCCTACAGAGCAGCCTTAAACAGGGAGCTCAACTC
ATACTGAATATTGTTATTTTGTGGTTTGGTGCTCAGATAGTTATGACAGGTAAAATTTCCGTTGGACAATTGATTACGTT
TAACACACTCTTATCTTACTTTACTAATCCCTTGGAAAATATCATCAACCTCCAAACAAAACTTCAGTCTGCAAAGGTAG
CCAACAACCGTCTTAATGAAGTTTACTTAGTCGAATCTGAGTTCAAAAATACTCAGACCTTAACTGATTCACCGTTTCTG
GCTGGTGATATTTGTTTTGAAGACATTTCATATAAATATGGTTTTGGACGCGACACCCTAAATAACATAAATCTATCTAT
CAAACAAGGTGATAAGGTCAGTATAGTGGGAATTAGCGGATCAGGGAAAACGACCTTGGCTAAAATGATTGTCAACTTCT
TTGAACCTTACAAGGGACGAATCACTATTAACAACAATGATCTCAAAATGATTGATAAAAAGGTTCTTCGACAACACATC
AACTACCTACCTCAACAAGCTTATATTTTTAGTGGATCAATCTTAGAAAACCTAACCTTGGGAGCTAATCAAATGATTAG
TCAAGAAGATATTATCAAAGCCTGTGAGATAGCAGAAATTCGCCAAGACATCGAACAAATGCCTATGGGATACCAAACAG
AACTATCAGATGGAGCTGGATTATCAGGTGGTCAAAAACAACGGATTGCTTTGGCTAGAGCATTACTGACTAAAGCTCCT
GTACTTATTCTTGATGAAGCAACTAGCGGACTTGATGTTTTAACTGAAAAAAAGGTTATTGAAAATTTGATGGCCATGAC
TGACAAGACCATCATCTTTGTTGCCCATCGTCTTAGTATATCTGAACGAACTAACCAAGTCATTGTCCTTAACCAAGGGA
AAGTTATAGAGACTGGCTCTCATCAAGAATTGATGAGCAAACAAGGTTTCTATCATCATCTATTTAGCAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA/nlmT | Streptococcus mutans UA159 |
72.867 |
99.721 |
0.727 |
| comA | Streptococcus mitis NCTC 12261 |
67.651 |
99.163 |
0.671 |
| comA | Streptococcus mitis SK321 |
67.37 |
99.163 |
0.668 |
| comA | Streptococcus pneumoniae Rx1 |
66.807 |
99.163 |
0.662 |
| comA | Streptococcus pneumoniae D39 |
66.807 |
99.163 |
0.662 |
| comA | Streptococcus pneumoniae R6 |
66.807 |
99.163 |
0.662 |
| comA | Streptococcus pneumoniae TIGR4 |
66.526 |
99.163 |
0.66 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
65.315 |
99.721 |
0.651 |