Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ABKJ27_RS02150 Genome accession   NZ_CP157578
Coordinates   437334..439247 (+) Length   637 a.a.
NCBI ID   WP_410011940.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 432334..444247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS02135 (ABKJ27_02145) fmt 434341..435276 (+) 936 WP_410011938.1 methionyl-tRNA formyltransferase -
  ABKJ27_RS02140 (ABKJ27_02150) rsmB 435269..436582 (+) 1314 WP_410011939.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ABKJ27_RS02145 (ABKJ27_02155) - 436597..437337 (+) 741 WP_033682216.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ABKJ27_RS02150 (ABKJ27_02160) stkP 437334..439247 (+) 1914 WP_410011940.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ABKJ27_RS02155 (ABKJ27_02165) - 439336..440094 (+) 759 WP_049516265.1 threonine/serine exporter family protein -
  ABKJ27_RS02160 (ABKJ27_02170) - 440096..440545 (+) 450 WP_033686494.1 threonine/serine exporter family protein -
  ABKJ27_RS02165 (ABKJ27_02175) - 440659..441831 (+) 1173 WP_049516267.1 hydroxymethylglutaryl-CoA synthase -
  ABKJ27_RS02170 (ABKJ27_02180) - 441831..443105 (+) 1275 WP_410011941.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ABKJ27_RS02175 (ABKJ27_02185) - 443249..444214 (-) 966 WP_000226009.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69537.12 Da        Isoelectric Point: 9.1444

>NTDB_id=1007445 ABKJ27_RS02150 WP_410011940.1 437334..439247(+) (stkP) [Streptococcus sp. KHUD_011]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAIRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVSQSTLTSIPKVQTQSPKPQIV
KPSQQASEDNYATKPVKKRKFRVRYMILLASILLVAASLIWILSRTPATIAIPDVAGQTVAEAKETLKKANFEIGEEKSE
ASEKVEEGRIIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKDKKVPENLIKMEEEESSESEPGTV
LRQTPAAGTTYDLSKASTIVLTVAKKVTSVTMPGYIGSSLEFTKNNLIQIVGVKEANIEVVEVSTAPEGTAEGNVVDQTP
KAGGKIDLASTRIKISIYKPKIPPSSSSSTSVQRGNQGSPTTPNQGNQQGGQQGNQQGTVPTPNQPNSEGNHENSRD

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=1007445 ABKJ27_RS02150 WP_410011940.1 437334..439247(+) (stkP) [Streptococcus sp. KHUD_011]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTCTA
TTTGGCCAAGGATTTGATTTTGGACGGTGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAAACAGATCCTATTG
CAGTGGCTCGTTTTCAGCGGGAAGCGAGAGCCATGGCAGATCTGGACCATCCTCATATCGTTCGGATTACAGATATCGGT
GAAGAAGAGGGACAACAGTATCTCGCAATGGAATATGTTGCTGGATTAGACCTCAAACGCTATATCAAGGAACATCACCC
TCTTTCAAATGAAGAAGCGATTCGAATCATGGGACAAATCCTCTTGGCTATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCGCAAAATATCCTTTTGACCCCAGATGGGACTGCCAAGGTTACAGACTTTGGGATCGCAGTAGCC
TTTGCAGAGACAAGTCTGACTCAGACCAACTCAATGCTAGGTTCCGTTCATTATTTATCGCCAGAGCAGGCCCGTGGTTC
TAAAGCAACTGTGCAGAGTGATATCTATGCAATGGGTATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTACGATG
GGGATAGTGCGGTGACCATCGCCCTCCAGCATTTTCAGAAACCACTGCCATCGGTTATAGCTGAAAATCCATCTGTGCCT
CAGGCTTTAGAAAATGTTGTTATCAAGGCAACTGCCAAGAAATTGACAGATCGCTACAAATCAGTCGCTGAAATGTATGT
GGATTTGTCTAGTAGTTTGTCTTATAATCGTCGTAATGAACCAAAGCTAGTCTTTGACGATGCCACTAAGGCAGATACTA
AGACTCTACCAAAAGTATCCCAGAGCACATTGACCTCAATTCCTAAGGTGCAAACACAAAGTCCGAAGCCACAGATTGTG
AAACCTAGTCAGCAGGCTTCAGAAGACAATTACGCAACCAAGCCTGTTAAGAAACGGAAATTTAGAGTTCGTTATATGAT
TTTGTTGGCCAGCATTCTATTGGTGGCAGCCTCTCTGATTTGGATATTGTCCAGAACTCCTGCAACCATTGCTATTCCAG
ATGTGGCAGGTCAGACAGTTGCGGAGGCTAAGGAAACGCTCAAGAAAGCCAATTTTGAGATTGGTGAGGAGAAATCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACTAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCTTTCCAATTGAGCAATTACGTCGGACGCAAGTATACGGATGTCGTAGCTG
AACTTAAGGATAAGAAGGTTCCTGAAAATCTCATTAAGATGGAAGAGGAAGAATCTAGCGAAAGTGAACCAGGAACGGTT
CTAAGACAAACACCAGCAGCAGGAACTACGTATGACTTATCAAAGGCTAGTACGATTGTTTTAACAGTTGCTAAAAAGGT
AACTAGTGTAACCATGCCGGGTTATATCGGCTCAAGTCTTGAATTCACTAAAAATAATTTGATTCAAATTGTTGGGGTGA
AAGAGGCTAATATTGAAGTTGTTGAAGTGTCAACCGCTCCTGAAGGAACAGCAGAAGGAAATGTTGTGGATCAGACTCCA
AAAGCGGGTGGAAAAATTGATTTAGCCAGCACACGTATTAAAATTTCGATTTATAAACCCAAAATACCACCATCAAGTTC
CTCTTCAACGTCAGTTCAACGTGGTAACCAAGGTTCACCTACTACTCCAAATCAAGGGAATCAACAAGGTGGCCAGCAAG
GAAATCAACAAGGAACGGTTCCTACTCCGAATCAACCAAATAGTGAAGGAAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

79.417

91.523

0.727
  stkP Streptococcus pneumoniae D39

79.074

91.523

0.724
  stkP Streptococcus pneumoniae R6

79.074

91.523

0.724
  stkP Streptococcus pneumoniae Rx1

78.902

91.523

0.722
  pknB Streptococcus mutans UA159

55.232

91.523

0.505
  stkP/pknB Streptococcus salivarius strain HSISS4

52.83

91.523

0.484

Multiple sequence alignment