Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   GPW68_RS00330 Genome accession   NZ_LR738723
Coordinates   55420..56319 (+) Length   299 a.a.
NCBI ID   WP_074389013.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0088     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 50420..61319
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS00310 - 50507..52219 (+) 1713 WP_074389012.1 ABC transporter ATP-binding protein -
  GPW68_RS11480 - 52321..52494 (+) 174 WP_011921669.1 hypothetical protein -
  GPW68_RS00315 ruvB 52789..53790 (+) 1002 WP_024405856.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  GPW68_RS00320 - 53790..54536 (+) 747 WP_024405857.1 GNAT family N-acetyltransferase -
  GPW68_RS00325 - 54538..55173 (+) 636 WP_024405858.1 HAD-IA family hydrolase -
  GPW68_RS00330 comR 55420..56319 (+) 900 WP_074389013.1 helix-turn-helix domain-containing protein Regulator
  GPW68_RS00340 - 56945..57884 (-) 940 Protein_47 IS4 family transposase -
  GPW68_RS00345 - 58024..59244 (+) 1221 WP_074389014.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  GPW68_RS00355 - 59435..60958 (+) 1524 WP_024405860.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35432.37 Da        Isoelectric Point: 4.6995

>NTDB_id=1007009 GPW68_RS00330 WP_074389013.1 55420..56319(+) (comR) [Streptococcus suis isolate GD-0088]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQSK
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=1007009 GPW68_RS00330 WP_074389013.1 55420..56319(+) (comR) [Streptococcus suis isolate GD-0088]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGTG
TAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGAAA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.666

100

0.997
  comR Streptococcus suis 05ZYH33

99.666

100

0.997
  comR Streptococcus suis D9

62.126

100

0.625
  comR Streptococcus mutans UA159

43.478

100

0.435
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371

Multiple sequence alignment