Detailed information NTG1005833

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR35_RS14335
• Genome accession: NZ_CP157310
• Coordinates: 2822123..2823010 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN80
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2817123..2828010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR35_RS14305 (UXR35_014305)	-	2817142..2817234 (+)	93	WP_010956583.1	hypothetical protein	-
UXR35_RS14310 (UXR35_014310)	-	2817342..2817839 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR35_RS14315 (UXR35_014315)	-	2817849..2818109 (-)	261	WP_001789910.1	hypothetical protein	-
UXR35_RS14320 (UXR35_014320)	-	2818491..2818604 (-)	114	WP_001791776.1	hypothetical protein	-
UXR35_RS14325 (UXR35_014325)	-	2819263..2821263 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR35_RS14330 (UXR35_014330)	-	2821260..2822015 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR35_RS14335 (UXR35_014335)	braS	2822123..2823010 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR35_RS14340 (UXR35_014340)	braR	2823021..2823686 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR35_RS14345 (UXR35_014345)	-	2823712..2823912 (-)	201	WP_000604728.1	hypothetical protein	-
UXR35_RS14350 (UXR35_014350)	-	2824110..2825534 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXR35_RS14355 (UXR35_014355)	-	2825594..2825695 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR35_RS14360 (UXR35_014360)	-	2825817..2826272 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR35_RS14365 (UXR35_014365)	-	2826517..2827278 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1005833 UXR35_RS14335 WP_000143419.1 2822123..2823010(-) (braS) [Staphylococcus aureus strain BSN80]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1005833 UXR35_RS14335 WP_000143419.1 2822123..2823010(-) (braS) [Staphylococcus aureus strain BSN80]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997