Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   FGL06_RS00645 Genome accession   NZ_LR594042
Coordinates   98832..99125 (+) Length   97 a.a.
NCBI ID   WP_039697664.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 93832..104125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS00620 (NCTC8133_00123) - 95816..96184 (+) 369 WP_021141429.1 DUF1033 family protein -
  FGL06_RS00625 (NCTC8133_00124) comGA 96253..97194 (+) 942 WP_027968018.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL06_RS00630 (NCTC8133_00125) comGB 97118..98161 (+) 1044 WP_164554342.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL06_RS00635 (NCTC8133_00126) comGC 98161..98463 (+) 303 WP_021141433.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL06_RS00640 (NCTC8133_00127) comGD 98438..98878 (+) 441 WP_126437530.1 competence type IV pilus minor pilin ComGD Machinery gene
  FGL06_RS00645 (NCTC8133_00128) comGE 98832..99125 (+) 294 WP_039697664.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL06_RS00650 (NCTC8133_00129) comGF 99109..99546 (+) 438 WP_126437531.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL06_RS00655 (NCTC8133_00130) comGG 99533..99868 (+) 336 WP_003067902.1 competence type IV pilus minor pilin ComGG Machinery gene
  FGL06_RS00660 (NCTC8133_00131) comGH 99922..100878 (+) 957 WP_024344497.1 class I SAM-dependent methyltransferase Machinery gene
  FGL06_RS00665 (NCTC8133_00132) - 100932..102128 (+) 1197 WP_138083561.1 acetate kinase -
  FGL06_RS00670 (NCTC8133_00133) - 102286..102483 (+) 198 WP_021141442.1 helix-turn-helix transcriptional regulator -
  FGL06_RS00675 (NCTC8133_00134) - 102538..102990 (+) 453 WP_126437532.1 ABC transporter permease -
  FGL06_RS00680 (NCTC8133_00135) - 103002..103637 (+) 636 WP_027968028.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11013.95 Da        Isoelectric Point: 6.8788

>NTDB_id=1005325 FGL06_RS00645 WP_039697664.1 98832..99125(+) (comGE) [Streptococcus equinus strain NCTC8133]
MVIIKRQKLKAYILLESLAALALLATITILVLGEMDKSRHQMQDSLHQQEVLNVATMAVQTGQDDLVMNGVEIHIIRRDG
ELYVYDGQKEVMHVKKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1005325 FGL06_RS00645 WP_039697664.1 98832..99125(+) (comGE) [Streptococcus equinus strain NCTC8133]
GTGGTAATTATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAAAGTTTGGCTGCTTTAGCTCTGCTAGCTACTAT
TACAATCCTTGTTTTGGGAGAAATGGATAAAAGTCGCCACCAGATGCAAGACAGCTTACATCAGCAAGAGGTTCTCAATG
TCGCTACTATGGCTGTTCAAACAGGGCAAGATGACTTGGTGATGAATGGTGTTGAGATTCATATTATTAGGCGTGACGGA
GAACTTTATGTCTATGATGGGCAAAAAGAGGTGATGCATGTTAAGAAGAACTAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

47.917

98.969

0.474
  comGE Streptococcus mutans UA159

47.917

98.969

0.474
  comGE/cglE Streptococcus pneumoniae Rx1

41.935

95.876

0.402
  comGE/cglE Streptococcus pneumoniae D39

41.935

95.876

0.402
  comGE/cglE Streptococcus pneumoniae R6

41.935

95.876

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

41.935

95.876

0.402
  comGE/cglE Streptococcus mitis SK321

40.86

95.876

0.392
  comGE/cglE Streptococcus mitis NCTC 12261

40.86

95.876

0.392