Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   E0F31_RS00200 Genome accession   NZ_LR216064
Coordinates   27592..28941 (+) Length   449 a.a.
NCBI ID   WP_000801591.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 22592..33941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F31_RS00175 (SAMEA3714520_00034) plsX 22710..23702 (+) 993 WP_000717458.1 phosphate acyltransferase PlsX -
  E0F31_RS00180 (SAMEA3714520_00035) - 23708..23941 (+) 234 WP_000136449.1 acyl carrier protein -
  E0F31_RS00185 - 23978..24278 (+) 301 Protein_31 transposase family protein -
  E0F31_RS00190 (SAMEA3714520_00036) blpU 24481..24711 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  E0F31_RS11990 (SAMEA3714520_00037) - 24714..24839 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  E0F31_RS00195 (SAMEA3714520_00038) comA 25426..27579 (+) 2154 WP_000668294.1 peptide cleavage/export ABC transporter ComA Regulator
  E0F31_RS00200 (SAMEA3714520_00039) comB 27592..28941 (+) 1350 WP_000801591.1 competence pheromone export protein ComB Regulator
  E0F31_RS00205 (SAMEA3714520_00040) purC 29111..29818 (+) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  E0F31_RS12145 - 29829..29963 (+) 135 WP_000429436.1 hypothetical protein -
  E0F31_RS00215 (SAMEA3714520_00041) - 30020..33745 (+) 3726 WP_000361217.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49694.60 Da        Isoelectric Point: 5.5684

>NTDB_id=1003932 E0F31_RS00200 WP_000801591.1 27592..28941(+) (comB) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEISLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQIKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1003932 E0F31_RS00200 WP_000801591.1 27592..28941(+) (comB) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTACCCAT
GTCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACATTTGCGGAGAAGGAGATAAGTTTATCAACTAGAGCTACTGTCG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAAGAAAATCCCCAAATTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.441

100

0.984
  comB Streptococcus pneumoniae D39

98.218

100

0.982
  comB Streptococcus pneumoniae R6

98.218

100

0.982
  comB Streptococcus pneumoniae Rx1

98.218

100

0.982
  comB Streptococcus mitis SK321

95.546

100

0.955
  comB Streptococcus mitis NCTC 12261

94.655

100

0.947
  comB Streptococcus gordonii str. Challis substr. CH1

55.778

100

0.559

Multiple sequence alignment