Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AACH63_RS02270 Genome accession   NZ_AP027240
Coordinates   452628..453323 (+) Length   231 a.a.
NCBI ID   WP_017368870.1    Uniprot ID   A0A9Q8Y2F9
Organism   Lactococcus formosensis strain L21-20     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 447628..458323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACH63_RS02245 (LG21E20_04350) - 447845..448546 (+) 702 WP_096368616.1 DeoR/GlpR family DNA-binding transcription regulator -
  AACH63_RS02250 (LG21E20_04360) pfkB 448543..449460 (+) 918 WP_286210758.1 1-phosphofructokinase -
  AACH63_RS02255 (LG21E20_04370) - 449494..451398 (+) 1905 WP_096368615.1 fructose-specific PTS transporter subunit EIIC -
  AACH63_RS02260 (LG21E20_04380) - 451510..451752 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  AACH63_RS02265 (LG21E20_04390) - 451970..452527 (+) 558 WP_096368614.1 YceD family protein -
  AACH63_RS02270 (LG21E20_04400) covR 452628..453323 (+) 696 WP_017368870.1 response regulator transcription factor Regulator
  AACH63_RS02275 (LG21E20_04410) covS 453411..454901 (+) 1491 WP_096368613.1 HAMP domain-containing histidine kinase Regulator
  AACH63_RS02280 (LG21E20_04420) - 455297..456868 (+) 1572 WP_096368612.1 ABC transporter permease subunit -
  AACH63_RS02285 (LG21E20_04430) - 456869..457606 (+) 738 WP_096368611.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27023.75 Da        Isoelectric Point: 5.2713

>NTDB_id=100262 AACH63_RS02270 WP_017368870.1 452628..453323(+) (covR) [Lactococcus formosensis strain L21-20]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTVEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=100262 AACH63_RS02270 WP_017368870.1 452628..453323(+) (covR) [Lactococcus formosensis strain L21-20]
ATGAATTCATCTAAACGTATTTTAATTATCGAGGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGGTATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCGATGTCAAAAGATTACGATTTGATTTTGC
TTGACTTAATGCTCCCAGAACTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATCATG
ATGACTGCACGTGATTCAACAATGGACCGTGTTGCTGGTCTTGATATTGGAGCGGATGATTATATTACAAAACCATTCGC
AATTGAAGAGTTGTTAGCACGTGTGCGTTCACTCTTCCGTCGTGAAGATCATATCCATACTGTTGAAAAGTCAGACAACA
CTTCATTCCGTGACTTGGTAATTGATAAAACAAACCGCACAGTACACCGTGGTAAAAAAGTCATTGACCTTACACGTCGT
GAGTACGACTTACTCTTGACTTTGATGCAAAATGTGGGGGATGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGTTACCTACGTAACAAGATTGATGTCGAAGGCCGTG
AAAGTTATATCCAAACTGTTCGTGGCATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-116)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.646

99.134

0.879
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424

Multiple sequence alignment