Detailed information NTG0100263

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: AACH63_RS02275
• Genome accession: NZ_AP027240
• Coordinates: 453411..454901 (+)
• Length: 496 a.a.
• NCBI ID: WP_096368613.1
• Uniprot ID: -
• Organism: Lactococcus formosensis strain L21-20
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 448411..459901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AACH63_RS02250 (LG21E20_04360)	pfkB	448543..449460 (+)	918	WP_286210758.1	1-phosphofructokinase	-
AACH63_RS02255 (LG21E20_04370)	-	449494..451398 (+)	1905	WP_096368615.1	fructose-specific PTS transporter subunit EIIC	-
AACH63_RS02260 (LG21E20_04380)	-	451510..451752 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
AACH63_RS02265 (LG21E20_04390)	-	451970..452527 (+)	558	WP_096368614.1	YceD family protein	-
AACH63_RS02270 (LG21E20_04400)	covR	452628..453323 (+)	696	WP_017368870.1	response regulator transcription factor	Regulator
AACH63_RS02275 (LG21E20_04410)	covS	453411..454901 (+)	1491	WP_096368613.1	HAMP domain-containing histidine kinase	Regulator
AACH63_RS02280 (LG21E20_04420)	-	455297..456868 (+)	1572	WP_096368612.1	ABC transporter permease subunit	-
AACH63_RS02285 (LG21E20_04430)	-	456869..457606 (+)	738	WP_096368611.1	amino acid ABC transporter ATP-binding protein	-
AACH63_RS02290 (LG21E20_04440)	murD	457745..459106 (+)	1362	WP_096368610.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56905.89 Da
• Isoelectric Point: 5.2104

>NTDB_id=100263 AACH63_RS02275 WP_096368613.1 453411..454901(+) (covS) [Lactococcus formosensis strain L21-20]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMRALNNVEQSLSQSVNKLS
EENLANYLAYAKGYTASSQGRENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFRLRKDVGDSSQAVRTFGEYSGYLV
ERPVHSKKTGELIGYVQAFYDMSYYYSVRTKLLVALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLSVLDGHLNLLNRWGKNDPEVLEESLQSSIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLKLTVENDLPSGRLAHIYPNHYEQGLKILIDNAI
KYSPEDRQEVKIHLEEDDEYIITTVGDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYEGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=100263 AACH63_RS02275 WP_096368613.1 453411..454901(+) (covS) [Lactococcus formosensis strain L21-20]
ATGGTAAAATTTTTTGATTCTAAGAAGAAAAAAACAGAAAGTCTTCCAGAGCGTAAGCGGAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACTTTCACTATTTTTACAGTATTGGTTTATCAACTAACGATAACTACTTTCA
TCAATTCTGAAAAAGAGGATATGATGAGGGCTTTAAATAATGTTGAACAAAGTCTGTCCCAATCGGTAAACAAACTGTCA
GAAGAAAATCTTGCGAATTATTTGGCTTATGCCAAAGGCTATACAGCCTCCAGTCAGGGAAGAGAAAATGAACTTGAAAC
ACTAGGAAGTATGATTGGTTCAAGAAAGTCCTTTTATGTCTTCGATGTAGGTGAGAACCTGATTTACTCGACCAATTCGT
ATGGTTTTCGTCTAAGGAAAGATGTGGGTGATTCATCGCAAGCTGTACGTACATTTGGCGAATATTCTGGTTATTTGGTT
GAGCGACCCGTGCATTCTAAAAAAACGGGTGAACTGATCGGCTATGTACAGGCTTTTTATGATATGAGCTATTATTATAG
TGTGCGTACAAAGCTACTTGTTGCCTTGATTATCTTAGAAATTATAGCTCTCTTTATAGCTCAGTTTGTTGGTTACTTTA
TGGCGAGTCGCTATATCAAGCCTTTGGAACGTTTGCACGATGCAATCACTACACGTGCCAATAATTTGAAAGCAGATTTC
AAACCTGTCGTTATTCAGACAGGGGATGAAATTGAGGAACTTGCAACAGTTTATAATGATATGATGATCAAGCTTAATGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCCGATGTCAGTCATGAGTTACGGACGCCACTTTCAGTTTTGGATGGGCATT
TGAATCTCTTGAATCGTTGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGTCCAGTATAGAAGAAGTTAGT
ACGATGAGAACGATGTTGGAAGAGATGCTCGCATTGGCGCGTCTTGAAAGCATTGATTTTCAAGATGAAGACCTAATCTG
TGATCCGACAGAAGTTTCGAATTTTCTTAAGAAAAATTTTCTACTCATCCATCCTGATTTAAAGTTAACTGTTGAAAATG
ACTTGCCATCAGGAAGATTAGCACATATATATCCCAACCATTATGAGCAAGGTTTGAAAATATTGATTGATAATGCGATA
AAATACTCGCCTGAAGATCGTCAAGAAGTCAAGATACATCTTGAAGAAGATGATGAATATATCATTACAACTGTGGGGGA
CCGTGGTTATGGTATTAGCCAAGAAGATTTAAAACATGTATTTGAACGTTTCTTCCGTGCGGATAAAGCACGAAATCGAG
ATATAGGAGGAACTGGGCTTGGGCTATCTATTATTCAACGTATAGTGGAGAACTATGAGGGAGATGTTAGCGTGACTTCC
GTTGTAGGAGAGGGTTCAAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.131	100	0.552