Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AACH29_RS09235 Genome accession   NZ_AP027239
Coordinates   1824336..1825553 (+) Length   405 a.a.
NCBI ID   WP_003133516.1    Uniprot ID   A0A3D4RHV6
Organism   Lactococcus garvieae strain L21-12     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1819336..1830553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACH29_RS09205 (LG21E12_18020) eeP 1819347..1820594 (-) 1248 WP_014025467.1 RIP metalloprotease RseP Regulator
  AACH29_RS09210 (LG21E12_18030) - 1820770..1821564 (-) 795 WP_003133509.1 phosphatidate cytidylyltransferase -
  AACH29_RS09215 (LG21E12_18040) - 1821561..1822298 (-) 738 WP_003133511.1 isoprenyl transferase -
  AACH29_RS09220 (LG21E12_18050) yajC 1822499..1822834 (-) 336 WP_014025468.1 preprotein translocase subunit YajC -
  AACH29_RS09225 (LG21E12_18060) - 1822909..1823556 (-) 648 WP_014025469.1 DNA alkylation repair protein -
  AACH29_RS09230 (LG21E12_18070) rlmH 1823553..1824032 (-) 480 WP_003133515.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AACH29_RS09235 (LG21E12_18080) htrA 1824336..1825553 (+) 1218 WP_003133516.1 trypsin-like peptidase domain-containing protein Regulator
  AACH29_RS09240 (LG21E12_18090) - 1825651..1826649 (+) 999 WP_014025471.1 glycosyltransferase -
  AACH29_RS09245 (LG21E12_18100) - 1826662..1827996 (+) 1335 WP_014025472.1 glycosyltransferase family 4 protein -
  AACH29_RS09250 (LG21E12_18110) - 1828047..1828271 (+) 225 WP_003133519.1 DUF1797 family protein -
  AACH29_RS09255 (LG21E12_18120) - 1828296..1829345 (-) 1050 WP_014025473.1 BMP family protein -
  AACH29_RS09260 (LG21E12_18130) - 1829505..1830254 (-) 750 WP_014025474.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41787.63 Da        Isoelectric Point: 4.8808

>NTDB_id=100236 AACH29_RS09235 WP_003133516.1 1824336..1825553(+) (htrA) [Lactococcus garvieae strain L21-12]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNDSNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSGSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=100236 AACH29_RS09235 WP_003133516.1 1824336..1825553(+) (htrA) [Lactococcus garvieae strain L21-12]
ATGGCAAAGAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGTGGTAGTGCTATCTA
CCAAAACATGACCAATACACCATCATCTAATAACACTTCGGACAATTCTGTAAGTACGGTTAACGTCCAAGTCAATACAG
ATACCACCAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTCGGTGGAGGCGATACAAGCAGCAATGACAGTAACACGCCCCAGCTGGCTGGTGAAGGTTCTGGTGT
TATTTATAAAAAAGATGGCAATACAGCATACATCGTCACCAACTATCACGTGATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCTGGCGGTCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGTAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTTGGTTC
TCCTCTTGGAAGTGAGTATGCCAACTCAGCAACGGAAGGGATTGTTTCAAGTCTTAATCGTAATGTTACGCTGCAAAACA
GCCAAGGCCAAACAATTAATGTGAACGCAATTCAAACCGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCACTCATA
AATATTCAGGGACAAGTCATCGGGATTACTTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCGGCAGTGGTGTCTC
TGTAGAAGGAATGGGCTTTGCGATACCAGCCAATGATGTGGTCAATATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCACAAAATATGTTGGCTTCACTTAATCTTCCTGAA
AATGTGACAAATGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGTGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTGAACCTTCAAAGTACACTTTATAAGTCATCGATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTGCGAATATCAAGTTGGATAAGACAAGTAGTGACATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

PDZ domain (PDZ_2)

(296-392)

Peptidase family M50 (Peptidase_M50)

(294-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3D4RHV6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

53.634

98.519

0.528
  htrA Streptococcus pneumoniae Rx1

53.383

98.519

0.526
  htrA Streptococcus pneumoniae D39

53.383

98.519

0.526
  htrA Streptococcus pneumoniae R6

53.383

98.519

0.526
  htrA Streptococcus pneumoniae TIGR4

53.383

98.519

0.526
  htrA Streptococcus mutans UA159

56.085

93.333

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

96.543

0.523

Multiple sequence alignment