Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   ABC807_RS05230 Genome accession   NZ_CP156625
Coordinates   967099..967803 (+) Length   234 a.a.
NCBI ID   WP_000722076.1    Uniprot ID   Q9S1K0
Organism   Streptococcus pneumoniae strain TL7/1993     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 962099..972803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC807_RS05205 (ABC807_05205) coaC 962388..962939 (-) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -
  ABC807_RS05210 (ABC807_05210) coaB 962951..963640 (-) 690 WP_000699494.1 phosphopantothenate--cysteine ligase -
  ABC807_RS05215 (ABC807_05215) - 963870..965540 (+) 1671 WP_000845285.1 formate--tetrahydrofolate ligase -
  ABC807_RS05220 (ABC807_05220) - 965646..965771 (-) 126 WP_001818232.1 hypothetical protein -
  ABC807_RS05225 (ABC807_05225) mutY 965868..967043 (+) 1176 WP_000886152.1 A/G-specific adenine glycosylase -
  ABC807_RS05230 (ABC807_05230) micA 967099..967803 (+) 705 WP_000722076.1 response regulator YycF Regulator
  ABC807_RS05235 (ABC807_05235) micB 967796..969145 (+) 1350 WP_000886213.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ABC807_RS05240 (ABC807_05240) vicX 969147..969956 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  ABC807_RS05245 (ABC807_05245) - 970020..971276 (-) 1257 WP_000530078.1 ISL3 family transposase -
  ABC807_RS05250 (ABC807_05250) relB 971470..971712 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  ABC807_RS05255 (ABC807_05255) - 971714..971968 (+) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  ABC807_RS05260 (ABC807_05260) - 972015..972758 (+) 744 Protein_990 ion channel -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=1001844 ABC807_RS05230 WP_000722076.1 967099..967803(+) (micA) [Streptococcus pneumoniae strain TL7/1993]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1001844 ABC807_RS05230 WP_000722076.1 967099..967803(+) (micA) [Streptococcus pneumoniae strain TL7/1993]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 1NXS
  PDB 2A9O
  PDB 2A9P

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment