ICEberg
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ICE family: ICESa2603
ICESa2603 is a well studied ICE. We selected it as a reference and defined ICESa2603 family. We classified any ICE that encodes an integrase gene closely related to int(ICESa2603), defined as over 60% protein homology and that has significant sequence alignment and syntenic 'core' structure into the this family.

#IDICE nameStrainReplicon
176 experimental ICESde3396Streptococcus dysgalactiae subsp. equisimilis NS3396-
2233 in_silico ICESsu(BM407)2Streptococcus suis BM407NC_012926
3234 in_silico ICESsu(SC84)Streptococcus suis SC84NC_012924
4311 experimental ICESsu05ZYH33-1Streptococcus suis 05ZYH33NC_009442
5313 in_silico ICESsu98HAH33-1Streptococcus suis 98HAH33NC_009443
6377 experimental ICESa2603Streptococcus agalactiae 2603V/RNC_004116
7378 in_silico ICESdy12394-1Streptococcus dysgalactiae subsp. equisimilis ATCC 12394CP002215
8379 in_silico ICESthJIM8232-1Streptococcus thermophilus JIM 8232FR875178
9380 in_silico ICESpa43144-1Streptococcus pasteurianus ATCC 43144NC_015600
10445 experimental ICESsu32457Streptococcus suis 32457-
11786 in_silico ICESa09mas018883Streptococcus agalactiae 09mas018883-
12791 experimental ICESag37Streptococcus agalactiae Sag37
13805 experimental ICESde3396-likeStreptococcus dysgalactiae subsp. equisimilis (Sde5580)-
14827 experimental ICESpy009Streptococcus pyogenes MB56Spyo009-
15831 in_silico ICESsuD9Streptococcus suis D9-
16832 experimental ICESsuHB1011Streptococcus suis HB1011-
17838 in_silico ICESsuSS12Streptococcus suis SS12-
18839 in_silico ICESsuT15Streptococcus suis T15-
experimental Data derived from experimental literature
in_silico Putative ICEs predicted by bioinformatic methods
(1) Zhou K et al. (2017). ICESag37, a Novel Integrative and Conjugative Element Carrying Antimicrobial Resistance Genes and Potential Virulence Factors in Streptococcus agalactiae. Front Microbiol. 1.667361111. [PudMed:29051752]
(2) Del Grosso M et al. (2016). ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. Antimicrob Agents Chemother. 60(7):3906-12. [PudMed:27067338] in_silico
(3) Huang J et al. (2016). Comparative Genomic Analysis of the ICESa2603 Family ICEs and Spread of erm(B)- and tet(O)-Carrying Transferable 89K-Subtype ICEs in Swine and Bovine Isolates in China. Front Microbiol. 7:55. [PudMed:26870017]
(4) Zubair S et al. (2013). Genome Sequence of Streptococcus agalactiae Strain 09mas018883, Isolated from a Swedish Cow. Genome Announc. 1(4). [PudMed:23846269]
(5) Palmieri C et al. (2012). Interspecies mobilization of an erm(T)-carrying plasmid of Streptococcus dysgalactiae subsp. equisimilis by a coresident ICE of the ICESa2603 family. J Antimicrob Chemother. . [PudMed:22949621] experimental
(6) Palmieri C et al. (2012). Characterization of a Streptococcus suis tet(O/W/32/O)-carrying element transferable to major streptococcal pathogens. Antimicrob Agents Chemother. 56(9):4697-702. [PudMed:22710115] experimental
(7) Palmieri C et al. (2011). Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen. Front Microbiol. 0.246527778. [PudMed:22275909]
(8) Zhang A et al. (2011). Comparative genomic analysis of Streptococcus suis reveals significant genomic diversity among different serotypes. BMC Genomics. 0.863194444. [PudMed:22026465]
(9) Haenni M et al. (2010). Diversity and mobility of integrative and conjugative elements in bovine isolates of Streptococcus agalactiae, S. dysgalactiae subsp. dysgalactiae, and S. uberis. Appl Environ Microbiol. 76(24):7957-65. [PudMed:20952646] experimental
(10) Holden MT et al. (2009). Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis. PLoS One. 4(7):e6072. [PudMed:19603075]
(11) Davies MR et al. (2009). A novel integrative conjugative element mediates genetic transfer from group G Streptococcus to other {beta}-hemolytic Streptococci. J Bacteriol. 191(7):2257-65. [PudMed:19168609] experimental
(12) Tettelin H et al. (2002). Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A. 99(19):12391-6. [PudMed:12200547]
 
experimental experimental literature
in_silico in silico analysis literature