I. Information of ICE

ICEberg ID	233
Name	ICESsu(BM407)2
Organism	Streptococcus suis BM407
Size (bp)	80320
GC content [Genome] (%)	37.11[41.06]
Insertion site	the 3' end of 50S rDNA (SSUBM407_0933)
Function	Tetracycline and streptomycin resistance
Species that ICE can be transferred to	-
Nucleotide Sequence	FM252032 (complete ICE sequence in this genome)
Replicon	chromosome (2146229 bp, BioProject:32237) [NC_012926]
Genome coordinates	1005794..1086113
Putative oriT region	-
Putative relaxase	coordinates: 1068244..1069506; Locus tag: SSUBM407_0973;  Family:  MOBV

II. ICE interaction with IME/CIME/

The interaction information of ICESsu(BM407)2 is not available.

The graph information of ICESsu(BM407)2 components from FM252032
Complete gene list of ICESsu(BM407)2 from FM252032
#	Gene	Coordinates [+/-], size (bp)	Product  (GenBank annotation)	*Reannotation
1	SSUBM407_0930	1001264..1002106 [+], 843	SMF family protein
2	topA	1002199..1004292 [+], 2094	DNA topoisomerase I
3	rplJ	1004869..1005363 [+], 495	50S ribosomal protein L10
4	rplL	1005429..1005794 [+], 366	50S ribosomal protein L7/L12
5	SSUBM407_0933a	1005993..1006166 [+], 174	hypothetical protein
6	SSUBM407_0934	1006163..1006981 [+], 819	replication initiator protein A protein
7	SSUBM407_0935	1007130..1008485 [+], 1356	C-5 cytosine-specific DNA methylase
8	SSUBM407_0936	1008469..1008897 [+], 429	hypothetical protein
9	SSUBM407_0937	1008908..1009291 [+], 384	hypothetical protein
10	SSUBM407_0938	1009300..1009533 [+], 234	hypothetical protein
11	SSUBM407_0939	1009536..1010120 [+], 585	CAAX amino terminal protease family protein
12	SSUBM407_0940	1010198..1010686 [+], 489	hypothetical protein
13	SSUBM407_0941	1010686..1012503 [+], 1818	putative conjugal transfer protein TraG
14	SSUBM407_0942	1012521..1012763 [+], 243	putative membrane protein
15	SSUBM407_0943	1012782..1013636 [+], 855	putative TrbL/VirB6 plasmid conjugal transfer protein
16	SSUBM407_0944	1013698..1014051 [+], 354	putative membrane protein
17	SSUBM407_0945	1014029..1016359 [+], 2331	hypothetical protein	PrgJ, T4SS component
18	SSUBM407_0946	1016361..1019162 [+], 2802	hypothetical protein	PrgK, T4SS component
19	SSUBM407_0947	1019224..1020069 [-], 846	hypothetical protein
20	SSUBM407_0948	1020066..1020656 [-], 591	hypothetical protein
21	SSUBM407_0949	1020937..1025832 [+], 4896	putative glucan-binding surface-anchored protein	PrgB, T4SS component
22	SSUBM407_0949a	1025833..1026024 [+], 192	hypothetical protein
23	SSUBM407_0950	1026008..1026559 [+], 552	hypothetical protein
24	SSUBM407_0951	1026609..1030454 [+], 3846	hypothetical protein (fragment)
25	SSUBM407_0951a	1030458..1030832 [+], 375	hypothetical protein (fragment)
26	ermB	1031089..1031826 [+], 738	rRNA adenine N-6-methyltransferase
27	SSUBM407_0953	1032298..1032672 [+], 375	hypothetical protein
28	tetO	1033039..1034958 [+], 1920	tetracycline resistance protein TetO
29	SSUBM407_0954a	1035250..1035327 [-], 78	putative adenine phosphoribosyltransferase (fragment)
30	aadE	1035371..1036234 [-], 864	streptomycin adenylyltransferase
31	SSUBM407_0956	1036267..1036950 [-], 684	putative methyltransferase
32	SSUBM407_0957	1037077..1037550 [-], 474	dihydrofolate reductase
33	SSUBM407_0958	1037653..1038678 [-], 1026	putative transposase
34	SSUBM407_0959	1038786..1039655 [-], 870	hypothetical protein
35	SSUBM407_0960	1039670..1039894 [-], 225	putative DNA-binding protein
36	SSUBM407_0960a	1040037..1040117 [-], 81	DNA recombinase (fragment)
37	SSUBM407_0960b	1040118..1040168 [+], 51	putative membrane protein (fragment)
38	SSUBM407_0960c	1040172..1040201 [+], 30	two-component sensor histidine kinase (fragment)
39	SSUBM407_0961a	1040599..1041102 [-], 504	transposase (fragment)
40	SSUBM407_0961	1041609..1042247 [+], 639	putative exported protein	PrgL, T4SS component
41	SSUBM407_0962	1042286..1043362 [+], 1077	DNA primase
42	SSUBM407_0963	1043416..1043643 [+], 228	hypothetical protein
43	SSUBM407_0964	1043640..1044029 [+], 390	hypothetical protein
44	SSUBM407_0965	1044016..1044369 [+], 354	hypothetical protein
45	SSUBM407_0966	1044439..1044915 [+], 477	antidote epsilon protein
46	SSUBM407_0967	1044915..1045691 [+], 777	zeta-toxin
47	SSUBM407_0968	1045688..1047775 [+], 2088	hypothetical protein
48	SSUBM407_0969	1047762..1049579 [+], 1818	DNA helicase
49	SSUBM407_0990	1049673..1074215 [-], 24543	putative ATP-binding protein (pseudogene)
50	SSUBM407_0970	1050335..1050649 [+], 315	hypothetical protein
51	SSUBM407_0971	1050665..1051051 [+], 387	hypothetical protein
52	SSUBM407_0972	1051080..1052462 [+], 1383	FtsK/SpoIIIE family protein	Orf21_Tn, T4SS component
53	SSUBM407_0973	1052641..1053846 [+], 1206	replication initiation factor	Relaxase, MOBT Family
54	SSUBM407_0974	1053889..1054110 [+], 222	putative membrane protein	Orf19_Tn, T4SS component
55	SSUBM407_0975	1054227..1054724 [+], 498	antirestriction protein
56	SSUBM407_0976	1054699..1055205 [+], 507	putative membrane protein	Orf17_Tn, T4SS component
57	SSUBM407_0977	1055189..1057636 [+], 2448	hypothetical protein	Orf16_Tn, T4SS component
58	SSUBM407_0978	1057639..1061887 [+], 4249	putative membrane protein (pseudogene)
59	SSUBM407_0979	1059554..1060600 [+], 1047	putative transposase
60	cat	1060737..1061360 [+], 624	chloramphenicol acetyltransferase
61	SSUBM407_0981	1061884..1062885 [+], 1002	putative exported protein	Orf14_Tn, T4SS component
62	SSUBM407_0982	1062882..1063814 [+], 933	putative membrane protein	Orf13_Tn, T4SS component
63	tetM2	1064191..1066110 [+], 1920	tetracycline resistance protein TetM 2
64	tetL	1066304..1067680 [+], 1377	tetracycline resistance protein TetL
65	pre	1068244..1069506 [+], 1263	plasmid recombination enzyme type 2	Relaxase, MOBV Family
66	SSUBM407_0986	1069781..1070080 [-], 300	putative DNA-binding protein (fragment)
67	SSUBM407_0987	1070585..1071007 [+], 423	putative DNA-binding protein
68	SSUBM407_0987a	1071004..1071234 [+], 231	hypothetical protein
69	SSUBM407_0988	1071695..1071898 [+], 204	excisionase
70	SSUBM407_0989	1071980..1073197 [+], 1218	integrase	Integrase
71	SSUBM407_0991	1074580..1074945 [+], 366	hypothetical protein
72	SSUBM407_0992	1074945..1075310 [+], 366	putative mobilisation protein
73	SSUBM407_0993	1075297..1077162 [+], 1866	relaxase
74	SSUBM407_0995	1077725..1079824 [+], 2100	ABC transporter ATP-binding membrane protein
75	SSUBM407_0996	1079837..1080553 [+], 717	putative ABC transporter ATP-binding protein
76	SSUBM407_0997	1080546..1081334 [+], 789	membrane protein
77	SSUBM407_0998	1081331..1082038 [+], 708	membrane protein
78	SSUBM407_0999	1082069..1082752 [+], 684	response regulator protein
79	SSUBM407_1000	1082737..1083834 [+], 1098	sensor histidine kinase
80	SSUBM407_1001	1084164..1084385 [+], 222	transcriptional regulator, Cro/CI family
81	SSUBM407_1002	1084664..1084891 [+], 228	hypothetical protein
82	SSUBM407_1003	1084914..1086113 [+], 1200	tyrosine family site-specific integrase
83	SSUBM407_1004	1086298..1087047 [+], 750	haloacid dehalogenase-like hydrolase
84	SSUBM407_1005	1087243..1088577 [+], 1335	protein Gid homolog
85	SSUBM407_1006	1088651..1089490 [+], 840	AraC family regulatory protein
86	SSUBM407_1007	1089555..1090559 [+], 1005	conserved hypothetical protein

Flanking regions

(1) Palmieri C; Varaldo PE; Facinelli B (2011). Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen. Front Microbiol. 0.246527778. [PubMed:22275909]

(2) Holden MT; Hauser H; Sanders M; Ngo TH; Cherevach I; Cronin A; Goodhead I; Mungall K; Quail MA; Price C; Rabbinowitsch E; Sharp S; Croucher NJ; Chieu TB; Mai NT; Diep TS; Chinh NT; Kehoe M; Leigh JA; Ward PN; Dowson CG; Whatmore AM; Chanter N; Iversen P; Gottschalk M; Slater JD; Smith HE; Spratt BG; Xu J; Ye C; Bentley S; Barrell BG; Schultsz C; Maskell DJ; Parkhill J (2009). Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis. PLoS One. 4(7):e6072. [PubMed:19603075]