Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2087101..2087246 Replicon chromosome
Accession NZ_AP023315
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4614

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2087141..2087244 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2087101..2087246 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5684_RS10160 2083527..2084225 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5684_RS10165 2084249..2084905 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5684_RS10170 2085013..2085243 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5684_RS10175 2085381..2085755 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5684_RS10180 2085756..2086631 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5684_RS10185 2086648..2087001 + 354 WP_000722368.1 YebY family protein -
- 2087101..2087246 - 146 - - Antitoxin
- 2087141..2087244 + 104 - - Toxin
K5684_RS10190 2087375..2088298 - 924 Protein_2004 tyrosine-type recombinase/integrase -
K5684_RS25225 2088562..2089023 - 462 Protein_2005 DNA breaking-rejoining protein -
K5684_RS10200 2089012..2089203 + 192 Protein_2006 glycoside hydrolase family 19 protein -
K5684_RS10205 2089257..2089790 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5684_RS10210 2090047..2090214 - 168 WP_000789530.1 lytic enzyme -
K5684_RS10215 2090279..2090467 - 189 WP_001521334.1 hypothetical protein -
K5684_RS10220 2090522..2090782 + 261 Protein_2010 DUF1441 family protein -
K5684_RS10225 2090997..2091341 + 345 Protein_2011 macro domain-containing protein -
K5684_RS10230 2091351..2091821 + 471 Protein_2012 tail fiber assembly protein -
K5684_RS10235 2091918..2092118 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2081441..2119757 38316


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37532 NZ_AP023315:2087141-2087244 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37532 NZ_AP023315:c2087246-2087101 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References