Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2079197..2079342 Replicon chromosome
Accession NZ_AP023313
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4605

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2079237..2079340 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2079197..2079342 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5670_RS10105 2075623..2076321 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5670_RS10110 2076345..2077001 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5670_RS10115 2077109..2077339 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5670_RS10120 2077477..2077851 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5670_RS10125 2077852..2078727 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5670_RS10130 2078744..2079097 + 354 WP_000722368.1 YebY family protein -
- 2079197..2079342 - 146 - - Antitoxin
- 2079237..2079340 + 104 - - Toxin
K5670_RS10135 2079471..2080394 - 924 Protein_1991 tyrosine-type recombinase/integrase -
K5670_RS24490 2080658..2081119 - 462 Protein_1992 DNA breaking-rejoining protein -
K5670_RS10145 2081108..2081299 + 192 Protein_1993 glycoside hydrolase family 19 protein -
K5670_RS10150 2081353..2081886 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5670_RS10155 2082143..2082310 - 168 WP_000789530.1 lytic enzyme -
K5670_RS10160 2082375..2082563 - 189 WP_001521334.1 hypothetical protein -
K5670_RS10165 2082618..2082878 + 261 Protein_1997 DUF1441 family protein -
K5670_RS10170 2083093..2083437 + 345 Protein_1998 macro domain-containing protein -
K5670_RS10175 2083447..2083917 + 471 Protein_1999 tail fiber assembly protein -
K5670_RS10180 2084014..2084214 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2073537..2111853 38316


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37503 NZ_AP023313:2079237-2079340 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37503 NZ_AP023313:c2079342-2079197 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References