Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2059719..2059864 Replicon chromosome
Accession NZ_AP023309
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4578

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2059759..2059862 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2059719..2059864 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5680_RS09975 2056145..2056843 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5680_RS09980 2056867..2057523 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5680_RS09985 2057631..2057861 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5680_RS09990 2057999..2058373 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5680_RS09995 2058374..2059249 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5680_RS10000 2059266..2059619 + 354 WP_000722368.1 YebY family protein -
- 2059719..2059864 - 146 - - Antitoxin
- 2059759..2059862 + 104 - - Toxin
K5680_RS10005 2059993..2060916 - 924 Protein_1966 tyrosine-type recombinase/integrase -
K5680_RS25030 2061180..2061641 - 462 Protein_1967 DNA breaking-rejoining protein -
K5680_RS10015 2061630..2061821 + 192 Protein_1968 glycoside hydrolase family 19 protein -
K5680_RS10020 2061875..2062408 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5680_RS10025 2062665..2062832 - 168 WP_000789530.1 lytic enzyme -
K5680_RS10030 2062897..2063085 - 189 WP_001521334.1 hypothetical protein -
K5680_RS10035 2063140..2063400 + 261 Protein_1972 DUF1441 family protein -
K5680_RS10040 2063615..2063959 + 345 Protein_1973 macro domain-containing protein -
K5680_RS10045 2063969..2064439 + 471 Protein_1974 tail fiber assembly protein -
K5680_RS10050 2064536..2064736 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2054059..2092375 38316


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37454 NZ_AP023309:2059759-2059862 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37454 NZ_AP023309:c2059864-2059719 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References