Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2087018..2087163 Replicon chromosome
Accession NZ_AP023294
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4261

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2087058..2087161 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2087018..2087163 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5635_RS10150 2083444..2084142 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5635_RS10155 2084166..2084822 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5635_RS10160 2084930..2085160 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5635_RS10165 2085298..2085672 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5635_RS10170 2085673..2086548 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5635_RS10175 2086565..2086918 + 354 WP_000722368.1 YebY family protein -
- 2087018..2087163 - 146 - - Antitoxin
- 2087058..2087161 + 104 - - Toxin
K5635_RS10180 2087292..2088215 - 924 Protein_2001 tyrosine-type recombinase/integrase -
K5635_RS24395 2088479..2088940 - 462 Protein_2002 DNA breaking-rejoining protein -
K5635_RS10190 2088929..2089120 + 192 Protein_2003 glycoside hydrolase family 19 protein -
K5635_RS10195 2089174..2089707 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5635_RS10200 2089964..2090131 - 168 WP_000789530.1 lytic enzyme -
K5635_RS10205 2090196..2090384 - 189 WP_001521334.1 hypothetical protein -
K5635_RS10210 2090439..2090699 + 261 Protein_2007 DUF1441 family protein -
K5635_RS10215 2090914..2091258 + 345 Protein_2008 macro domain-containing protein -
K5635_RS10220 2091268..2091738 + 471 Protein_2009 tail fiber assembly protein -
K5635_RS10225 2091835..2092035 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2081358..2119674 38316


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37295 NZ_AP023294:2087058-2087161 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37295 NZ_AP023294:c2087163-2087018 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References