Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2087734..2087879 Replicon chromosome
Accession NZ_AP023292
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4233

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2087774..2087877 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2087734..2087879 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5617_RS10160 2084160..2084858 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5617_RS10165 2084882..2085538 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5617_RS10170 2085646..2085876 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5617_RS10175 2086014..2086388 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5617_RS10180 2086389..2087264 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5617_RS10185 2087281..2087634 + 354 WP_000722368.1 YebY family protein -
- 2087734..2087879 - 146 - - Antitoxin
- 2087774..2087877 + 104 - - Toxin
K5617_RS10190 2088008..2088931 - 924 Protein_2002 tyrosine-type recombinase/integrase -
K5617_RS24015 2089195..2089656 - 462 Protein_2003 DNA breaking-rejoining protein -
K5617_RS10200 2089645..2089836 + 192 Protein_2004 glycoside hydrolase family 19 protein -
K5617_RS10205 2089890..2090423 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5617_RS10210 2090680..2090847 - 168 WP_000789530.1 lytic enzyme -
K5617_RS10215 2090912..2091100 - 189 WP_001521334.1 hypothetical protein -
K5617_RS10220 2091155..2091415 + 261 Protein_2008 DUF1441 family protein -
K5617_RS10225 2091630..2091974 + 345 Protein_2009 macro domain-containing protein -
K5617_RS10230 2091984..2092454 + 471 Protein_2010 tail fiber assembly protein -
K5617_RS10235 2092551..2092751 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2082074..2120390 38316


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37271 NZ_AP023292:2087774-2087877 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37271 NZ_AP023292:c2087879-2087734 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References