Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2114216..2114361 Replicon chromosome
Accession NZ_AP023291
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain L-4126

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2114256..2114359 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2114216..2114361 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5613_RS10255 2110642..2111340 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5613_RS10260 2111364..2112020 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5613_RS10265 2112128..2112358 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5613_RS10270 2112496..2112870 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5613_RS10275 2112871..2113746 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5613_RS10280 2113763..2114116 + 354 WP_000722368.1 YebY family protein -
- 2114216..2114361 - 146 - - Antitoxin
- 2114256..2114359 + 104 - - Toxin
K5613_RS10285 2114490..2115413 - 924 Protein_2022 tyrosine-type recombinase/integrase -
K5613_RS24300 2115677..2116138 - 462 Protein_2023 DNA breaking-rejoining protein -
K5613_RS10295 2116127..2116318 + 192 Protein_2024 glycoside hydrolase family 19 protein -
K5613_RS10300 2116372..2116905 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5613_RS10305 2117162..2117329 - 168 WP_000789530.1 lytic enzyme -
K5613_RS10310 2117394..2117582 - 189 WP_001521334.1 hypothetical protein -
K5613_RS10315 2117637..2117897 + 261 Protein_2028 DUF1441 family protein -
K5613_RS10320 2118112..2118456 + 345 Protein_2029 macro domain-containing protein -
K5613_RS10325 2118466..2118936 + 471 Protein_2030 tail fiber assembly protein -
K5613_RS10330 2119033..2119233 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2108556..2136556 28000


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37247 NZ_AP023291:2114256-2114359 [Salmonella enterica subsp. enterica serovar Typhimurium]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37247 NZ_AP023291:c2114361-2114216 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References