Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2140883..2141028 Replicon chromosome
Accession NZ_AP023288
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-3835

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2140923..2141026 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2140883..2141028 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5610_RS10500 2137309..2138007 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5610_RS10505 2138031..2138687 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5610_RS10510 2138795..2139025 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5610_RS10515 2139163..2139537 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5610_RS10520 2139538..2140413 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5610_RS10525 2140430..2140783 + 354 WP_000722368.1 YebY family protein -
- 2140883..2141028 - 146 - - Antitoxin
- 2140923..2141026 + 104 - - Toxin
K5610_RS10530 2141157..2142080 - 924 Protein_2071 tyrosine-type recombinase/integrase -
K5610_RS24565 2142344..2142805 - 462 Protein_2072 DNA breaking-rejoining protein -
K5610_RS10540 2142794..2142985 + 192 Protein_2073 glycoside hydrolase family 19 protein -
K5610_RS10545 2143039..2143572 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5610_RS10550 2143829..2143996 - 168 WP_000789530.1 lytic enzyme -
K5610_RS10555 2144061..2144249 - 189 WP_001521334.1 hypothetical protein -
K5610_RS10560 2144304..2144564 + 261 Protein_2077 DUF1441 family protein -
K5610_RS10565 2144779..2145123 + 345 Protein_2078 macro domain-containing protein -
K5610_RS10570 2145133..2145603 + 471 Protein_2079 tail fiber assembly protein -
K5610_RS10575 2145700..2145900 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2135223..2173540 38317


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37175 NZ_AP023288:2140923-2141026 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37175 NZ_AP023288:c2141028-2140883 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References