285478

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 3355523..3355737 Replicon chromosome
Accession NZ_LN614756
Organism Clostridioides difficile strain 630Derm

Toxin (Protein)


Gene name CD0956.2 Uniprot ID Q183Z5
Locus tag CD630DERM_RS21035 Protein ID WP_003429855.1
Coordinates 3355576..3355737 (-) Length 54 a.a.

Antitoxin (RNA)


Gene name RCd10
Locus tag -
Coordinates 3355523..3355656 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CD630DERM_RS20325 3352739..3353308 - 570 WP_011861035.1 zinc-ribbon domain-containing protein -
CD630DERM_RS15600 3353352..3353912 - 561 WP_011861034.1 lipoprotein -
- 3355073..3355178 + 106 NuclAT_12 - -
- 3355073..3355178 + 106 NuclAT_14 - -
- 3355523..3355656 + 134 NuclAT_6 - Antitoxin
- 3355523..3355656 + 134 NuclAT_8 - Antitoxin
CD630DERM_RS21035 3355576..3355737 - 162 WP_003429855.1 hypothetical protein Toxin
CD630DERM_RS15610 3356078..3356518 - 441 WP_003429853.1 phage portal protein -
CD630DERM_RS15615 3356590..3357060 - 471 WP_003429851.1 phage tail tube protein -
CD630DERM_RS15620 3357077..3358387 - 1311 WP_011861032.1 phage tail sheath family protein -
CD630DERM_RS21040 3358389..3358565 - 177 WP_011861031.1 hypothetical protein -
CD630DERM_RS15630 3358558..3358995 - 438 WP_009901504.1 hypothetical protein -
CD630DERM_RS15635 3358988..3359413 - 426 WP_011861030.1 HK97 gp10 family phage protein -
CD630DERM_RS15640 3359413..3359760 - 348 WP_003429844.1 hypothetical protein -
CD630DERM_RS15645 3359754..3360155 - 402 WP_009888836.1 hypothetical protein -
CD630DERM_RS15650 3360165..3360398 - 234 WP_009896624.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3337900..3386080 48180


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 6120.42 Da        Isoelectric Point: 10.8938

>T285478 WP_003429855.1 NZ_LN614756:c3355737-3355576 [Clostridioides difficile]
MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFDFKIKFHKFK

Download         Length: 162 bp

Antitoxin


Download         Length: 134 bp

>AT285478 NZ_LN614756:3355523-3355656 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTTGCGGTAGAGTGAAGTTCATAATTAAATGAATCTATTTGAACTTATGGAACTTGATTTT
AAAATCAAATTCCCAGCCACTTTTACTCTTGCCACGAGTTGAGTGGCTTTTTAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069AVN2

Antitoxin

Download structure file

References