Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2073466..2073611 Replicon chromosome
Accession NZ_CP121262
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain 013

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2073506..2073609 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2073466..2073611 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8621_RS10090 2069892..2070590 - 699 WP_000944282.1 exodeoxyribonuclease X -
P8621_RS10095 2070614..2071270 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
P8621_RS10100 2071378..2071608 - 231 WP_000856224.1 DNA polymerase III subunit theta -
P8621_RS10105 2071746..2072120 + 375 WP_000168393.1 CopC domain-containing protein YobA -
P8621_RS10110 2072121..2072996 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
P8621_RS10115 2073013..2073366 + 354 WP_000722368.1 YebY family protein -
- 2073466..2073611 - 146 - - Antitoxin
- 2073506..2073609 + 104 - - Toxin
P8621_RS10120 2073740..2074663 - 924 Protein_1976 tyrosine-type recombinase/integrase -
P8621_RS10125 2074927..2075388 - 462 Protein_1977 DNA breaking-rejoining protein -
P8621_RS10130 2075377..2075568 + 192 Protein_1978 glycoside hydrolase family 19 protein -
P8621_RS10135 2075622..2076155 + 534 WP_001050882.1 DUF2514 domain-containing protein -
P8621_RS10140 2076412..2076579 - 168 WP_000789530.1 lytic enzyme -
P8621_RS10145 2076644..2076832 - 189 WP_001521334.1 hypothetical protein -
P8621_RS10150 2076887..2077147 + 261 Protein_1982 DUF1441 family protein -
P8621_RS10155 2077362..2077706 + 345 Protein_1983 macro domain-containing protein -
P8621_RS10160 2077716..2078186 + 471 Protein_1984 tail fiber assembly protein -
P8621_RS10165 2078283..2078483 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2067806..2106115 38309


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T276144 NZ_CP121262:2073506-2073609 [Salmonella enterica subsp. enterica serovar Typhimurium]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT276144 NZ_CP121262:c2073611-2073466 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References